Pediatric Drug Doses

184 Pediatric Drug Dosesotherwise 2 doses at 4 wk interval, if > 3years dose is0.5 ml. Revaccinate every year with strain adjusted vaccine.Brands: Vaxigrip; 7.5 mcg of A+7.5 mcg of B Virus antigen/0.25 ml.8. IPVIs an inactivated Salk strain vaccine. Given IM, 3 primarydoses at 6, 10, 14 wk or 8, 12, 16 wk; booster at 15 mths (atan interval of 6 mth from 3rd dose).Brands: Imovax, Polprotec; Contain type 1 > 40 DU + type2 > 08 DU + type 3 > 32 DU/0.5 ml.9. MeaslesLive attenuated Edmonston - Zagreb strain vaccine. GivenSC at 7-9 mth.of age as single dose.Brand: M-VAC; 1000 CCID50/0.5 ml.10. MMRLive attenuated vaccine. Given SC at 15-18 mth of age.Brands: Tresivac; Measles E-Z strain > 1000 CCID50 +M>R>A11u00m200700p/CsC3CLC>-IIZDD150s5000tpr+0aeirCMn0Cu.>5ImD5m0p50l0/.s0I0RnC.jI5.TCPmI4rDil3o,85ri05ni+xj>.;RM1u0eb0ae0slllCeasCRSIAcDh52w07+a/rR3zussbttrreaaliilnna11. MeningococcalAn inactivated capsular polysaccharide vaccine. Given IMin > 2 yr. of age during an epidemic, single dose followedby booster q 2 yr.Brands: Mancevax Inj; each 0.5 ml dose contain 50 mcg ofA, C, W and Y serotype. Meningococcal Inj; each 0.5 mldose contain 50 mcg of A and C serotype.

Vaccines 18512. OPVLive attenuated Sabin strain vaccine. Given PO 2 drops atbirth, 6, 10 and 14 wk. Booster at 18 mth. and 5yr.Brands: OPV 20 dose vial by Haffkine and GSK, containtype 1> 106, Type 2 > 105 Type 3 > 105.5 CCID50 per dose.13. Pneumococcal VaccineIs a polysaccharide vaccine available in 7 and 23 valentforms. Recommended in > 2yrs, 23 valent is given 0.5 mlIM or SC single dose followed by booster after 3-5 years.For 7 valent primary doses are given at 6, 10, 14 wk followedby booster at 12-15 mth.Brands: Pneumo - 23, Pneu-immune 23, 0.5 ml dose contain25 mcg of each serotype. Prevenar is a 7 valent and contain2 mcg of each serotype.14. RabiesIs an inactivated tissue culture vaccine. Available as humandiploid cell vaccine (HDCV), purified chick embryo vaccine(PCEV) and purified verocell rabies vaccine (PVRV). GivenIM, preexposure prophylaxis consist of 3 doses at 0, 7 and28 days and post-exposure schedule is 0, 3, 7, 14, 28 and 90days.Brands: Rabipur Inj; (PCEV) 0.5 ml/dose; Rabivax Inj;(HDCV) 0.5 ml/dose. Verorab Inj; (PVRV) 0.5 ml/dose.15. Rotavirus VaccineLive attenuated human rotavirus RIX 4414 strain vaccinecontaining not less than 106 CCID50. Given PO, 2 doses at4wk interval starting from 6 wk of age onwards.Brands: Rotarix; Single dose 1 ml.

186 Pediatric Drug Doses16. TdIs a low dose diptheria vaccine combined with tetanustoxoid, recommended in > 7y of age and should replace TTat 10 and 16 yr. Given 0.5 ml. IM.Brands: Td vac Inj; Contain D. toxiod < 5 Lf and T. toxoid >5 Lf/dose.17. TyphoidIs a purified Vi capsular polysaccharide vaccine. Given IMafter 2 years of age and booster every 3 years.Brands: Biovac, Typbar, Typhim Vi Inj; Contain 25 mcg ofSalmonella type 2 (Vi antigen).18. TTIs an alum precipitated toxoid vaccine, contain 5-25 Lf oftoxoid. Given 0.5 ml IM.Brand: Inj. BETT single dose ampoule.19. Varicella/Chicken Pox VaccineLive attenuated Oka strain vaccine. Given SC, single dosein 1-13 y and 2 doses in > 13 years with a gap of 4 wks.Brands: Varivax Inj; Contain > 2000 PFU/dose. Okavax Inj;Contain > 1000 PFU.

45 Vasodilators1. NitroglycerineUse: Shock, portal hypertension, CHF, hypertensiveemergencies.Dosage: In children by continuous infusion.Initial 0.25 - 0.5 mcg/kg/minute; titrate by 0.5 - 1 mcg/kg/min. q 3-5 min. to maximum of 5 mcg/kg/min.Brands: 5 mg/ml Inj ; NIG, Nitrocin, Nitroject.• For IV use dilute in D-5% or NS to 50 - 100 mcg/ml. Vasodilates veins more than arteries. May cause flushing, hypotension, reflex tachycardia, dizziness, headache.2. TolazolineUse: Treatment of persistent pulmonary hypertension.Dosage: Neonates; IV; 1-2 mg/kg loading dose followedby 1-2 mg/kg/hr continuous infusion.• May cause hypotension, tachycardia, increased respiratory and gastrointestinal secretions, GI bleed, flushing, pulmonary hemorrhage.3. Diazoxide, Hydralazine, Minoxidil, Nitroprusside,Phenoxybenzamine, Phentolamine, Prazocin - For detailsof these drugs see under antihypertensives.

46 VitaminsVITAMINS1. BiotinUse: Nutritional biotin deficiency, primary biotinidasedeficiency.Dosage: RDA: 10-200 mcg/day. Biotinidase deficiency: 5-10 mg once daily. Biotin deficiency: 5-20 mg once daily.Brands: 5 mg Tab; H-Vit, Oltin.2. Cyanocobalamin/Vitamin-B 12Use: Megaloblastic anemia, nutritional supplement,increased B12 requirement due to hemorrhage, liver orkidney disease.Dosage: RDA: 0.3 - 2 mcg/day.• Megaloblastic anemia: IM; 30-50 mcg/day to total dose of 1000-5000 mcg and then 100 mcg per month,• Deficiency: 100 mcg/day for 15 days then once or twice weekly for several month.BB1raannddsB: 61;0B0e0vmidcegx,BM12 aincr2abmarlianm. poule along with Vitamin

Vitamins 189• Severe hypokalemia may occur after conversion of megaloblastic anemia to normal erythropoiesis so serum potassium level should be monitored.3. Folic AcidUse: Megaloblastic and macrocytic anemia, tropical sprue.Dosage: RDA: Neonates to 6 mth; 30 mcg/day. 6 mth-3 y;50 mcg/day. 4-6 y; 75 mcg/day. 7-10 y; 100 mcg/day. >11 y; 150 mcg/day.Deficiency: 5 mg/dayBrands: 5 mg Tab; Fol-5, Folet, Folium, Folvite.• Large doses may mask the hematologic effect of B12 deficiency while allowing the neurologic complication due to deficiency to progress.4. Niacin/Vitamin - B 3Use: Treatment of pellagra, dietary supplement,hyperlipidemia,Dosage: RDA: 5-15 mg/day.Pellagra: 50-100 mg/dose 3 times/day.Hyperlipidemia: 10 mg/kg/day is maximum dose5. Pyridoxine/Vitamin - B6Use: Prevention and treatment of B6 deficiency, pyridoxinedependent seizures, treatment of drug induced deficiency,e.g. isoniazid, cycloserine, hydralazine.Dosage: RDA: 0.5-1.5 mg/day.• Pyridoxine dependent seizures: PO, IV, IM; 50-100 mg initial dose, maintenance dose: 50-100 mg/day, PO.• Dietary deficiency: 5-15 mg/day for 3-4 wk. then 2.5- 5 mg/day.

190 Pediatric Drug Doses• Drug induced neuritis: PO; For treatment 10-50 mg/day and for prophylaxis 1-2 mg/kg/day.Brands: 40 mg Tab; Benadon. 100 mg Tab; B-Long,Pyricontin. 100 mg pyridoxine + B1 + B6 Inj; Bevidox,Neurokem.• Sensory neuropathy may occur after chronic administration of large doses and large IV doses may precipitate seizures.6. Riboflavin/Vitamin-B 2Use: Prevention and treatment of riboflavin deficiency.Dosage: RDA: 0.5-1 mg/day.Deficiency: 2.5 - 10 mg/day in divided doses.Brands: 20 mg Tab; Lipabol.7. Thiamine/Vitamin - B1Use: Beri-beri, Wernicke's encephalopathy, peripheralneuritis.Dosage: RDA: 0.2-1 mg/day or 0.5 mg/1000 kcal diet.• Beriberi: PO, IM, IV; 10-30 mg/day for 2 wks. then 5-10 mg PO/day for 1 mth.• Encephalopathy: IM, IV; 100 mg/day until consuming a regular balanced diet.Brands: 75 mg Tab; Benalgis. 100 mg Tab; Beneuron forte,Berin. 100 mg/ml Inj; Berin.• Rapid IV administration may lead to cardiovascular collapse and death.8. Vitamin - AUse: Treatment and prevention of Vitamin-A deficiency,supplementation in children with measles.

Vitamins 191Dosage: RDA: 1000-3000 IU/day as per age.• Deficiency: PO; > 1 yr: 200, 000 IU for 2 days and then 1-4 wk. later. 6-12 mth, 1/2 of above dose and in < 6 mth 1/4 of the above dose and schedule.• Prophylaxis in patient at risk (malnutrition, severe infection, recurrent diarrhoea, pneumonia). In < 1 yr; 100,000 units and in > 1 yr; 200,000 units given PO q 4-6 mths.Brands: 50,000 units Tab and Cap; 50,000 units/ml Inj;Vitamin - A.• Hypervitaminosis -A may occur with massive doses or with large doses given over long period and manifest as nausea, vomiting, drowsiness, papilledema, symptoms of raised ICP.9. Vitamin-C/Ascorbic acidUse: Scurvy, urinary acidification.Dosage: RDA: 30 - 50 mg/day.• Scurvy: 100 - 300 mg/day.• Urinary acidification: 500 mg q 6 h.• To increase iron excretion during desferrioxamine therapy: 100 - 200 mg/day.Brands: 100 and 500 mg Tab; Celin, Cell-C. 100 mg/mldrops; Cecon, Celin. 100 mg/ml Inj; Redoxon, Tildoxon.10. Vitamin DUse: RicketsDosage: PO and IM; 1500 mcg or 600,000 IU. If no signs ofhealing on skiagram after 3-9 wks of therapy then repeatthe dose.Brands: 60,000 IU/Sachet; Calcirol granules (Alfacalcidol).3 lakh (7.5 mg) and 6 lakh (15 mg) IU/ml Inj; Arachitol(Vitamin-D3).

192 Pediatric Drug Doses• High dose of vitamin D3 given over long period may cause anorexia, vomiting, hypotonia, polydipsia, polyuria, hypercalcemia, hypercalciuria.11. Vitamin E/α TocopherolUse: Vitamin E deficiency treatment and prevention,nocturnal muscle cramps, prevention of retinopathy ofprematurity.Dosage: (1 mg = 1.5 units)• Prevention: Neonates; 5 units/day. Children; 10-20 units/day. Patients of Cystic fibrosis, Beta-thalassemia, Sickle cell anemia require higher daily maintenance doses.• Deficiency: Neonates; 25-50 units/day. Children; 1 unit/ kg/day.Brands: 200 and 400 mg Cap; Evion, Evit, Tocofer, 50 mg/ml drops; Evion.12. Vitamin-KUse: Nutritional supplement, hemorrhagic disease of thenewborn, prevention and treatment ofhypoprothrombinemia caused by Vitamin K deficiency oranticoagulant induced hypoprothrombinemia.Dosage:• HDN: 0.5 mg for preterm and 1mg for term neonate within 1hour of birth.• Children: IM, IV, SC; 1-2 mg/dose: PO; 2.5-5 mg/dose,Brands: 10 mg/ml Inj: kapilin (Vit K analog menaphthone)1 mg/0.5 ml and 10 mg/ml Inj; 10 mg Tab; kenadion.(phytomenadione).• Not effective in hypoprothrombinemia due to severe liver disease and hereditary hypoprothrombinemia.

47 Miscellaneous1. AlprazolamUse: Treatment of anxiety and panic disorder.Dosage: PO: 0.005 - 0.02 mg/kg/dose 3 times/day.Brands: 0.25 and 0.5 mg Tab; Alprax, Alzolam, Restyl.• Abrupt discontinuation may result in withdrawal symptoms. Safety not established in < 18 yrs.2. AtorvastatinUse: Hypercholesterolemia in patient not respondingadequately to diet and other measures.Dosage: PO: Children > 6 years: 10-80 mg/day once daily.Adjust dose as per lipid levels.Brands: 5, 10 and 20 mg Tab; Astin, Astorlip, Atorva.• May cause hepatitis, pancreatitis, gastritis, hyper- glycemia.3. AzathioprineUse: Adjunct with other agents in prevention of transplantrejection, as immunosuppressant in autoimmune diseaseslike SLE, nephrotic syndrome.Dosage: PO, IV:

194 Pediatric Drug Doses• Transplantation: Initial 2-5 mg/kg/dose once daily and maintenance dose is 1-3 mg/kg/dose once daily.• Other condition: 1 mg/kg/dose once daily for 6-8 wks.Brands: 50 mg Tab; Azimune, Azoprine, Immuran. 100 mg/vial; Immuran.• If used along with allopurinol reduce dose by 25-33%. Chronic immunosuppression increases risk of lymphoma and skin cancers. May cause irreversible bone marrow suppression.4. CharcoalUse: Emergency treatment in poisoning by certain drugsand chemicals, in overdoses of certain drugs to enhancetheir excretion (phenobarbitol, quinine, carbamazepine).Dosage: 1-2 g/kg or 5-10 times the weight of the ingestedpoison, may be given q 4-6 h.Brands: 400 mg activated charcoal + 80mg Simethicone: Tab.Distenil.• If given along with milk, ice cream may reduce its effectiveness.• May cause vomiting, constipation, black stools, intestinal obstruction.5. ChlorhexidineUse: As antibacterial, hand and dental rinse, surgical scrub.Dosage: Oral rinse: 5-15 ml twice daily. Cleanser: 5 ml perscrub or handwash.Brands: 0.2% mouth wash; Clohex, Hexitrin, Rexidin. 4%solution; 0.2% Lotion; Harifresh. 0.5% solution; Microgard.

Miscellaneous 195• Avoid eating for 2-3 h after oral rinse. May cause skin and tongue irritation, staining of oral surface.6. Cholestyramine ResinUse: Hypercholesterolemia, pruritis associated withelevated bile acids, diarrhoea associated with excess fecalbile acids.Dosage: PO: 240 mg/kg/day divided q 8 h.Brands: 4 gm sachet; Questran.• Avoid in biliary obstruction or atresia. For long term therapy, multivitamin, iron and folic acid is recommended in addition. May cause constipation, malabsorption of fat soluble vitamins, hyperchloremic acidosis.7. CisaprideUse: Nocturnal symptoms of GERD, gastroparesis,refractory constipation.Dosage: PO: 0.15-0.3 mg/kg/dose q 8 h. Maximum dose0.8mg/kg/day in neonates and 10 mg in infants andchildren.Brands: 10 mg tab; 1 mg/ml syrup; Cisapro, Ciza.• Administer 30 min before meals or feeding. May cause tachycardia, QT interval prolongation, arrhythmias.8. DextromethorphanUse: Symptomatic relief in non-productive cough.Dosage: 2-6y: 2.5-7.5 mg q 8 h. (Max:30 mg/day) 7-12y: 5-10 mg q 8 h. (Max: 60 mg/day) > 12y: 10-30 mg q 8 h. (Max: 120 mg/day)

196 Pediatric Drug DosesBrands: 10 mg tab; 30 mg/5 ml Syp; Lastuss. 10 mg/5 mlSyp; Suppressa.• May cause drowsiness, dizziness, nausea.9. DoxapramUse: Treatment of apnoea of prematurity not respondingto theophylline therapy.Dosage: Initial dose of 2.5 mg/kg followed by continuousinfusion of 1 mg/kg/h.(Max: 2.5 mg/kg/h).Brands: 20 mg/ml Inj; Caropram.• C/I in seizures, cerebral edema, respiratory problem. May cause HT, tachycardia, CNS stimulation.10. GlucagonUse: Hypoglycemia, beta-blocker overdosage.Dosage: IV, IM, SC:• Neonates, infants and children < 20kg: 0.02-0.03 mg/kg or 0.5 mg.• Children > 20 kg: 1 mg.Brands: 1mg/ml vial; Glucagon novo.11. GlycopyrrolateUse: Inhibition of salivation and excessive secretions of therespiratory tract, reversal of muscarinic effects of cholinergicagents.Dosage:• Control of secretions: PO: 40-100 mcg/kg/dose 3-4 times/day. IM, IV: 4-10 mcg/kg/dose q 3-4 h.• Pre-operative: IM: 4-5 mcg/kg 30-60 min; before procedure.

Miscellaneous 197• Reversal of muscarinic effects: IV: 0.2 mg for each 1 mg of neostigmine and 5 mg of pyridostigmine administered.Brands: 0.2 mg/ml Inj; Glyprolate, Pyrolate.• Infants with Down's syndrome, spastic paralysis or brain damage may be hypersensitive to its effects.12. GuaifenesinUse: Symptomatic treatment of cough (expectorant).Dosage: PO: <2 years: 12 mg/kg/day in divided doses.2- 5 years: 50-100 mg/kg/day. > 6y: 100-200 mg q 4 h.Brands: Axalin exp: Guai. 50 mg+Dextromethorphan 5 mg+ CPM 2.5 mg + Amm. chloride 60 mg/5 ml. Codicoff exp:Guai. 100 mg + Dextromethorphan 10 mg/5ml.• Administer with large quantity of fluid to ensure proper action.13. InsulinUse: Treatment of insulin dependent diabetes mellitus,hyperkalemia, diabetic ketoacidosis.Dosage: Only regular insulin can be given IV or IM.• Neonates: Regular insulin 0.01-0.1 unit/kg/h continuous infusion or 0.1-0.2 unit/kg q 6-12 h SC.• Children: 0.5- 1 unit/kg/day in divided doses SC, adjust dose as per blood glucose level.• Diabetic ketoacidosis: IV: Loading dose of 0.1 unit/kg followed by maintenance continuous infusion of 0.1 unit/kg/h, adjust as per blood glucose level.• Hyperkalemia: (Treat with IV calcium and sodium bicarbonate before giving insulin). Add 1 unit of regular insulin in 5 gm of dextrose solution, infuse at a rate of 0.5–1 gm/kg over 30 min followed by 0.1 unit/kg SC or IV.

198 Pediatric Drug DosesBrands: 40 unit/ml (neutral) Inj; Actrapid. 40 and 100 unit/ml (isophane) Inj; Human Insulatard. 30% soluble + 70%isophane insulin 40 unit/ml Inj; Huminsulin 30:70,Humstard 30:70. 50% soluble + 50% isophane insulin 40and 100 unit/ml Inj; Huminsulin 50:50.• May cause hypoglycemia leading to palpitation, pallor, fatigue, confusion, nausea, numbness of mouth, tremor and hypokalemia. Do not change brand once the blood glucose level is regulated.14. KetamineUse: Anesthesia for short procedure.Dosage: Give half an hour before procedure. IM; 3-7 mg/kg. IV; 0.5 -2 mg/kg. Continuous infusion; 5-20 mcg/kg/minute.Brands: 10 and 50 mg/ml Inj; ketalar, ketam, ketmin.• Contraindicated in raised ICT, HT, CHF, psychotic disorders. Used in combination with anticholinergic agents to decrease salivation.15. LoperamideUse: Short term use for symptomatic relief in non-infectiveacute and chronic diarrhea.Dosage: PO; 2-5 years: 1 mg TDS. 6-8 y: 2 mg BD. 8-12 y:2 mg TDS.Brands: 2mg tab; Andial, Imodium, Ridol. 1 mg/5 ml Syp;Andial.• May cause toxic megacolon and paralytic ileus.

Miscellaneous 19916. MupirocinUse: Impetigo, folliculitis, furunculosis, minor wounds,burns caused by S. aureus and S. pyogenes. Used intranasalto eradicate S. aureus carriers.Dosage: Apply cream or ointment 2-3 times/day for 5-14days.Brands: 2% Cream; Bactroban, Mupinova, 2% Oint;Mupirax, T-Bact.17. PancreatinUse: Pancreatic insufficiency.Dosage: Depends upon patient need. Varies from 5000-10,000 units. Swallow tablet whole. Take with a meal orsnack.Brands: Pancreatin 175 mg + Simethicone 50 mg + Charcoal50 mg; Tab. Medizyme. Pancreatin 192 mg + Bileconstituents 25 mg + Dimethicon 40 mg; Tab. B-zyme.• Inadequate dosing may lead to steatorrhea and overdoses to impaction.18. Prostaglandin E1Use: To maintain patency of ductus in ductus dependentcongenital heart diseases.Dosage: 0.05-0.1 mcg/kg/min. by continuous infusion.Maintenance dose is 0.01 mcg/kg/min.Brands: 500 mcg/ml Inj; Alpostin, Prostin VR.19. RacecadotrilUse: Symptomatic relief in diarrhea.

200 Pediatric Drug DosesDosage: PO: 1.5 mg/kg 3 times/day.Brands: 100 mg Cap; 10 and 30 mg sachet; Racedot, Raceloc,Zedott.20. Selenium SulfideUse: Seborrheic dermatitis, tinea versicolor, dandruff.Dosage: Topical in > 2 years:• Dandruff, Seborrhea: Apply twice weekly for 2 wks. then once weekly for 4 wks. Apply and leave for 5-10 min. and then rinse.• Tinea versicolor: Apply and leave for 30 min. and then rinse.Brands: 2.5% liquid; Selsun, Seldan.• Avoid contact with eyes and inflamed skin.21. Simethicone (Activated Dimethicone)Use: Relieves flatulance, functional gastric bloating, post-op gas pain.Dosage: PO; < 2y: 20 mg/dose q 4-6 h. 2-12 yrs. 40 mg/dose q. 6 h. > 12 y: 40-120 mg q 6 h.Brands: 40 mg/ml drops; Dimol, Siflat. 40 mg tab; Dimol.Simethicone 80 mg+Charcoal 400 mg tab; Gasnil.22. TacrolimusUse: As immunosuppressant in organ transplant, topicallyfor severe atopic dermatitis.Dosage: Children: PO; 0.2 mg/kg q 12h. Topical; Apply0.02% oint. locally twice.Brands: 1 and 5 mg tab; Crolium. 0.5, 1 and 5 mg Cap;Tacromus. 0.02% oint; Tacroderm, Tacrovate.

Miscellaneous 20123. Ursodeoxycholic AcidUse: Prevention and dissolution of small cholesterol gallstones, cholestatic conditions like primary biliary cirrhosis.Dosage: PO; 10-15 mg/kg/day in 1-2 divided doses.Brands: 150 and 300 mg Tab; Udihep, Udiliv, Urso. 75 mgTab; Actibile.• C/I: Calcified cholesterol stones, gall stones > 15 mm, hepatic impairment, biliary obstruction.

Index A non-narcotic 1 topical 9α tocopherol 192 urinary 10Abacavir 119 Anthelmintics 88Acetaminophen 4 Anti snake venom 129Acetazolamide 149 Antiarrhythmics 17Acetylcysteine 60 Antiasthmatics 11Acetylsalicylic acid 1 Antibiotics 21ACTH 70 Anticoagulants 55Acyclovir 133 Antidepressants 57Adenosine 17 Antidiphtheric serum (ADS)Adrenaline 11, 177Adrenocorticotropin (ACTH) 129 Antidotes/poisoning 60 170 Antiemetic therapy 75Albendazole 88 Antiemetics 66Albumin 172 Antifungals 81Alfacalcidol 168 Antigout agents 86Allopurinol 86 Antihemophilic factor 153Alprazolam 193 Antihistamines 93Amantadine 133 Antihypertensives 97Amikacin 21, 126 Antileprotics 105Amiloride 149 Antimalarials 106Aminocaproic acid 153 Antimyasthenics 111Aminoglycosides 21 Antiprotozoals 113Aminophylline 11 Antipsychotics 116Amiodarone 17 Antiretrovirals 119Amitriptyline 57 Antisecretories 131Amoxicillin 40 Antispasmodics 127Amphotericin B 81, 113 Antithyroid agents 180Ampicillin 41 Antitoxins 129Amprenavir 122 Antituberculars 124Amrinone 139 Antiulcers 131Analgesics 1 Antivirals 133 Anxiolytics 116 narcotic 6

210 Pediatric Drug DosesArteether 106 Cefaclor 29Artemether 106 Cefadroxil 28Artesunate 106 Cefazolin 28Ascorbic acid 191 Cefdinir 32Atenolol 97 Cefepime 33Atorvastatin 193 Cefixime 33Atropine 60 Cefoperazone 31Atropine sulphate 18 Cefotaxime 30Auranofin 1 Cefpirome 35Azathioprine 193 Cefpodoxime 34Azithromycin 37 Cefprozil 34Aztreonam 50 Ceftazidime 32 Ceftizoxime 34 B Ceftriaxone 30 Cefuroxime 29Baclofen 175 Cephalexin 35BCG 182 Cephalosporins 28Beclomethasone 11 Cetrizine 93Benzocaine 9 Charcoal 61, 194Benztropin 60 Chelating agents 141Benzyl benzoate 174 Chicken pox vaccine 186Betamethasone 145 Chloramphenicol 50Biotin 188 Chlordiazepoxide 116Bisacodyl 164 Chlorhexidine 194Budesonide 12 Chloroquine 107, 113Bumetanide 150 Chlorpheniramine maleate 93 Chlorpromazine 61, 116 C Chlorthalidone 150 Chlorzoxazone 175Calcium gluconate 155 Cholestyramine resin 195Captopril 97 Cimetidine 159Carbamazepine 70 Ciprofloxacin 47Carbapenem 26 Cisapride 195Carbenicillin 42 Clarithromycin 37, 126Carbimazole 180 Clemastine fumerate 94Cardiac shocks and failures Clindamycin 36 Clobazam 71 139 Clofazimine 105Carnitine 168Cedofovir 134

Index 211Clonazepam 71 Diltiazem 99Clonidine 98 Dimenhydrinate 66Clotrimazole 82 Dimercaprol 142Cloxacillin 42 Dimercaptosuccinic acid 62Codeine 6 Diphenhydramine 62, 94Colchicine 86 Diphtheria antitoxin 129Colistin sulfate 51 Disopyramide 19Colony stimulating factors Diuretics 149 Dobutamine 177 143 Docusate 164Corticosteroids 145 Domperidone 66Cortisone 146 Dopamine 178Crotamiton 174 Doxapram 196Cyanide kit 61 Doxepin 57Cyanocobalamin 188 Doxycycline 49Cycloserine 124 D-penicillamine 62, 142Cyproheptadine hydrochloride DPT 182 Drotaverine 127 94 E D Edetate calcium disodium 62Dapsone 105 Edrophonium 111Deferiprone 61, 141 Efavirenz 121Desferrioxamine 61, 141 Electrolyte supplements 155Desloratidine 94 Enalapril 99Desmopressin 170 Enoxaparin 55Dexamethasone 146 Epinephrine 11, 177Dextran 173 Ephedrine 178Dextromethorphan 195 Erythromycin 38Dextrose 156 Erythropoietin 143Diazepam 72 Ethacrynic acid 150Diazoxide 98, 187 Ethambutol 124Diclofenac sodium 2 Ethamsylate 153Dicyclomine 127 Ethanol 63Didanosine 119 Ethionamide 124Diethyl carbamazine (DEC) 89 Ethosuximide 73Digoxin 139Digoxin immune fab 61

212 Pediatric Drug Doses F HFamciclovir 134 H antagonists 159Famotidine 159 2Fat emulsion 168Fentanyl 6 Haloperidol 116Fexofenadine 95 Hamycin 83Fluconazole 82 Heparin 55Fludrocortisone 147 Hepatitis A 183Fluid replacements 155 Hepatitis B 183Flumazenil 63 Human anti-D (RHo-D)Fluoride 166Fluoxetine 58 immunoglobulinFluticasone 12 160Folic acid 189 Human hepatitis-BFormoterol 13 immunoglobulinFoscarnate 134 161Fosphenytoin 73 Human normalFurazolidone 51 immunoglobulinFurosemide 150 (IVIG) 161 Human rabies G immunoglobulin 162Gabapentin 73 Human tetanusGamma benzene immunoglobulin 162 hexachloride Hydralazine 99, 187 (GBHC) 174 Hydrochlorothiazide 151Gancyclovir 135 Hydrocortisone 147Gas gangrene antitoxin 130 Hydroxyzine 95Gatifloxacin 47 Hyoscine butylbromide 128Gentamicin sulfate 22 Hyperbaric oxygen 63Gentian violet 83Glucagon 63, 196 IGlycopyrrolate 196Granisetron 67 Ibuprofen 2Griseofulvin 83 Idoxuridine 135Guaifenesin 197 Imipenem 26 Imipramine 58 Immunoglobulins 160

Indinavir 122 Index 213Indomethacin 3Influenza virus vaccine 183 Lopnavir 122Insulin 197 Loratidine 95Interferon alfa 135 Lorazepam 74Ipratropium 13IPV 184 MIron 166Isoniazid 125 Macrolides 37Itraconazole 83 Magnesium sulfate 155Ivermectin 90 Mannitol 151 Measles 184 K Mebendazole 90 Meclizine 67Kanamycin 126 Medium chain triglyceridesKanamycin sulfate 23Ketamine 198 169Ketoconazole 84 Mefenamic acid 3Ketorolac 3 Mefloquine 108 Meningococcal 184 L Meperidine 8 Meropenem 26Labetalol 100 Methocarbamol 175Lactulose 164 Methyldopa 100Lamivudine 120, 136 Methylene blue 63Lamotrigine 74 Methylprednisolone 147Lansoprazole 131 Metoclopramide 67Laxatives 164 Metoprolol 100Levamisole 90 Metronidazole 113Lidocaine 9, 19 Mexiletine 19Lincomycin 36 Miconazole 84Lincosamides 36 Midazolam 75Linezolid 52 Milrinone 140Liothyronine 180 Minerals 166Liquid paraffin 165 Minocycline 49Lithium 58 Minoxidil 101, 187Loperamide 198 MMR 184 Montelukast 13 Morphine sulphate 7 Mupirocin 199

214 Pediatric Drug Doses N OPV 185 Ornidazole 114Nalidixic acid 48 Oseltamivir 136Naloxone 64 Oxcarbazepine 76Naproxen 4Nelfinavir 122 PNeomycin 23Neostigmine 111 Pancreatin 199Netilmicin sulfate 24 Pantoprazole 131Nevirapine 121 Para-amino salicylic acid 125Niacin 189 Paracetamol 4Niclosamide 91 Paraldehyde 76Nifedipine 101 Penicillin G aqueous 42Nimesulide 4 Penicillin G benzathine 43Nitazoxanide 114 Penicillin G procaine 44Nitrazepam 76 Penicillin V potassium 44Nitrofurantoin 52 Penicillins 40Nitroglycerine 187 Pentamidine 114Nitroprusside 102, 187 Pentazocine 7Non-nucleoside reverse Permethrin 174 Pethidine 8 transcriptase Pheniramine 96 inhibitors 121 Phenobarbital 76Nor-epinephrine 178 Phenoxybenzamine 102, 187Norfloxacin 48 Phentolamine 102, 187Nortriptyline 59 Phenylephrine 179Nucleoside 119 Phenytoin 19, 77Nucleotide reverse Physostigmine 64 transcriptase Phytomenadione 65 inhibitors 119 Pilocarpine 64Nutritional supplements 168 Piperacillin 45Nystatin 84 Piperazine 91 Piroxicam 5 O Pituitary hormones 170 Plasma volume expandersOctreotide 64Ofloxacin 48 172Omeprazole 131 Pneumococcal vaccine 185Ondansetron 68 Polymyxin B sulfate 52

Potassium chloride 156 Index 215Pralidoxime 64Praziquantel 91 Ribavirin 137Prazosin 103, 187 Riboflavin 190Prednisolone 148 Rifampicin 105, 126Primaquine 108 Rimantadine 137Primidone 78 Ritonavir 123Probenecid 86 Rotavirus vaccine 185Procainamide 19 Roxithromycin 39Prochlorperazine 68Promethazine 69, 96 SPropantheline bromide 128Propranolol 20, 103 Salbutamol 14Propylthiouracil 180 Salmeterol 14Prostaglandin 199 Scabicidal agents 174Protamine 65, 154 Secnidazole 115Protease inhibitors 122 Sedatives 116Proton pump inhibitor 131 Selenium sulfide 200Pseudoephedrine 96, 179 Sertraline 59Pyrantal pamoate 92 Simethicone 200Pyrazinamide 125 Skeletal muscle relaxants 175Pyridostigmine 112 Sodium bicarbonate 157Pyridoxine 65, 79, 189 Sodium chloride 157Pyrimethamine 109 Sodium cromoglycate 14 Sodium stibogluconate 115 Q Somatropin 171 Sotalol 20Quinidine sulfate 20 Spironolactone 152Quinine 109 Stavudine 120Quinolones 47, 126 Stool softeners 164 Streptomycin 24, 126 R Sucralfate 132 Sulphadoxine 109Rabies 185 Sympathomimetics 177Racecadotril 199Ranitidine 159 TRespiratory syncytial virus Tacrolimus 200 immunoglobulin Teicoplanin 53 162 Terbinafine 85 Terbutaline 15

216 Pediatric Drug DosesTetanus antitoxin 130 Valproate sodium 80Tetracyclines 49 Vancomycin 54Theophylline 15 Varicella 186Thiamine 190 Varicella zosterThiopental 79Thioridazine 117 immunoglobulinThyroid agents 180 163Thyroxine 181 Vasodilators 187Ticarcillin 45 Vasopressin 140Tinidazole 115 Verapamil 104Tobramycin 24 Vigabatrin 80Tolazoline 187 Vitamins 188Tolmetin 5 vitamin A 190Tolnaftate 85 vitamin B1 190Topiramate 79 vitamin B2 190Tranexamic acid 154 vitamin B3 189Triamcinolone 148 vitamin B6 189Triamterene 152 vitamin B12 188Triclofos 117 vitamin C 191Trifluoperazine 117 vitamin D 191Trifluridine 137 vitamin E 192Typhoid 186 vitamin K 192 Voriconazole 85 U WUrsodeoxycholic acid 201 Warfarin 56 V ZVaccines 182Valacyclovir 138 Zafirlukast 16 Zidovudine 120 Zinc 167