USP Listing

Customer Service About Canadian Life Science Au suject de Canadian Life Science Founded in 1997, Canadian Life Science (CLS) has steadily grown Fondée en 1997, Canadian Life Science (CLS) n’a cessé de croître to Canada’s leading supplier of LC/GC columns, chromatography pour devenir un chef de file canadien dans la vente de colonnes and dissolution accessories as well as 2d long-term sample HPLC / GC, d’accessoires de chromatographie et dissolution, storage tubes and racks for bio-banking and compound ainsi que dans la vente de tubes et systèmes d’entreposage long management. terme pour échantillons. For over 22 years, CLS has provided customers with unparalleled Depuis plus de 22 ans, CLS offre à ses clients un service et service, expertise and a wide selection of quality and cost- une expertise inégalés, en plus d’un large éventail de produits effective products that offer maximum flexibility to solve your économiques de qualité offrant une flexibilité maximale afin de analytical challenges. CLS is your foundation for what matters. résoudre vos problèmes analytique. CLS est votre pilier pour ce qui compte. Everyone is accessible to you Nous sommes très accessible We believe that our customers like our personal touch. Nous avons une approche personnelle et nous répondons à tous We take your calls personally, not a computer, not voicemail . les appels lorsque vous téléphonez au bureau chef. Nous n’avons We have dedicated inside customer service staff who care, and pas de boîte vocale. take care for specific areas. We have knowledgeable outside staff Notre personnel est dévoué au service à la clientèle et ce à based in most of the larger cities accross Canada. travers le Canada. Si vous désirez parler directement à notre We supply world class products Directrice de comptes au Québec, vous pouvez contacter Canadian Life Science distributes for top-quality manufacturers. Genevieve Lemieux au 514.428.8034. Our product offering has been chosen in a way that will give you Nous choisissons les meilleurs produits au monde the maximum flexibility solving your analytical challenges. En tant que distributeur nous avons l’avantage de choisir les Technical Support meilleurs fournisseurs et notre gamme complète de produit vous Our technical staff is happy to respond to customer enquiries. donne l’embarras du choix. We can also supply extensive application information from one Support Technique of the world’s largest data bases. Notre équipe technique se fait toujours un plaisir de vous aider à Plan the best delivery faire le meilleur choix pour vos applications. When you decide to purchase a product from Canadian Life Service et logistique Science our customer service department will find the fastest Lorsque vous placez une commande chez nous, nous nous and most economical way to send your order to you. For assurons de choisir le moyen le plus efficace et économique your convenience we have two warehouse locations, one in d’acheminer la marchandise. Edmonton, AB and one in Peterborough, ON. Nous avons deux entrepôts dont un en Alberta pour servir nos We’re glad to help clients de l’Ouest et un en Ontario pour servir nos clients de l’Est. We are never too busy to take your call. C’est un plaisir de vous servir Try us. You’ll notice the difference. Nous ne sommes jamais trop occupés pour vous répondre. Canadian Life Science, friendly people to do business with! Essayez-nous et vous verrez la différence. Il est agréable de faire affaire avec nous! I-22 CANADIAN Proud member of the Chrom4 buying group Fier membre du groupe dʼacheteur Chrom4 LIFE SCIENCE 1 888-226-2775 :: [email protected] :: www.lifescience.ca

Guide pour la Sélection de Colonnes HPLC/UHPLC Guide pour la Sélection de Colonnes HPLC/UHPLC USP Chromatographic Columns Listing Description Our Brand L1 Octadecyl silane (ODS or C18) chemically bonded to porous or non-porous silica or ceramic micro-particles, ACE C18, ACE Excel C18, ACE SuperC18, ACME C18, 1.5 to 10 µm in diameter, or a monolithic rod ACME F5/C18, ACME AMIDE/C18, ACME PLUS, HALO C18, HALO Peptide ES-C18, Inertsil (ODS, ODS-2, ODS-3, ODS-4, L2 Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid ODS-SP) Inertsil ODS-P, Inertsil ODS-HL InertSustain C18, spherical core, 30 to 50 µm in diameter InertSustain AQ-C18, InertSustainSwift C18 Grace Alltech Pellicular C18, ECONO PREP ODS L3 Porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod ACE Silica, ACME Silica, HALO HILIC, Inertsil SIL-100Å, Inertsil SIL-150Å, Inertsil WP300-SIL L4 Silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50 µm in diameter Grace Alltech Pellicular Silica, ECONO PREP SIL L5 Alumina of controlled surface porosity bonded to a solid spherical core, 30 to 50 µm in diameter Please enquire L6 Strong cation-exchange packing-sulphonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 µm Adsorbosphere XL SCX, Partisil SCX in diameter L7 Octylsilane (C8) chemically bonded to totally or superficially porous silica particles, 1.5 to 10 µm in diameter, ACE C8, ACE Excel C8, ACME C8, HALO C8, Inertsil (C8, C8-3, or a monolithic silica rod C8-4), InertSustain C8, InertSustainSwift C8 L8 An essentially monomolecular layer of aminopropylsilane (NH2) chemically bonded to totally porous silica gel Inertsil NH2, InertSustain NH2 support, 1.5 to 10 µm in diameter, or a monolithic silica rod. L9 Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, Inertsil CX, Partisil SCX, Partisphere SCX 3 to 10 µm in diameter L10 Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod ACE CN, ACE Excel CN-ES, ACME CN, HALO ES-CN, HALO Peptide ES-CN, Inertsil CN-3, InertSustain Cyano ACE Phenyl, ACE Excel Phenyl, ACME Phenyl, HALO Biphenyl, L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod HALO Diphenyl, HALO Phenyl-Hexyl, Inertsil (Ph, Ph-3), InertSustain Phenyl, InertSustain Phenylhexyl L12 A strong anion-exchange packing made by chemically bonding a quartenary amine to a solid silica spherical core, Pellicular SAX 30 to 50 µm in diameter L13 Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diameter Adsorbosphere TMS, Adsorbosphere XL C1, Allsphere C1, APEX C1 L14 Silica gel having a chemicallly bonded strongly basic quaternary ammonium anion-exchange coating, 5 to 10 µm Adsorbosphere SAX, Adsorbosphere XL SAX, Allsphere SAX, in diameter Macrosphere 300 SAX, Inertsil AX, Nucleosil SB, Partisil SAX, Partisphere SAX, Platinum SAX, Vydac 3021C 20 CANADIAN 1 888-226-2775 :: [email protected] :: www.lifescience.ca LIFE SCIENCE

HPLC/UHPLC Column Selection Guide USP Chromatographic Columns Listing Description Our Brand L15 Hexylsilane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter Allsphere C6, Chomegabond C6, Grom-Sil Hexyl-1 HPLC/UHPLC Column Selection Guide L16 Dimethylsilane chemically bonded to porous silica particles, 5 to 10 µm in diameter Adsorbil C2, Chromegabond C2, Nucleosil C2, Polygosil C2 Alltech OA-1000, Alltech OA-2000, Alltech IOA-1000, Alltech IOA- L17 Strong cation-exchange resin consisting of sulphonated cross-linked styrene-divinylbenzene copolymer in the 2000, Hamilton HC-75H, Hamilton PRP-X200, Hamilton PRP-X300, hydrogen form, 6 to 12 µm in diameter Nucleogel Sugar 810H, Nucleogel ION 300 OA, Shodex IC Y-521, Shodex RSpak KC-811, Shodex SUGAR SH1011, Shodex SUGAR SH1821, Shodex SC1011, Shodex SC1211, Shodex SC1821 L18 Amino and cyano groups chemically bonded to porous silica particles, 3 to 10 µm in diameter Adsorbosphere PAC, Chromegabond A/CN, Legacy L18, Partisil 10 PAC, Partisphere PAC Hamilton HC-40,Hamilton HC-75 Ca, Nucleogel Sugar Ca, L19 Strong cation-exchange resin consisting of sulphonated cross-linked styrene-divinylbenzene copolymer in the Nucleogel Sugar 810 Ca, Shodex SUGAR SC1011, calcium form, 5 to 15 µm in diameter Shodex SUGAR SC1211, Shodex SUGAR SC1821, Shodex USPpak MN-431 L20 Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5 to 10 µm in diameter, or a Inertsil Diol, Nucleosil Diol, Shodex PROTEIN KW-800 series, monolithic silica rod Shodex KW-400 series Nucleogel RP, Shodex RSpak DS-413, Shodex RSpak DS-613, L21 A rigid, spherical styrene-divinylbenzene copolymer, 3 to 30 µm in diameter Shodex RSpak RP18-413, Shodex RSpak RP18-415, Shodex RSpak RP18-613 Alltech Anion Exclusion, Nucleogel SCX, Shodex CXpak P-421S, Shodex IC Y-521, Shodex RSpak DC-613, Shodex RSpak KC-811, L22 A cation-exchange resin made of porous polystyrene gel with sulfonic acid groups, 5 to 15 µm in diameter Shodex SUGAR KS-800 series, Shodex SUGAR SC1011, Shodex SUGAR SC1211,Shodex SUGAR SC1821, Shodex SUGAR SP0810, Shodex SUGAR SZ5532, Shodex USPak MN-431 L23 An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quartenary ammonium groups, Allsep, Nucleogel SAX, Shodex IEC QA-825 7 to 12 µm in size L24 Polyvinylalcohol chemically bonded to porous silica particles, 5 µm in diameter Please enquire Packing having the capacity to separate compounds with a molecular weight range from 100-5000 Da(as deter- L25 mined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers. A polymethacrylate Shodex OHpak SB-802HQ, Shodex OHpak SB-802.5HQ, resin base, cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups) Shodex SB402.5 was found suitable ACE C4-300, ACE C4, ACE Excel C4, HALO Protein C4, Inertsil L26 Butyl silane chemically bonded to totally porous or superficially porous silica particles, 1.5 to 10 µm in diameter C4, Inertsil WP300-C4, Vydac 214ATP, Vydac 214MS, Vydac 214TP, Vydac C4 L27 Porous silica particles, 30 to 50 µm in diameter Daisogel L28 A multifunctional support, which consists of a high purity, 60 Å, spherical silica substrate that has been bonded with Alltech mixed mode C8/anion, Legacy L28, ProTec C8 a cationic exchanger, sulfonic acid functionality in addition to a convention reversed phase C8 funcionality 1 888-226-2775 :: [email protected] :: www.lifescience.ca CANADIAN 21 LIFE SCIENCE

Guide pour la Sélection de Colonnes HPLC/UHPLC Guide pour la Sélection de Colonnes HPLC/UHPLC USP Chromatographic Columns Listing Description Our Brand L29 Gamma alumina, reverse-phase, low carbon percentage by weight, alumina-based polybutadiene spherical par- Gammabond ARP-1, Gammabond Alumina Potency ticles, 5 µm in diameter with a pore volume of 80 Å L30 Ethyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter APEX Prepsil C2, Chromegabond C2-E, Nucleosil C2 A hydroxide selective, strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core Please enquire L31 of 8.5 µm macroporous particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with CHIRALPAK WH, Nucleosil Chiral-1 55% divinylbenzene L32 A chiral ligand-exchange resin packing-L-proline copper complex covalently bonded to irregularly shaped silica particles, 5 to 10 µm in diameter L33 Packing having the capacity to separate dextrans by molecular size over a range of 4,000 to 500,000 Da. It is spheri- Inertsil WP 300 Diol, Macrosphere 150Å, Shodex PROTEIN cal, silica-based, and processed to provide pH stability KW-800 series, Shodex KW-400 series L34 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead Nucleogel Sugar Pb, Shodex SUGAR SP0810 form, 7 to 9 µm in diameter L35 A zirconium-stabilized spherical silica packing with a hydrophilic (diol-type) molecular monolayer bonded phase Please enquire having a pore size of 150 Å L36 A 3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5 µm aminopropyl silica L-Phenylglycine, Nucleosil Chiral-3 L37 Packing having the capacity to separate proteins by molecular size over a range of 2,000 to 40,000 Da. It is a Shodex OHpak SB-803 HQ, Shodex SB403-4E polymethacrylate gel L38 A methacrylate-based size-exclusion packing for water-soluble samples Shodex SB400 series, Shodex OHpak SB-800HQ series L39 A hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin Shodex SB400 series, Shodex OHpak SB-800HQ series, Shodex ODP2 HP, Shodex RSpak DM-614 L40 Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles, 3 to 20 µm in diameter CHIRALCEL OD, CHIRALCEL OD-H L41 Immobilized 1-acid glycoprotein on spherical silica particles, 5 µm in diameter CHIRALPAK AGP L42 Octylsilane and octadecylsilane groups chemically bonded to porous silica particles, 5 µm in diameter Chromegabond PSC, HiChrom RPB 22 CANADIAN 1 888-226-2775 :: [email protected] :: www.lifescience.ca LIFE SCIENCE

HPLC/UHPLC Column Selection Guide USP Chromatographic Columns Listing Description Our Brand L43 Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 1.5 to 10 µm in diameter ACE C18-PFP, ACME F5/C18, HALO PFP, HPLC/UHPLC Column Selection Guide InertSustain PFP, NUCLEODUR PFP, L44 A multifunctional support, which consists of a high purity, 60 Å, spherical silica substrate that has been bonded with NUCLEOSHELL PFP a cationic exchanger, sulfonic acid functionality in addition to a convention reversed phase C8 funcionality Chromegabond RP-SCX, Legacy L44 L45 Beta cyclodextrin, R,S-hydroxypropyl ether derivative, bonded to porous silica particles, 3 to 10 µm in diameter Nucleodex Beta OH, Nucleodex Beta PM, Shodex ORpak CDBS-453 L46 Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads, Please enquire about 9 to 11 µm in diameter L47 High capacity anion-exchange microporous substrate, fully functionalized with a trimethylamine group, Hamilton PRP-X100, Hamilton PRP-X110, Hamilton RCX-10, 8 µm in diameter Hamilton RCX-30 L48 Sulphonated, cross-linked polystyrene with an outer layer of submicron, porous, anion-exchange microbeads, 5 to Please enquire 15 µm in diameter L49 A reversed-phase packing made by coating a thin layer of polybutadiene on to spherical porous zirconia particles, 3 Please enquire to 10 µm in diameter Please enquire Multifunction resin with reverse-phase retention and strong anion-exchange functionalities. The resin consists of L50 ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 µm in diameter, and a surface area of not less than 350 m2/g. Substrate is coated with quartenary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene L51 Amylose tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 3 to 10 µm in diameter CHIRALPAK AD, CHIRALPAK AD-H, CHIRALPAK AD-3 L52 A strong cation exchange resin made of porous silica with sulfopropyl groups, 5 to 10 µm in diameter Please enquire Please enquire Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to Please enquire L53 15 µm diameter. Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers. Universal Cation, Universal Cation HR Please enquire Capacity not less than 500 µEq/column L54 A size exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads, 5 to 15 µm in diameter L55 A strong cation exchange resin made of porous silica coated with polybutadiene-maleic acid copolymer, about 5 µm in diameter L56 Propyl silane chemically bonded to totally or superficially porous silica particles, 3 to 10 µm in diameter 1 888-226-2775 :: [email protected] :: www.lifescience.ca CANADIAN 23 LIFE SCIENCE

Guide pour la Sélection de Colonnes HPLC/UHPLC Guide pour la Sélection de Colonnes HPLC/UHPLC USP Chromatographic Columns Listing Description Our Brand L57 A chiral-recognition protein, ovomucoid, chemically bonded to silica particles, about 5 µm in diameter, with a pore Please enquire size of 120 Å NUCLEOGEL Sugar Na, Shodex CXpak P-421S, Shodex RSpak L58 Strong cation-exchange resin consisting of sulphonated cross-linked styrene-divinylbenzene copolymer in the DC-613, Shodex SUGAR KS-801, Shodex SUGAR KS-802, Shodex sodium form, about 6 to 30 µm diameter SUGAR KS-803, Shodex SUGAR KS-804, Shodex SUGAR KS-805, Shodex SUGAR KS-806, Shodex SUGAR KS-807 L59 Packing for the size-exclusion separations of proteins (separation by molecular weight) over the range of 5 to 7000 Shodex KW400 series, Shodex PROTEIN KW-800 series kDa. The packing is spherical 1.5 to 10 µm, silica or hybrid packing with a hydrophilic coating L60 Spherical, porous silica gel, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl ACME Amide/C18, HALO RP-Amide, Nucleodur PolarTec, amide groups and endcapped Nucleosil C18 Nautilus A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 13 µm microporous L61 particles having a pore size less than 10 units and consisting of ethylvinylbenzene cross-linked with 55% divinylben- Please enquire zene with a latex coating composed of 85 nm diameter microbeads bonded with alkanol quarternary ammonium ions (6%) L62 C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter Chromegabond C30 L63 Glycopeptide teicoplanin linked through multiple covalent bonds to a 100 Å spherical silica Please inquire L64 Strongly basic anion exchange resin consisting of 8% crosslinked styrene divinylbenzene copolymer with a Please enquire quartenary ammonium group in the chloride form, 45 to 180 µm in diameter Please enquire L65 Strongly acidic cation exchange resin consisting of 2% sulfonated crosslinked styrene divinylbenzene copolymer with a sulfonic acid group in the hydrogen form, 63 to 250 µm in diameter L66 A crown ether coated on a 5 µm particle size silica gel substrate. The active site is (S)-18-crown-6-ether CROWNPAKTM CR (+) L67 Porous vinyl alcohol copolymer with a C18 alkyl group attached to the hydroxyl group of the polymer, 2 to 10 µm in Shodex Asahipak ODP-40, Shodex Asahipak ODP-50, diameter Shodex ET-RP1 L68 Spherical, porous silica, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl InertSustain Amide, Inertsil Amide amide groups and not endcapped L69 Ethylvinylbenzene/divinylbenzene substrate agglomerated with quaternary amine functionalized 130 nm latex Please enquire beads, about 6.5 µm in diameter L70 Cellulose tris(phenyl carbamate) coated on 5 µm silica CHIRALCEL OC-H 24 CANADIAN 1 888-226-2775 :: [email protected] :: www.lifescience.ca LIFE SCIENCE

HPLC/UHPLC Column Selection Guide USP Chromatographic Columns Listing Description Our Brand L71 A rigid, spherical polymetacrylate, 4 to 6 µm in diameter Shodex RSpak DE-213, Shodex RSpak DE-413, HPLC/UHPLC Column Selection Guide Shodex RSpak DE-613 L72 (S)-phenylglycine and 3,5-dinitroaniline urea linkage covalently bonded to silica Please enquire L73 A rigid, spherical polydivinylbenzene particle, 5 to 10 µm in diameter Jordi Resolve DVB Please enquire A strong anion-exchange resin consisting of a highly cross-linked core of 7 µm macroporous particles having a Resolvosil BSA L74 100 Å average pore size and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene and an anion- Please enquire Please enquire exchange layer grafted to the surface, which is functionalized with alkyl quartenary ammonium ions Primesep D, Primesep SB, Primesep B2 L75 A chiral-recognition protein, bovine serum albumin (BSA), chemically bonded to silica particles, about 7 µm in CHIRALPAK AS-H diameter, with a pore size of 300 Å L76 Silica based weak cation-exchange material, 5 µm in diameter. Substrate is surface polymerized polybutadiene- maleic acid to provide carboxylic acid functionalities. Capacity not less than 29 µEq/column Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 6 to L77 9 µm diameter. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity not less than 500 µEq/column (4 mm x 25 cm) A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and anion-exchange (primary, L78 secondary, or tertiary amino groups) functional groups chemically bonded to porous or non-porous or ceramic micro-particles, 1 to 50 µm in diameter or a monolithic rod L79 A chiral-recognition protein, human serum albumin (HSA), chemically bonded to silica particles, about 5 µm in diameter L80 Cellulose tris(4-methylbenzoate)-coated, porous, spherical, silica particles, 5 to 20 µm in diameter CHIRALCEL OJ, CHIRALCEL OJ-H, CHIRALCEL OJ-3 A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 9 µm porous particles L81 having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex Please enquire coating composed of 70 nm diameter microbeads (6% crosslinked) bonded with alkanol quartenary ammonium ions L82 Polyamine chemically bonded to cross-linked polyvinyl alcohol polymer, 4 to 5 µm in diameter Shodex Asahipak NH2P-40, Shodex Asahipak NH2P-50 A hydroxide-selective, strong anion-exchange resin-quartenary amine bonded on latex particles attached to a core Please enquire L83 of 10.5 µm microporous particles having a pore size of 10 Å and consisting of ethylvinylbenzene cross-linked with Please enquire 55% divinylbenzene. Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 5 µm L84 diameter. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity not less than 8400 µEq/column (5 mm x 25 cm) 1 888-226-2775 :: [email protected] :: www.lifescience.ca CANADIAN 25 LIFE SCIENCE

Guide pour la Sélection de Colonnes HPLC/UHPLC Guide pour la Sélection de Colonnes HPLC/UHPLC USP Chromatographic Columns Listing Description Our Brand L85 A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and weak cation-exchange Primesep 100, Primesep 200, Primesep C, Primesep 500 (carboxyl groups) functional groups chemically bonded to porous or non-porous particles, 1 to 50 µm in diameter L86 A 5 µm fused core particle with a highly polar ligand possessing 5 hydroxyl groups tethered to the silica gel Halo Penta-HILIC outer layer L87 Dodecyl silane chemically bonded to porous silica particles, 1.5 to 10 µm in diameter Please enquire L88 Glycopeptide vancomycin linked through multiple covalent bonds to 100 Å spherical silica Please enquire Packing having the capacity to separate compounds with a molecular weight range from 100 – 3000 Da (as deter- Please enquire L89 mined by polyethylene oxide), applied to neutral and anionic water-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylate ether (surface contains some residual cationic functional groups) L90 Amylose tris-[(S)-alpha-methylbenzylcarbamate] coated on porous, spherical silica particles, 3 to 10 µm in diameter CHIRALPAK AS, CHIRALPAK AS-H, CHIRALPAK AS-3 L91 Strong anion-exchange resin consisting of monodisperse porous polystyrene/divinyl benzene beads coupled with Please enquire quartenary amine. Bead size is 3 to 10 µm Please enquire CHIRACEL OD-RH, CHIRACEL OD-3R A strong anion-exchange resin consisting of a highly cross-linked core of 5 – 9 µm macroporous particles having Please enquire L92 a 100 Å average pore size and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene and an anion Halo Penta-HILIC InertSustain AQ-C18 exchange layer grafted to the surface, which is functionalized with alkanol quartenary ammonium ions Please enquire Please enquire L93 Cellulose tris(3,5-dimethylphenylcarbamate) reversed phase chiral stationary phase coated on 3 or 5 µm silica gel particles L94 A strong anion-exchange resin consisting of a highly crosslinked 15 µm microporous particles functionalized with very low crosslinked latex (0.5%) to provide alkanol quartenary ammonium ion exchange sites L95 Highly polar alkyl ligand comprising five hydroxyl groups that are chemically bonded to totally porous or superficially porous silica or a monolithic silica rod Alkyl chain, reversed-phase bonded to totally porous or superficially porous silica designed to retain hydrophilic L96 and other polar compounds when using highly aqueous mobile phases, including 100% aqueous, 1.5 µm to 10 µm in diameter Weak cation-exchange resin consisting of a highly cross-linked core of 5.5 µm porous particles having a pore size of L97 2000 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity not less than 2400 µEq/column (4 mm x 25 cm) Weak cation-exchange resin consisting of a highly cross-linked core of 8 µm microporous particles having an aver- L98 age pore size of 10 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. Substrate is surface grafted with carboxylic acid functionalized groups. Capacity not less than 46 µEq/column (4 mm x 5 cm) 26 CANADIAN 1 888-226-2775 :: [email protected] :: www.lifescience.ca LIFE SCIENCE

HPLC/UHPLC Column Selection Guide USP Chromatographic Columns Listing Description Our Brand L99 Amylose tris-(3,5-dumethylphenylcarbamate), immobilized on porous, spherical, silica particles, 3 to 5 µm in CHIRALPAK IA, CHIRALPAK IA-3 HPLC/UHPLC Column Selection Guide diameter Please enquire A 55% crosslinked, microporous, hydrophobic resin core (9 µm microporous particles having a pore size of 10 Å) Cosmocore Cholester, Cosmosil Cholester L100 that consists of a bilayer of anion and cation exchange latex. The first layer is fully sulfonated (140 nm) and the (S,S) Whelk-O 1 Please enquire second layer is fully aminated (76 nm) Please enquire Please enquire L101 Cholesteryl groups chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 µm in Please enquire diameter, or a monolithic rod CHIRALCEL OJ-RH L102 (Naproxen, (S,S)Whelk-O 1) 1-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophenanthrene covalently bonded to porous CHIRALPAK CBH spherical silica particles, 5 to 10 µm in diameter Please enquire A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 7.5 μm porous Please enquire L103 particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene Please enquire Please enquire electrostatically bonded with hyperbranched alkanol quaternary ammonium ions L104 Triazole groups chemically bonded to porous silica particles, 1.5 to 10 μm in diameter L105 A strong anion-exchange resin consisting of a highly cross-linked 9 μm super macroporous (2000 Å) particles functionalized with very low cross-linked latex (0.2%) to provide alkyl quaternary ammonium ion sites Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, L106 5 to 8 μm diameter, macroporous particles having an average pore size of 100 Å. Substrate is surface grafted with carboxylic acid and phosphonic acid functional groups. Capacity not less than 2800 μEq/column (4 mm x 25 cm) L107 Cellulose tris(4-methylbenzoate)-coated porous spherical particles, 3 to 5 μm in diameter, for use with reversed-phase mobile phases L108 A chiral-recognition protein, cellobiohydrolase (CBH), chemically bonded to silica particles, about 5 μm in diameter L109 Spherical particles of porous graphitic carbon, 3 to 30 μm in diameter L110 A strong anion-exchange resin consisting of a highly cross-linked 13 μm microporous (less than 10 Å) particles coated with very low cross-linked latex (0.5%) to provide alkanol quaternary ammonium ion exchange sites L111 Polyamine chemically bonded to porous spherical silica particles, 5 μm in diameter A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 8.5 μm porous L112 particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65 nm diameter microbeads (5% cross-linked) bonded with alkanol quaternary ammonium ions 1 888-226-2775 :: [email protected] :: www.lifescience.ca CANADIAN 27 LIFE SCIENCE

Guide pour la Sélection de Colonnes HPLC/UHPLC Guide pour la Sélection de Colonnes HPLC/UHPLC USP Chromatographic Columns Listing Description Our Brand L113 A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 7.5 μm porous Please enquire particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene SeQuant ZIC-HILIC with a latex coating composed of 65 nm diameter microbeads (8% cross-linked) bonded with alkanol quaternary Please enquire ammonium ions Please enquire CROWNPAK CR(-) L114 Sulfobetaine graft-polymerized to totally or superficially porous silica, 1.5 to 10 μm in diameter, or a monolithic rod. ACME™ PAH, NUCLEODUR C18 PAH Packing having densely bonded zwitterionic groups with 1:1 charge balance. CHIRALPAK IC, CHIRALPAK IC-3` Please enquire L115 Ethylvinylbenzene/divinylbenzene substrate (55% cross-linked) agglomerated with quaternary amine functionalized Please enquire 275 nm latex microbeads (6% cross-linked), about 8.5 µm in diameter CHIRALCEL OD-R Please enquire L116 Sulfonated ethylvinylbenzene/divinylbenzene substrate agglomerated with hydrophilic quaternary amine COSMOSIL PYE functionalized glycidyl-derivative methacrylate microbeads, approximately 2 to 50 μm in diameter CHIRALPAK IC, CHIRALPAK IC-3 Please enquire L117 A crown ether coated on a 5 μm particle size silica gel substrate. The active site is (R)-18-crown-6-ether L118 Aqueous polymerized C18 groups on silica particles, 1.2 to 5 μm in diameter L119 Cellulose tris-(3,5-dichlorophenylcarbamate), immobilized on porous, spherical, silica particles, 3 to 5 µm in diameter A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 13 µm microporous L120 particles having a pore size of less than 10 Å units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65 nm diameter microbeads (8% crosslinked) bonded with alkanol quaternary ammonium ions. Capacity not less than 10 mEq/column (4 mm x 5 cm) L## Ethylhexyl triazone, FluoFix – Fluorocarbon chains chemically bonded to 5 μm spherical silica particles L## Lanatoprost, Chiracel OD-R – Cellulose tris(3,5-dimethylphenylcarbamate) coated on 10 μm silica gel particles Polyethylene Glycol 3350, Aquagel OH 40 – Packing having the capacity to separate compounds with a molecular L## weight range from 10,000 to 200,000 g/mol (as determined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers, composed of a rigid macroporous material with a hydrophilic surface L## Felodipine Extended-release Tablets, COSMOSIL PYE – Pyrenyl groups chemically bonded to porous silica particles, 1.5 to 10 μm in diameter, or a monolithic rod L## Atomoxetine Hydrochloride, Chiralpak IC – Cellulose tris-(3,5-dichlorophenylcarbamate), immobilized on porous, spherical, silica particles, 3 to 5 μm in diameter Sodium Nitrite, IonPac AS12A – A strong anion-exchange resin consisting of a highly cross-linked 9 μm L## supermacroporous (2000 Å) particles functionalized with very low cross-linked latex (0.2%) to provide alkyl quartenary ammonium ion sites 28 CANADIAN 1 888-226-2775 :: [email protected] :: www.lifescience.ca LIFE SCIENCE

HPLC/UHPLC Column Selection Guide USP Chromatographic Columns Listing Description Our Brand L## Liquid Glucose, Aminex HPX-42A – Strong cation-exchange resin consisting of sulfonated cross-linked Please enquire HPLC/UHPLC Column Selection Guide styrene-divinylbenzene copolymer in the silver form, average 9 μm in diameter CHIRALCEL OJ-RH L## Rosuvastatin Calcium, Chiracel OJ-RH – Cellulose tris(4-methylbenzoate)-coated porous spherical particles, Please enquire 3 to 5 μm in diameter, for use with reversed phase mobile phases Cosmosil HILIC Please enquire L## Palonosetron Hydrochloride, Chirobiotic-V – Glycopeptide vancomycin linked through multiple covalent bonds Please enquire to 100 Å spherical silica Please enquire Please enquire L## Allantoin, Cosmosil HILIC – Triazol groups chemically bonded to porous silica particles, 1.5 to 10 μm in diameter Please enquire EPTACOG alfa, Dionex CarboPac PA100 – Ethylvinylbenzene/divinylbenzene substrate (55% cross-linked) L## agglomerated with quartenary amine functionalized 275 nm latex microbeads (6% cross-linked), about 8.5 μm in diameter EPTACOG alfa, Dionex DNAPac PA100 – Sulfonated ethylvinylbenzene/divinylbenzene substrate approximately L## 12 to 14 μm in diameter agglomerated with hydrophilic quartenary amine functionalized glycidyl-derivative methacrylate microbeads Adenosine, Dionex IonPac CS12A and CG12A - Weak cation-exchange resin consisting of ethylvinylbenzene, L## 55% cross-linked with divinylbenzene copolymer, 5 to 8 μm diameter, macroporous particles having an average pore size of 100 Å. Substrate is surface grafted with carboxylic acid and phosphonic acid functional groups. Capacity not less than 2800 μEq/column (4 mm x 25 cm) Adenosine, Dionex IonPac AG18 - A hydroxide-selective, strong anion-exchange resin consisting of a highly L## crosslinked core of 13 μm microporous particles having a pore size of <10 Å and consisting of ethylvinylbenzene crosslinked with 55% divinylbenzene with a latex coating composed of 65 nm diameter microbeads (8% crosslinked) bonded with alkanol quartenary ammonium ions. Capacity not less than 10 μEq/column (4 mm x 5 cm) Adenosine, Dionex IonPac AS18 - A hydroxide-selective, strong anion-exchange resin consisting of a highly cross-linked core of 7.5 μm macroporous particles having an average pore size of 2000 Å and consisting of L## ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 65 nm diameter microbeads (8% crosslinked) bonded with alkanol quartenary ammonium ions. Capacity not less than 285 μEq/column (4 mm x 25 cm) 1 888-226-2775 :: [email protected] :: www.lifescience.ca CANADIAN 29 LIFE SCIENCE