2015 Biotech Times magazine

VOLUME 4 • ISSUE 1 UC Davis October 2015 BiotechTimes Marianne Hunter - Editor FEATURES: • New NIH/Biotech Fellows • 2014-15 Graduates Placed • Internships Placed • New NIH Website Launched Annual Biotechnology Program Magazine

CONTENT WELCOME! 3 Message from the Director 7 NIH-NIGMS Training Program in Biomolecular Technology Biotechnology Trainee Fellowship Recipients FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG 8 DEB Program 9 24th Annual Biotech Training Retreat 9 ADP Program 10 Congratulations to Recent DEB Graduates 11 Biotechnology Internships (MCB 282) 12 Biotech Program’s Social Media 13 Biotech Event at Picnic Day 14 BioTech SYSTEM News 16 Pizza Chalk Talks 17 MCB/ECH Friday Seminars Schedule 18 MIC 292 From Discovery To Product The UC Davis Biotechnology Program is very busy all year long! Welcome to our annual magazine where we get to 19 Mark Your Calendars show of some of the many programs and activities that we 20 Biotech Program Contact are involved with throughout the academic year. Information Have something interesting to share? Contact us so we can post it on our various social media outlets. DEB STATISTIC On the cover: 2014-15 NIH/Biotech Fellows at the 2015 Annual Biotechnology Training Retreat in Napa. There have been 205 DEB students since L-R Front: Anna Marie Tuaazon, Nicole 2002 that have graduated with a PhD and Nozzi, Sam Westreich, Allison Hoch, and Rosanna Kwok also received their designated emphasis L-R Back: Doug Gettel, Christopher in biotechnology on their diploma. That Siltanen, Keith Dunaway, Johnathon Anderson, and Casey Boosalis also means 205 paid internships have been successfuly completed! 2 2

MESSAGE FROM THE DIRECTOR Welcome to the 2015 edition of the Biotech Times. training program that addresses the needs of This past year has passed by very quickly due to the 21st Century. The DEB serves as a powerful all of our many projects. We even hired another recruitment tool for the campus. Each fall, I administrative assistant to have the honor to talk about the DEB and the ease the workload. Please NIH T32 Biotech Training Grant at the BMCDB welcome Jacqueline Phillips Colloquium as well as address the irst year PhD to our Biotech family. students in the NIH IMSD Program (focused on She has been a wonderful underserved populations). We are very proud of addition to our team. In the fact that over 20% of our DEB students are addition, we hired a part from underrepresented minority populations. I feel time budget analyst to that the additional mentoring and the enhanced assist us with high level experiences help to retain these students so that analysis and forecasting. they earn their PhDs. Ms. Kelly Meade’s irst day was September 1, 2015. She has a degree in In the 2014-15 academic year, we placed 23 accounting from Sacramento State. We plan to students in internships (industry and campus). keep her very busy! Most were place in California, but some were in pharmaceutical companies on the east coast and Our stellar Designated Emphasis in Biotechnology a few were international. The College of Biological (DEB) program continues to grow in the number Sciences and the Biotechnology Program have a of students, faculty and graduate programs. The new partnership with Allergan, Inc. in Irvine, CA. FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG DEB currently has over 210 PhD students from 30 A formal MOU was created to commit to taking diferent disciplines and 18 students graduated up to two DEB students per year. We are sending in the 2014-15 academic year. This gives us 201 our irst student this fall. Without our industry and graduates since the beginning of the program campus partners, the DEB could not continue to be in 1997. We continue to be the largest DE on such a stellar program. Please see the newsletter campus ofering a unique pre-doctoral graduate for more information. Equity issues are still a concern and the Biotechnology Program wants to be a leader in this efort. In 2013, our DEB students, Jeni Lee and Nicole Chafee led the WiL (Women in Leadership) series. In 2014-2015, Anna Marie Tuazon and Ailsa Dagliesh took over the leadership and created ESTEME (Equity in STEM and Entrepreneurship) so that it addresses issues of women and men. In 2015-2016, we have Doug Gettel and Samantha Feng leading the way. Please see the website for more information: http://biotech.ucdavis.edu/ ESTEME/index.html 3

DIRECTOR’S MESSAGE (Cont) People are noticing the Last January, I was a DEB and the support of keynote for UC Davis Leadership and Equity. WRRC’s Women of On Sept. 9, 2015, I was Color Symposium. The asked to be the keynote title of my talk was for the Bioscience “An Entrepreneurial FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Career Track at Oregon Spirit- a Key to Success” Bio 2015 in Portland, (based on the DEB Oregon. The focus of model). Last March, I my presentation was was honored to receive on our DEB program. one of the Chancellor’s The title of the talk was Achievement Award “Maximizing Your Full for Diversity and Potential as a Scientist Community. It is nice courses. Marianne Biotechnology Training in the 21st Century”. I to be recognized Hunter is overseeing this Grant in the newsletter was also part of a panel for our hard work in huge efort. We owe her for more information on discussion on Women transforming graduate a big thank you for her each fellow. We are so in Leadership in STEM. education. hard work. I guess the proud of our 2015-2016 On Feb 23, 2015, I was DEB graduate program Fellows, they represent invited to present to Due to restructuring is no long a pilot the cross disciplinary post-docs about careers with the MCB (Molecular program; it is becoming nature of our program so and empowerment at & Cellular Biology) institutionalized. We well. They can be found the Buck Institute in department, our courses hope some funding on our website at http:// Novato. Again, I used will have our own course comes with this change! www.niht32.ucdavis. the DEB as a successful codes – DEB 294, DEB edu/Current_Fellows. model. See blog http:// 263 and DEB 282 and As stated last year, sage.buckinstitute.org/ the Biotechnology we received another The Advanced Degree maximizing-your-full- Program will coordinate 5 year competitive Program (ADP) for potential-as-a-scientist/. the staing for the renewal of the NIH corporate employees T32 Graduate Training is still operating, but Program in Biomolecular the great recession Technology in 2012. We slowed our growth. As even received an extra the economy improves, slot from NIH, so we we hope to add 1-3 can fund 10 outstanding new participants in the scholars each year. upcoming year. As more We are in the planning companies move into stages for submitting the region, this program another renewal in the will be a great vehicle spring of 2016. We will for retention of excellent need a lot of support employees who wish from our campus to earn a doctoral leaders and our industry degree. The magazine partners so that we can has more details on the continue this stellar participants. One of our Biotechnology Training most recent graduates Program. Please see of the program was the section on the Shaunese Lambel, who 4

DIRECTOR’S MESSAGE (Cont) DIRECTOR’S MESSAGE (Cont) received her PhD in Genetics. free to high school She works at Harris Moran Seed and community Co and her corporate mentor college instructors was Eileen Kabelka and UC Davis would not exist! mentor was Prof. Roger Chetelat. We depend on the Brooks Hayes from Expression generosity of our Systems received his PhD in life science industry Biochemistry, Molecular, Cellular partners to serve & Developmental Biology and our community of his corporate mentor was Thera researchers and Mulvania and UC Davis mentor, teachers. Professor Bruce Hammock. Community We ofered two short courses Outreach activities over the summer, Flow are an important Cytometry and Proteomics. part of our on Pharmaceutical R&D and We are fortunate to have eforts to pay it forward. The Manufacturing in California at two wonderful instructors for BioTech SYSTEM, Teen Biotech the State Capitol in regards to these intensive classes who the efects of NIH sequestration received stellar reviews from on university biomedical the participants at the end of research and training. I urged the instruction. Thank you Bridget committee to increase funding McLaughlin, director of the to UC so we could continue to be FACS facilities on the Davis and a leader in biotechnology-related FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Sacramento campuses and to research. Last fall, I was selected Dr. Brett Phinney, director of the as an Inspirational Mentor for Proteomics Core Facility in the the One UCDAVIS Banner Genome Center! Campaign. I love mentoring A big thank you also goes students (high school to PhD level). Please check out the to Dr. David Hedin, the CEO banner at http://ucdavis.edu/ and Founder of Expression one/stories/mentors/kjelstrom- Systems who is a wonderful sahota.html . industry partner. Without his Challenge, CIRM Creativity generous support, our Train Grant, Picnic Day Biotech Since 2012, Denneal and I the Trainers course ofered for Event, advisory roles for High have served on the Education School Biotech Academies Committee for the new and the Power House Science PowerHouse Science Center in Center, Science Communication Sacramento. This summer, I was Fellows, Dinner with a Scientist, asked to chair the Education presentations and campus tours Committee as we get closer keep Denneal, the DEB students to breaking ground for the and me very busy. On February new science center on the 12, 2014, I was asked to testify Sacramento River. I continue on behalf of UC Davis to the to serve on the Executive Assembly Select Committee Board of Directors so that UC on Biotechnology Hearing Davis has a strong presence 5

DIRECTOR’S MESSAGE (Cont) need for strategic career planning, entrepreneurship and advanced level network development. I continue to join my Leadership California alumnae in meetings with delegations of women leaders and entrepreneurs from all over the world. These women are part of the U.S. Department of State’s FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG “100 Women Initiative: Empowering Women and Girls through International Exchanges”. It is an honor to share our Best Practices in education, equity, technology and business development as well as leadership. Denneal has been very active with the UC Davis ADVANCE Program to advance on this important project. This promises to be opportunities for women faculty. Last year, two a wonderful regional hub for STEM research, of our DEB students, Jeni Lee and Nicole Chafee education and career explorations. In 2012, the did a fantastic job in organizing the Women in Powerhouse Science Center was selected as one Leadership (WiL) STEM series. Last spring, we of 10 NSF funded PopNet (Portal to the Public) led a panel discussion on Women in Leadership centers in the U.S. for informal science training. I for the U.S Embassy Stafer in cooperation with recommended 10 PhD students to be trained as the Northern California World Trade Center and the inaugural Science Communication Fellows. Leadership California. Denneal, Professor Karen Since then, another 25 DEB students have been McDonald, Jeni, Nicole and I spoke candidly about trained as Science Communication Fellows. equity in STEM disciplines. By the way, Denneal This is a wonderful program for learning how to is completing her year of California Issues and efectively communicate science to the public. Trends Program this year, so she will be an alumna Our communication fellows demonstrated their of Leadership California in 2016. The journey in teaching tools at the Angels for Hearts “When I leadership is an ongoing efort. Grow Up” event again this summer and were a big hit. As a result of our successful Teen Biotech Enjoy our magazine. Challenge competition, Dr. Jan Nolta and Dr. Gerhard Bauer from the Institute of Regenerative Dr. Judy Kjelstrom Cures in the School of Medicine and the Biotechnology Program wrote a Creativity grant to the California Institute for Regenerative Medicine (CIRM). We are in the last year of a three year grant to provide 10 TBC winners with a paid summer research experience in stem cell biology. We are submitting a new CIRM Creativity grant proposal this fall. We hope to be renewed by CIRM because these high school students love this opportunity to do research and present a scientiic poster at the annual conference. Denneal and I continue to be involved in leadership and mentorship issues, especially for women in STEM. There is a 6

NIH-NIGMS TRAINING PROGRAM 2015-16 NIH/ Developmental Biology (Luis Carvajal-Carmona, BIOTECH Preceptor). Population Isolates From Columbia TRAINEE Enable Identiication of Novel Breast Cancer RECIPIENTS Risk Genes. Sana Vaziri, Computer Sciences (Sharon Aviran, Congratulations Preceptor). Data Driven Integration of Multiple to the outstanding Probe Measurements. students who were selected as Biotech the 2015-2016 Joshua Cohen, Food Science (Daniela Barile, NIH and Biotech Preceptor). Cloning Biidobacterial Enzymes to Fellows. There Release Bioactive Glycans. were 28 fellowship Daniel Lewis, Integrative Genetics & Genomics applicants this (Cheemang Tan, Preceptor). Competitive year and all were Regulations Modulate Topology of Gene exceptional Networks. candidates! Debika Mitra, Biomedical Engineering (Kent Leach, Preceptor). Interrogating Collagen NIH Crosslinks in Engineered Matrices as a Model Karan Agrawal, Pharmacology & Toxicology for Bone Repair in Diabetic Patients. (John Newman, Preceptor). Using Sam Westreich, Integrative Genetics & metabolomics to develop non-invasive Genomics (Ian Korf, Preceptor). Novel Methods FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG diagnostic methods for inlammatory skin in Metratranscriptomics: Examining the Gut diseases. Microbiome of Idiopathic Chronic Diarrhea. Jasmine Corbin, Chemical Engineering (Karen McDonald, Preceptor), Process Development We are grateful to Monsanto for their industry for the Production of a Heterologous fellowship as well as to the campus for their NIH Glycoprotein in Transgenic Rice Cell Culture. fellowship matching support! Rosanna Kwok, Entomology (Joanna Chiu, Preceptor). Temporal Dynamics of Epigenetic Landscape Enable Fine- Tuning of Circadian Transcription in Drosophila Nicole Nozzi, Chemistry (Shota Atsumi, Preceptor). Developing Production of a Plant Alkaloid in a Microbial Host. Anna Marie Tuazon, Biochemistry, Molecular, Cellular and 7

DESIGNATED EMPHASIS IN BIOTECHNOLOGY PROGRAM (DEB) • To allow cross- disciplinary training and trainee experience in a biotechnology company or cross college FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG laboratory. This program supplements a student’s Ph.D. curriculum and those completing the DEB Program will obtain an oicial designation on their diploma and transcript indicating THE DESIGNATED groups. The UC Davis EMPHASIS IN Biotechnology Program BIOTECHNOLOGY is the administrative (DEB) home for this program. graduate program is an inter-graduate group The DEB provides a program that allows nurturing, interactive Ph.D. students to environment to promote receive and be credited integration of multiple for training in the area of disciplinary approaches biotechnology. to conduct research and to promote learning in There are approximately biotechnology. 230 students from 30 diferent graduate The DEB helps: • To provide well- coordinated, cross- a qualiication in biotechnology. disciplinary training of graduate students Course requirements in critical areas of are covered on the DEB biomolecular technology research. website.. • To promote interdisciplinary research environments that integrate basic biological science, engineering and computational disciplines. 8

24TH BIOTECH RETREAT ADP PROGRAM ON MARCH 14TH, THE BIOTECHNOLOGY Program held their 24th Annual Training Retreat for THE ADVANCED DEGREE PROGRAM (ADP) fellowship recipients and their mentors, industy ailiates for Corporate Employees is a program that and our DEB students and faculty members. The retreat allows the working professional to complete a is held each Winter or Spring Quarter at the Christian doctorate in a number of graduate programs Brothers Retreat and Conference Center in the Napa within the Biological Sciences and Engineering Valley. Mark your calendars for the 2016 Retreat which programs. The ADP is coordinated by the will be held on March 5th! Biotechnology Program in conjunction with Graduate Studies, the College of Biological During the retreat, the fellows and invited industry Sciences, and the College of Engineering. ailiates gave oral presentations on their research. In addition to these oral presentations, poster sessions The ADP is a very successful academic-industry (open to all attendees) are held to stimulate one-to-one partnership and one of the highlights of the interactions, provide networking opportunities, and year is our annual luncheon in which the faculty possible collaborations. and administrators interact with ADP students Every retreat, a bioethics question is presented, followed and the corporate mentors. It is also a time to by answers and discussions. Dr. Denneal Jamison- introduce the program to prospective company McClung, the Associate Director of the Biotechnology employees. Program presented her ethics discussion on, “ZMapp Can Zap Ebola!... Or, Can It? Mobilizing a Global Congratulations go to: Response to a Public Health Crisis”, in which a very lively Brooks Hayes (BMCDB Graduate Group) from discussion followed with excellent answers! Expression Systems who received his PhD in 2014. Brook’s industry mentor was Dr. Thera Mulvania and his UCD mentor was Professor Bruce Hammock. FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Shaunese Lambel (Genetics Graduate Group) from HM Clause who received her PhD in 2014. Her industry mentor was Dr. Eileen Kabelka and her UC Davis mentor was Professor Roger Chetelat. Thank you to Dr. Timothy Conner (Monsanto), Dr. Christopher Muriel (OncoMed Pharmaceuticals), Dr. Alice Yam (Sutro Biopharma, Inc.); Dr. Jeannie Giacchino (Bavarian Nordic, Inc.), and *Dr. Gian Oddone (Agrinos, Inc.) for joining us to share information about the latest from their companies and to meet our fellows! *Gian Oddone was a DEB graduate student as well as an NIH Fellow! It’s great to have former students keep in touch! 9 9

CONGRATS TO RECENT DEB GRADUATES! “26 DEB grads, Computer Engineering, now an electrical engineering postdoc 2014-15 academic Fellow at Lawrence Berkeley year” National Lab. Siobhan Halloran (PI: Bill THROUGHOUT THE 2014-2015 Ristenpart) PhD Chemical FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG academic year, there were 26 Engineering, a postdoctoral students in the DEB Program fellow at Icahn School of who received their PhDs along Medicine at Mount Sinai School with a Designated Emphasis in of Medicine. Biotechnology. These exemplary Allison Hoch (PI: Kent Leach) students took the full DEB PhD Biomedical Engineering, now coursework, including the 3 – 6 a Clinical Science Consultant at months internship (MCB 282). Boehringer. The Biotechnology Program is Vicki Hwang (PI: Robert Weiss) very proud of the hard work they PhD Integrative Genetics Athanasiou) PhD Biomedical put in to achieve their goals and & Genomics, now Postdoc at Engineering, co-founder of ViVita would like to recognize them in this UC Davis’ Internal Medicine, Technologies. magazine. Nephrology, Robert Weiss Lab. Karen LeGrand (PI: Glenn Young) Rachel Kerwin (PI: Dan PhD Microbiology, now US Borlaug Lisa Anderson: (PI: Annaliese Kliebenstein) PhD Plant Biology, Global Food Security as a Graduate Franz) PhD Chemistry, now a now postdoc in the Sweigart Lab, Research Fellow at US Agency postdoc in the Prather chemistry Dept of Genetics at the University for International Development lab at Massachusetts Institute of of Georgia in Athens, GA (USAID). Technology Jennifer Lee (PI: Kyriacos Alan Lombard (PI: Maria Mudryj) Jesse Bakke (PI: Fawaz Haj) PhD PhD Biochemistry, Molecular, Nutritional Biology, now a postdoc at Saint Jude Children’s Research Patricia Castillo (PI: Charles Bevins) FAST DEB FACTS Hospital. PhD Immunology, postdoc at UC Davis department of Medical Average time for a DEB student to Microbiology & Immunology. graduage with a PhD and DEB on Arnold Chen (PI: Tingrui Pan) PhD their diploma is 5 years, 1 quarter. Biomedical Engineering, now a R&D Scientist Agilent Technologies. The percentage of DEB male and Elieke Demmer (PI: Marta van female students is practically the Loan) PhD Nutritional Biology, now same. There are only 14 more RD Manager Nutrition Research at female students. Dairy Management, Inc. Anna Erickson (PI: Anna Fisher) More DEB students come from the PhD Biochemistry, Molecular, Biochemistry, Molecular, Cellular Cellular & Developmental Biology, & Developmental graduate group now Postdoctoral Fellow at than any other. Stanford University. Erin Fong (PI: Rajeevan There have been over 605 DEB Amirtharajah) PhD Electrical & students enrolled in the program since 2000. 10 10

RECENT GRADS (Cont) BIOTECH INTERNSHIPS Cellular & Developmental Biology, now Post-doc - One of the requirements of the Designated Allen Gao’s lab at UC Davis. Emphasis in Biotechnology graduate program Kevin Martin (PI: Jared Shaw) PhD Chemistry, now is interning for at least three months at postdoc fellow at California Institute for Biomedical a cooperating biotechnology company, Research & Scientiic Collaborator at Scripps government agency or a cross-college site. Research Institute. Many DEB students have completed their Jared Moore (PI: Jared Shaw) PhD Chemistry, now a internships over the past year and several have NIH Postdoctoral Fellow at Caltech. started this fall. We are sending our students to Meghan Murphy (PI: Kyriacos Athanasiou) PhD diverse locations, even international sites. Biomedical Engineering, now a biomedical engineer at The Shop Innovation Lab, VSP Global, We wish to thank all of our industry partners Sacramento. who ofered internships for our DEB students. John Oliver (PI: Shota Atsumi) PhD Chemistry, now See where our students interned during the Post doc at Harvard Medical School and the Wyss 2014 -2015 academic year: Institute with Pamela Silver. Nadia Ono (PI: Li Tian) PhD Biochemistry, Agilent Technologies, Santa Clara: Arnold Chen Molecular, Cellular & Developmental Biology. American River College, Los Rios Teaching Dipali Patel (PI: Alexander Revzin), PhD Biomedical College: Geofrey Benn Engineering. Amplimmune, Gaithersburg, MD: Alan Jonathan Pham (PI: Scott Dawson), PhD Lombard Microbiology, now a postdoc at Novozymes. Amyris Biotechnologies, Emeryville: Lisa Gabriel Rodriguez (PI: Shota Atsumi), PhD Anderson Chemistry, now postdoc at Clemson university, Aquilo Capital Management, SF: Jennifer Lee South Carolina. (also ViVita Technologies, Davis, CA) FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Amy Schroeder (PI: Marty Privalsky), PhD Bayer CropScience, Berkeley, CA: Ben Golomb Biochemistry, Molecular, Cellular & Developmental Bayer HeathCare, Berkeley, CA: Wade Zeno Biology, now at Genentech; Regulatory Afairs Celgene: Brian Avanzino, Intern supporting HER2 group. Chelsea Snyder (PI: Marty Privalsky), PhD Microbiology, now a Research Scientist at Gilead Sciences. Katherine Walker (PI: Simon Cherry), PhD Biomedical Engineering. Abigail Yu (PI: Ian Korf & David Segal), PhD Integrative Genetics & Genomics, now Associate Research Scientist at Sutro Biopharma, SF. Nancy Zeng (PI: William Ristenpart), PhD Chemical Engineering, now Process Genentech Facility in South San Francisco Engineer at Intel Corporation, Sacramento, CA. 11 11

INTERNSHIPS SOCIAL MEDIA FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG The Biotechnology Program uses various forms of social media to Celgene (cont): Kateryna Feoktistova promote its program, students, Emory University: Kevin Martin faculty, and many activities. Genentech, SF: Chelsea Snyder, Shailise Ross, Allison Hoch, Brandon See below for some of the tools Brown, Tin Ngo, Siobhan Halloran, we use to get our messages Christian Siltanen, Marjannie Eloi- across. Akintunde Glaxosmithkline: JohnPatrick Rogers • UC Davis Biotechnology IBM Research, SF: Kristen Beck Program’s Facebook Page International Rice Research Institute, • Twitter (@JKjelstrom, Phillipines: Daniel Caddell @yggdrasil13751, @ Mendota Bioenergy LLC, Fresno: Steve mythodology) icari • LinkedIn Groups: “UCD Biotechnology Monsanto, Calgene Campus: Marta Program” Group, “UC Davis Biotechnology Program Bjornson, Natasha Worden, Hossein Gouran NIH Fellows” Group, Other: Judy Kjelstrom, Denneal Novozymes, Davis, CA: Jonathan Pham, Jamison-McClung, Marianne Hunter Silvia Hilt, Jordan McEwen • Google+ Oculeve, SF: Nithin Dhananjayan • Biotechnology Program’s website OPX Biotechnologies, Inc., Boulder, CO: • DEB website Gabriel Rodriguez • Biotechnology Program’s NIH Training T32 website Seminis Seed, Woodland: Timothy • BioTech System website Butterield • TBC website Small Molecule Discovery Center (SMDC), UCSF: Sucheta Mukherjee Sutro BioPharma, SF: Abigail Yu The Shop Innovation Lab, VSP Global, Sacramento: Meghan Murphy UCD Innovation Access: Nadia Ono US Army Corps of Engineers: Jessica Moore 12 12

BIOTECHNOLOGY EVENT/PICNIC DAY We wish to express our appreciation to all our industry partners for their donations, as well as the DEB graduate students for running the experiments. Industries who donated to the event included: Genentech, Monsanto-Calgene Campus, and Novozymes. This hallmark event has been designed to showcase and celebrate the richness of campus life, the diverse achievements of UCD students, staf and faculty to provide a day of education, information and entertainment to all who attend. The Biotechnology Program Event allows the general public to have a hands-on experience in various biotech-related experiments, including cheese making, DNA extraction, and the new FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG developments for stonewash jeans dye. To see more photos, click on the link for this year’s Our very own DEB students ran all the experiments Picnic Day Biotech Event. and were wonderful UC Davis and DEB ambassadors. Thank you: Johnathon Anderson, Mina Azimi, Kristen Beck, Daniel Caddell, Annie Chiu, Adam Contreras, Maher Elsheikh, Samantha Feng, Jena Gallegos, Doug Gettel, Hyrum Gillespie, Hyun Tae Hwang, Angelica Kowalchuk, Rosanna Kwok, Malgorzata Liro, Alice Martinic, Lucas McKinnon, David Merriam, Akshata Mudinoor, Gulustan Ozturk, Ali Rahimian, Sonia Reveco, Juan Reyes, Cintia Helena Duarte Sagawa, Chelsea Snyder, Allison Stevens, Jessica Stoli, Scott Strobel, Brandon Tautges, Wade Zeno! 13

BioTech SYSTEM NEWS BioTech SYSTEM Update and walking tours for ~200 Academic Year 2014-2015 Northern California high By Denneal Jamison-McClung, PhD school students interested in learning more about life sciences and engineering BioTech SYSTEM is a regional career paths. Many thanks FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG K-14 STEM outreach consortium to the DEB volunteers who administered by the UC Davis prepared “elevator pitch” Biotechnology Program. With talks and led campus tours: deep appreciation for their Hannah Aizad, Brittany generosity, we rely on the volunteer Anderson, Matthew Blain- eforts of Designated Emphasis Hartung, Destiny Davis, in Biotechnology (DEB) doctoral Zachary Fogassy, Jenna students to engage students, teachers and Gallegos, Doug Gettel, Vu Lam, Jeni Lee, Jordan community members in informal science learning. Mancuso, Alice Martinic, David Merriam, Debika DEB students share their passion for scientiic Mitra, Allison Stevens, John Uhrig, Erica Vonasek, discovery and innovation, providing participants Donnelly West, and Eric Zheng. Participating high with the latest information on biotechnology career schools included: American Canyon HS, Antelope paths and research directions. BioTech SYSTEM HS, Colusa HS, Einstein MS (Sacramento), James activities, such as the Teen Biotech Challenge, would Enochs HS (Modesto), Piner HS (Santa Rosa) and not be possible without the support of the region’s Sheldon HS (Elk Grove). business community and biotech industry partners, including Expression Systems, Genentech, Bayer Teen Biotech Challenge CropSciences, Novozymes and Monsanto. The 2015 Teen Biotech Challenge web design competition was a hit with the region’s high In 2014-2015, the BioTech SYSTEM engaged school teachers and students once again. An all- hundreds of California students, teachers and time high of 796 students submitted registrations community members in informal science learning for 414 preliminary websites, with 195 students activities via Biotech Tour Days, HS student and 113 websites advancing to the inal round e-mentoring programs, career fairs, science fairs, of judging by DEB volunteers. Ultimately, special outreach events hosted by collaborators we awarded the 62 winning websites across (e.g. Angels for Hearts, Dinner with A Scientist, seven focus areas: Agricultural Biotechnology; Expanding Your Horizons, Powerhouse Science Computational & Systems Biology; Drug Discovery Center), the annual Teen Biotech Challenge & Biomanufacturing; Environmental Biotechnology; (TBC) web design competition and the Modern Nanobiotechnology; Personal Genomics & Human Farming Workshop for High School Teachers. We Health; and Regenerative Medicine. To view the also teamed up with eminent UC Davis stem cell winning websites, visit http://teenbiotechchallenge. biologists and clinicians, led by Gerhard Bauer, to ucdavis.edu/index.html. ofer Research Scholar Awards to ten of the region’s high school students. Biotech Program staf and DEB volunteers for website judging and event hosting made TBC2015 Biotech Tour Days possible! Many thanks to our team, Marianne Science communication to non-specialist audiences Hunter, Jacki Balderama and Jacqueline Phillips, is a great skill to acquire during grad school and as well as the DEB volunteers. TBC Judges our DEB volunteers had many opportunities to included doctoral student experts across the hone their presentation skills during Biotech Tour seven competition focus areas: Brittany Anderson, Days. In 2014-2015, we hosted biotech seminars Mina Azimi, Kristen Beck, Daniel Caddell, Destiny 14

BioTech SYSTEM NEWS BioTech SYSTEM NEWS (Cont.) Heeney, Hyun Tae Hwang, Malgorzata Liro, Rita Luu, HS each Amory Meltzer, Akshata Mudinoor, Nicole Nozzi, spring. The Esther Shin, David Silberstein, Scott Strobel, Tang mentoring Tang, Denise Trans, Kim Truong, and John Uhrig. TBC programs Event Hosts sacriiced a Friday night (likely of lab last eight research!) to ensure that the award celebration was a weeks and welcoming experience for student winners and their culminate loved ones (for some guests, TBC2015 ofered an with a opportunity for their irst visit to a university campus): mentor- Johnathon Anderson, Liz Anthony, Doug Banda, Cintia mentee Helena Duarte Sagawa, Keith Dunaway, Doug Gettel, mixer. Angelica Kowalchuk, Lauren Matelski, Debika Mitra, E-mentors Chuong Nguyen, Nicole Nozzi, Gulustan Ozturk, in the spring Esther Patchin, Tang Tang, Kim Truong, Toni West, of 2015 Abigail Yu, and Ray Zhang. included: Nicholas Finally, TBC2015 community sponsors of student Aguirre, (Navneet Sandhu, prizes and the award reception were: Bayer Johnathon Research Scholar from Antelope HS) CropScience, Novozymes, Element Realty and the UC Anderson, Davis Biotechnology Program. Leif Anderson, Liz Anthony, Brian Avanzino, Nicole Chafee, Adam Contreras, Amanda Dang, Destiny Research Scholar Awards Davis, Shuchi Desai, Marjannie Eloi, Jenna Gallegos, An ambitious subset of the TBC2015 student Anupama Ganesh, Aiza Go, Dustin Heeney, Silvia participants applied for Research Scholar Awards Hilt, Pui Yan Ho, Gena Hofman, Vicki Hwang, Mittal FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG funded by a California Institute of Regenerative Jasoliya, Alan Sophie Kiss, Rosanna Kwok, Jeni Lee, Medicine (CIRM) Creativity Award. Ten awarded Malgorzata Liro, Alan Lombard, Simon Jesse Lopez, students dedicated their summer vacation to an Amelia Manlove, Lucas McKinnon, Emily Mills, intensive stem cell biology research training program Debika Mitra, Chuong Nguyen, Leslie Nickerson, Alan headed by Gerhard Bauer at the UCDMC Institute for Nguyen, Nicole Nozzi, Juan Reyes, Megan Showalter, Regenerative Cures. The hands-on learning experience Natasha Shrof, Scott Strobel, Linda Su-Feher, Emily culminated in the CIRM Creativity Day research Thompson, Kim Truong, Kacey VanderVorst, Toni conference featuring presentations by trainees West, Sam Westreich, Le Yee, Garrick Yuen, Eric Zheng, from Children’s Hospital Oakland Research Institute and Steve Zicari. (CHORI), City of Hope, Gladstone Institutes, Stanford University, UC Davis, UC San Francisco, UC Santa In addition to e-mentoring, the BioTech SYSTEM Barbara and the University of Southern California. supported regional career fairs, including Douglass MS (Woodland), Lee MS (Woodland) and the regional E-Mentoring & Career Fairs Expanding Your Horizons (EYH)* event for middle DEB volunteers share their personal academic school girls, held at Sacramento State University. journeys, career advice and knowledge of STEM Thanks to DEB volunteers who dedicated time to opportunities with hundreds of high school and middle STEM outreach via career fairs: Ailsa Dalgliesh, Jenna school students in the region every year through Gallegos, Pui Yan Ho, Jeni Lee, Akshata Mudinoor, e-mentoring and career fair participation. Natasha Shrof, Kay Watt and Natasha Worden. In fact, DEB volunteers compose a signiicant Picnic Day & Hands-On Demonstrations fraction of STEM e-mentors recruited by the biotech One of the best ways to learn is by “doing” and many academies at Sheldon HS (Elk Grove) and Vallejo of the DEB students look forward to Picnic Day each 15

BioTech SYSTEM (cont) Pizza Chalk Talks All DEB graduate students are encouraged to present one chalk talk. It is a venue where students interact with courtesy of PHOTO SOURCE other trainees and present their own research work and hear about the research of other DEB students. See below for the list of 2015-2016 Chalk Talks scheduled. FALL 2015 10/7/2015 12:10 FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Justin Thomas (PI: Peter Beal) Chemistry 10/21/2015 12:10 Karan Agrawal (PI: John Newman) Pharmacology & year, when we help hundreds of community members Toxicology extract DNA from strawberries and better understand the use of industrial biotech enzymes in our everyday 11/4/2015 12:10 lives (cheesemaking and textile processing!). All hands Nicole Chafee (PI: Sheila David) Chemistry on deck for Picnic Day 2015 included our reagent/supply preparation crew: Annie Chiu, Jenna Gallegos, Alice 12/2/2015 12:10 Martinic, Gulustan Ozturk, Chelsea Snyder and Wade Natasha Worden (PI: Georgia Drakakaki) Plant Biology Zeno. Teaching the ine art of pipetting and running the experimental stations at the event were: Johnathon WINTER 2016 1/27/2016 11:10 S Anderson, Mina Azimi, Kristen Beck, Daniel Caddell, Sana Vaziri (PI: Sharon Aviran) Computer Science Adam Contreras, Cintia Helena Duarte Sagawa, Maher Elsheik, Samantha Feng, Doug Gettel, Hyrum Gillespie, 2/3/2016 11:10 Hyun Tae Hwang, Angelica Kowalchuk, Rosanna Kwok, Christopher Chapman (PI: Erkin Seker) Biomedical Malgorzata Liro, Lucas McKinnon, David Merriam, Engineering Akshata Mudinoor, Ali Rahimian, Sonia Reveco, Juan Reyes, Allison Stevens, Jessica Stoli, Scott Strobel, and 2/24/2016 11:10 Brandon Tautges. Chandrima Majumdar (PI: Sheila David) Chemistry SPRING 2016 4/6/2016 12:10 For more information on the BioTech SYSTEM, check Scott Strobel (PI: Tina Jeoh) Biological Systems Eng. out the latest happenings on our website http:// biotechsystem.ucdavis.edu/. 4/20/2016 12:10 Adam Contreras (PI: Min Zhao) Biochemistry, Molecular, Cellular & Developmental Biology 4/27/2016 12:10 Jenna Harvestine (PI: Kent Leach) Biomedical Engin. 5/4/2016 12:10 Nicole Nozzi (PI: Shota Atsumi) Chemistry 5/18/2016 12:10 David Merriam (PI: Dennis Hartigan-O’Connor) Microbiology 16

MCB/ECH 294 SEMINAR SERIES FALL BIOTECH FRIDAY SEMINARS, MCB/ECH 294 (OPEN TO THE PUBLIC) FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG 17 17

MIC 292 FROM DISCOVERY TO PRODUCT with Dr. Judy Kjelstrom) for the wonderful tour and real-world biomanufacturing information provided during the course. FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG This course is designed to provide a unique opportunity to gain insight into basic and applied biotechnology at the industrial level. Lectures will be presented by senior scientists/engineers from Novozymes, Inc. in Davis California. Appropriate for graduate students in all areas of biology, engineering and agriculture, especially those in the Designated Emphasis in Biotechnology Program. MIC 292 is an approved seminar elective for the DEB program. MIC 292, held every other winter quarter, commences This seminar series is open to the public and will be with a tour of the Novozymes site. We are very grateful ofered Winter quarter, 2016. to the director, Dr. Debbie Yaver (co-instructor along 18

MIC 292 FROM DISCOVERY TO PRODUCT MARK YOUR CALENDARS MARK YOUR CALENDARS: 2016 February 15 Retreat Attendance Forms Due February 22 Retreat Abstracts & Oral Presentations Due March 5 25th Annual Biotechnology Training Retreat in Napa FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG April 16 Picnic Day: Biotech Event in 148 Briggs Hall April 22 NIH Biotech Training Grant Fellowship Applications Due 20 AnnualTeenBiotechChallenge May July ~25 - 29 Flow Cytometry Course August ~8 – 12 Proteomics Course 19

BIOTECHNOLOGY PROGRAM CONTACTS FOR MORE GRAPHIC DESIGN FREEBIES: VISIT WWW.DESIGNFREEBIES.ORG Biotechnology Program Contact Information Judith A. Kjelstrom, Ph.D. Denneal Jamison-McClung, PhD Director Associate Director [email protected] [email protected] PRESORTED (530) 752-8228 (530) 752-5090 STANDARD U.S. POSTAGE PAID Marianne Hunter Jacki Balderama PERMIT NO. 123 Assistant Director, Administration Event Manager [email protected] [email protected] (530) 752-8183 (530) 752-1048 Jacqueline Phillips Kelly Meade Program Associate Budget Analyst [email protected] [email protected] (530) 752-3260 (530) 752-8183