Ispectrum magazine #16

ISPECTRUMIssue 16/March-April 2016 MAGAZINEThe Chemistry ofStress:How It Affects Our Health?i ,the alien ImmunohistologyWhy Emotions Influence 6our Immune System

CONTENTS Features 13 273 03 07 The Chemistry of Stress: How It Affects Our Health? 04 what exactly happens in our body when we undergo stress? 06 Negative thoughts impact badly on our body 07 Negative effects of adrenaline on the body 13 I, the Alien 15 The superior ability of the human body 22 Our body detects radio frequen- cy signals from the surrounding space 27 Why Emotions Influence our Immune System Healing Autoimmune Disorders with NLP 30 Reprogramming the negative emotions 33 33 Immunohistology: Antibodies show us diseased cells 35 Targeted synthesizing of anti- bodies 37 Multiple advantages in contrast to gene sequencing 1

editorialDear Readers, Mado MartinezMarch is my favourite month of the year. Editorial DirectorSpring is here, with its sudden changesof weather, and issue 16 keeps the same Ispectrumspirit. As always, Dr. Fahad Basheer,author of The Science of Emotions, has magazinewritten two pieces of special interest.The first one digs into the Chemistry Published Bimonthly ISSN 2053-1869of stress to show us how it affects ourhealth, whilst the second shows us how Editorial Directoremotions influence our immune system. Mado Martinez, [email protected] Engineer Dimitre Assenov offers usthe reading of his latest scientific paper Art Directorunder the intriguing title: “I, the Alien”. Rayna PetrovaAre we out of place in this planet? You [email protected] find the answer here. Contributing EditorsAnd Markus Köller comes with an inter- Matt Lovedayesting approach to antibodies: We all [email protected] it from biology lessons at school: Laura HayesAntibodies help us to ward off disease Ravinder Dhindsaand are essential components of our Jennifer Jamesimmune system. What many people donot know is that physicians and scientists Contributing Writersuse animal antibodies to identify dis- Dr. Fahad Basheereased or mutated cells. This makes them Dimitre Assenovan important instrument in the diagnosis Markus Köllerof diseases such as cancer. ImagesEnjoy the reading! commons.wikimeadia.org morguefile.com 2 pixabay.com www.ispectrummagazine.com [email protected] +44 7517 864 167 (UK) Follow Us

The Chemistry of Stress:How It Affects Our Health?byDr. Fahad BasheerAuthor of “The Science of Emotions”D o you know why and how exact- During my general practice, I often ly our negative thoughts impact encounter many cases that stem from badly on our body? stress. Gastritis; yes of course is one of the common clinical presentations that come in O.P. A thorough evalu- ation of the patient’s day will clear- ly explain why exactly he developed gastritis. Most of them would admit that they had a stressful day. 3

Here is an interesting study con- Do you know what exactly hap-ducted on prisoners of the World pens in our body when we undergoWar II, and it was found that stress?the risk of developing peptic ulceramong them was twice higher than Imagine that you have met withthat of the controls. There are sev- an accident. What happens next?eral other cases like stress induced The adrenal gland which is locatedhypertension, diabetes, bronchial just above the kidneys, responds toasthma, infections etc. that comes the accident by releasing an emer-to an O.P. This might make one gency hormone known as adrena-think why stress can cause several line into the bloodstream. This hor-clinical disorders. We shall know mone helps in combating daily lifewhy this happens in the last part of stress by changing the body physi-this article. ology. The adrenaline decreases the flow of blood to the gut and shuntIn our daily life we often undergo the blood to the body musclesstressful situations. There is no to tackle the tough situation theavoiding them. The stress thatone experiences is nothing but theresponse of the body to outer envi-ronment and the mind to our innerfears. These inner fears may be onaccount of anything like an exami-nation, a job or responsibility, thefamily, an encounter with a personor situation one dislikes or fears,etc. (1) 4

Photo credit :By Jvnkfood (Own work) [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons body is faced with. This gives you more ener- gy in muscles to com- bat the accident. The adrenaline produced at that time shuts down the functioning of the immune system and gut by decreasing its blood supply. This is known as the flight or fight response. This natural response is one of the greatest gifts to human body in com- bating external threats that we often encoun- ter in our daily life. This response gives us more power and energy to survive any external threats like accidents, being chased by wild animals etc. (1) This was the case in ancient ancestors. One flight fight response would save their life from wild animals. This flight fight response is present in every ani- 5

nal threat, “the stress” is managed. Here in “stress” the hormone causes more harm than good. (1) Do you know why and how exactly our nega- tive thoughts impact badly on our body?mal to combat their Normally when an exter- The latest researchenemies and to save nal threat (accidents, reveals that this adren-their life from its exams etc.) is removed, aline is not only pro-predators. Once the adrenaline production duced while combat-external threat van- gets stopped and the ing an accident, threatishes, the flight fight body will restore its or disaster, but alsoresponse subsides and normal functioning. produced when a manbody restores its nor- But in stress, where undergoes stress. Themal functioning. (1) the threat is internal stress is indeed a dis- (negative thoughts and ease of a modern man.But the question arises negative emotions) The stress follows himwhy modern man faces will constantly stimu- where ever he goes.this much stress unlike late the production of The research showsthe animals? adrenaline. This will that “the adrenaline is cause deleterious and even produced in the harmful effects in our body when a person body unless the inter- undergoes a negative thought in his mind, 6 or even when he feels negative emotions”

and “the adrenaline is producedthe same moment he experiencesnegative thoughts and negativeemotion”. The fact is that “there isno time lag between production ofadrenaline and negative thoughtsthat pass through his mind or thenegative emotions he feels within”.(1)So how badly will this Adrenalineaffect our body? Adrenaline causesthe following: 1Increases bloodsugar:Adrenaline increaseglucose productionfrom liver to blood anddecreases the productionof insulin thereby increas-ing the blood sugar. Thispredisposes to diabetes mel-litus. (1) 7

2Increases bloodpressure:Adrenaline increasesblood pressure by con-stricting arterioles andveins thereby increasesthe blood pressure. Thispredisposes to hyperten-sion. (1) 3 Increases risk of cardiac diseases: Adrenaline increases the rate, force and contraction of heart muscles and causes arrhythmias. Concurrent stimulation of heart due to stress can put heart on increased work- load leading to increased chances of getting a heart attack. Women have a premenopausal estrogen that protects them from stress related heart disease. (1) 7

4Increase Obesity:Adrenaline can move fatfrom storage depots andrelocate it to fat cell depos-its in the abdomen. Thiscauses an increase in bodymass index and generatesobesity. The obesity is oneof the risk factors for devel-oping diabetes and cor-onary artery disease. Insome cases, patient loseshis weight. (1) 5 Indigestion and chronic constipation: Adrenaline decreases blood supply to gut and decreases peristalsis of bowel and increases sphincter tone by acting on its receptors. This leads to indigestion and chronic constipation. (1) 9

6Increases susceptibilityto bacterial, fungal andviral infections:Adrenaline suppresses the func-tioning of immune cells requiredto combat infectious diseases andthere by increases the suscepti-bility to bacterial, fungal and viralinfections. Stress increase suscep-tibility for H.pylori infections instomach to the common gastri-tis. Chronic stress can increasechance for Urinary tract infectionsin females. (1,2)7Increases muscle ten-sion:Adrenaline increases blood flow to shoulder pain, backache and bodymuscles and cause increased mus- pain. Chronic stress induced mus-cle tension to cause tension head- cle tension can later predisposes toaches that we often experience at fibromyalgia etc. (2)the end of our working days. Thetight muscles can cause, headache, 10

89Decreases interest in Alters Menstrual cycle:sex: Chronic stress can cause irregularAdrenaline decreases the testoster- or no menstruation. Sometimes itone produced in men and estrogen can cause heavy or painful bleed-in women that is needed for sexual ing. (2)arousal. Chronic stress can causedecreased sperm production and 10erectile dysfunction or impotence.(2) Creates psychic disor- ders: Chronic stress is one of the funda- mental causes for conditions like over eating, less eating, alcohol and drug abuse. (1,2) So what exactly is the solution for attaining health? The answer is simple but tough to achieve. Wipe away our daily life stress!11

So how do we wipe away REFERENCES:our stress? (1) The Science of Emotions: Dr. FahadIt’s by bringing our uncontrolled Basheerthoughts and emotions into our (2) The effect of stress on the body: Anncontrol. PietrangeloSo how will we bring ourthoughts and emotions tocontrol?NLP psychotherapeutics, mindful-ness and meditation are such won-derful tools in achieving masteryover our thoughts and emotions.12

I, the Alien by Dimitre AssenovM Flora is natural to this with its natural “skin” this species planet needing only the gets sunburned easily and can die sustenance the planet within minutes in cold environ- and sun provides. ments. So, to adapt, it has done what no other species needsFauna appears to cope very well to do – it has created artificialwith the planet’s environment environments on this planet toand has evolved and adapted to survive – a fundamental require-the planets changes with time. ment of this is the destructionThere is only one species that of the planet’s natural flora andappears out of place, for instance, fauna. 13

These species are not native tothis planet but have been intro-duced to it and are therefore thealiens they are searching for. Thesespecies are looking at this wholescenario incorrectly and ironicallycreated convenient artificial des-information division named “reli-gion” to keep the masses intact.By its nature these species are destructive yet ironically amazingly loving and doThey are still at the primitive not have the capability tech level of making life an to yet find who or what actually placed them on absolute utopia. the planet because their philosophers and scien- tists think each other are wrong when both are correct. There are a great number of phe- nomena on the planet that only can be explained after implicating the unusual algorithm of superior tech- nology, which comes from outside the world we know. This makes it extremely difficult to provide grounded answer of the common question “why”. This article will revile superior abil- ity of the human body and inten- tionally provide no answer of the purpose.14

Considering the known and completely out- only approximately 5%nature of extreme high side the energy grid, of all humans use thisfrequencies at extreme or remotely searching controlling ability.low energies, this phe- and locating hidden This may sound extremenomena points to unrec- sources of frequency, and unbelievable, butognized application of objects, substances, after you read this arti-dark matter radiation information and even cle you may start think-and its interaction with remotely overtaking or ing another way.human cerebral sub- controlling the mentalconscious ability for state of another. To begin I will pro-information processing. vide a little informationThis includes receiving There is a little about dark matter radi-and emitting messages unknown catch, that ation. This is the radiofrom great distances 15

frequency emitted by normal rotation move- has the ability to acceptany matter and it pen- ment, but it continues additional informationetrates throughout any their vibration at a low that is attached in thespace, object or shield- pace. “Modern” nucle- background.ing, carrying the energy ar science already hassignature of a chemi- some of the knowledge And here is the phe-cal composition. This in this field, but still nomenon I mentionedradio frequency is only cannot find a credible at the beginning. Theaffected by deep cryo- explanation for a lot human body is angenic cooling; when the of observed anomalies. extremely complicat-atom particle deceler- This radiation is carried ed bio kinetic machineates or suspends its by so-called X-field and 16

and has the ability to rapidly auto- From a purely technical point, theadjust and correct, unfortunately in same blood distribution piping com-a very narrow energy band. prises a complicated 62,000 mile long liquid antenna that has phe-This bio kinetic machine has a phe- nomenal application.nomenal hydraulic piping systemwith a total length of 62,000 miles. We need to point out that such longThe medical field consider the blood antenna cannot be practically builtdistribution system a major surviv- because that will be burned offal component, providing continu- from the generated heat along theously vital nutrients and oxygen to length. Purposely this was done inany cell in the body, and it takes all the human body. First I will clarifyreleased toxins and carbon dioxide why we have to consider the bloodaway for disposal. system as a 62,000 mile long liquid wire. Let’s take a look at the cross section of the arteries and the veins17

– multi-layer tubing, each havingdifferent electrostatic properties.And here is the surprise in that ithas a similarity with other well-known wires with a similar cross-section – the coaxial cable. The minor difference is that the coaxial cable has at the center a single solid wire (this error was corrected in the new coaxial cable type), and in the arteries and veins we have liquid in the form of a con- stant chemical composition, tem- perature and velocity. In order to completely recognize the similarity, here is the cross-section of the new low-resistance coaxial cable. 18

The purpose of this lit- long as possible for it side interference. Thistle difference will be to be able to detect is exactly the same inexplained later, but the as weak a signal as humans where all prob-major liquid application possible (reference to lems were resolvedis that this system also Hertz’s detector, where simply, but extremelyworks as a universal the sensitivity can effectively. When theparticle decelerator cir- reach levels of 0.001 wire is too long it gen-cuit. microvolt’s). To com- erates heat that can plicate the picture, the burn the wire off. ThisThe technical similari- purpose of the coaxial issue in the humanties can be summa- cable is also to pre- body is prevented withrized as follows: in the vent via shielding, as the temperature con-long wire antenna, the much as possible, the trol and double attenu-purpose is to be as loss of signal from out- ation. 19

This triggers a chemi- In order to complicate = I / 2f.c). Here is thecal temperature con- the picture, let us get technical description.trol within a three- back to the first dia- The blood comprisessecond time segment. gram which indicates water, which oscillateProblem solved. The that half of the sys- at a frequency of 3657second is called atten- tem has a high con- cm -1 wavelength. CO2uation – this is neg- centration of CO2 and oscillates frequency ofative noise frequency the other half has a 1334 cm -1. Oxygenbuildup that at some high concentration of oscillates at a frequen-point will overwrite the oxygen. Considering cy in the range of 1103signal. Technically this the chemical difference cm -1 wave length.is resolved via attenu- each half oscillates Either component hasation or signal ampli- in a slightly different a harmonic frequencyfiers. In the human harmonic frequency, lower than water whichbody this was resolved which when combined, means that each com-in the simplest but makes a perfect fre- ponent deviates frommost effective way – quency oscillation filter the base water fre-with polarity switching, bridge (ref. to following quency at a slightly lowknown as attenuation. equations Vpp = I / R amplitude.In the human body this where R = 2f.c > Vppattenuation was donetwice – once in the lowertorso and the secondtime in the neck. Thisprevents overheatingof the body from oneside and it protects thebrain from the otherside. 20

This provides the human body with no one until now has made a cur-the ability to automatically control rent determination in Giga Hertzthe current in a way so as to not frequency band where the RV radioallow overheating (unfortunately frequency is located). dssdssThe 62,000 miles of wire gener-ate a signal from the surroundingenergy field continuously – the fol-lowing diagram was developed formedical purposes for a MRI or CADScan. 21

The exact same system is interact-ing with a geomagnetic field all thetime we are awake – it is just thatno one pays attention, because dur-ing human mutation this sensationwas suppressed. But this functionwill still continue at a subconsciouscerebral level.This means that our body detects object. One more thing to keep inradio frequency signals from the mind is that the dark matter radia-surrounding space all the time. tion cannot be shielded – it pene-The problem is that, for whatever trates everything and everywhere.reason, our brain cerebral interface Human scientists continue to argueloses the ability to inform us. The about what the X-field actually is.detection stays completely sepa-rate in the background of our con- One of the simple principles for arti-sciousness and only few that are ficial sensation of electric current inwired differently continue to have a coil is the model of the electrica practical sensation. meter each home is equipped with. Any time we plug an appliance intoSurprisingly with little help fromoutside, this sensation can berestored to everybody. And witha little training this sensation canbe upgraded to a level of signalemitting or remote signal intercep-tion. Here I will recall the physicsfundamental, that any matter is asimple ration between the energyof the field to the energy of the 22

the circuit, the coil starts transmit- zero when the wires become paral-ting electrons, which start rotating lel to the coil. This is exactly thethe wheel of the meter (the rotation reason that the dozing wires rotateis equal to the sinus of Amperage only at 90 degrees.– this means more amperage isequal to a fast rotation). Because There are several items that need tothe human species has a very nar- be mentioned. First, dozing works,row range of skin resistance (from not only, with water or metal as50 to 75 Ohms / cm), constructing some believed, but with any formsuch a measuring wheel requires and type of mater (solid, gas orvery high precision level, perfect liquid requires recognition files forlevitation alignment toward the coil separation).and very low friction along the axel.Another simple and practical Creation of the recognition file isapproach is to use the Dozing a simple 10-second exercise. Eachwires method. Dozing was known created recognition file remainsfor centuries, and very little was stored in the cerebral subconsciousdone to explain how dozing actu- for 72 hours – this correspondsally worked. to the other phenomena of so called magnetic memory of waterModern science considers dozing to (refer to the discovery of pro-be “witch craft” that is practiced by fessor Dr. Masaru Emoto - whohoaxers. Paying particular atten- published a phenomenal book – “tion to dozing and upgrading the Messages from Water” (New Yorksystem (by isolating the wires from Times Bestseller). He discoveredthe hand surface) provides the that water can memorize all energygrounded explanation, that dozing signatures when exposed to chemi-is a simple logo periodic antenna cal compositions, radiation, music,configured in ration 1:3, where the photo images and etc. The bookhigher signal zone is along the wire contained hundreds of photos ofedges at position of 90 degrees rapidly frozen water where crystaltoward the coil and a signal level of23

alignment indicated the relation of the elbow for every human).memorized energy information tothe crystal configuration). Once the three parameters are fulfilled, every human can startFinally dozing is a simple detection immediately practicing dozing.of a rotation/vibration (R/V) radio From another point the dozingfrequency emitted by any matter. wires working exactly as Hertz’sProof of that is when the material detector, via rotating toward theis cryogenically cooled with liquid body coil. Proof of generating elec-nitrogen resulting in the wire rota- tric signal in the dozing wires istion stopping because the R/V radio evidenced by connecting a voltfrequency dropped to a long wave meter to each one (at the timelength (the rotation RF stops and of rotation the small pulse of thethe vibration RF drops to long wave measuring instrument is observed)length). Once the detected materi- because the time of this pulse isal is heated back above rotation RF limited to 3 seconds, therefore athreshold the signal re-appeared complete range measurement can-and the wires started to rotate not be achieved (except if ampli-again. The last one is to dissipate fiers are used to extend the time).the belief that only selected peoplecan practice dozing. Actually the The following diagrams indicatesecret is in wire length and cross- the principle of interaction betweensection that need to correspond to that which is generated by the bodyseveral individual parameters of antenna signal and the rotation ofevery human – it is ratio of body dozing wires as direct indication ofhigh (there is a specific point of signal location, direction or evenmeasurement), heart pulse rate distance to the source.and skin resistance (one forgottenuniversal constant representing thelength ration between human bodyelements – for example – the palmlength is in ratio to the length of 24

The detection ability is ings, stolen items, fly- or other organic ill-unlimited and relates ing objects (planes or nesses (you can dis-to personal preference. drones at distance over tinct, remotely, whichDetection includes 3000 feet) etc. one from two identicaleverything and is not bottles of water is filledlimited to radioac- The detection works by with hot one).tive materials, metals, moving vectors with aliquids, medical sub- speed of 40 MPH with The mentioned 5%stances (including nar- a precision of 3 ft or of the human speciescotics), cell phones less (including cars or who are wired differ-or other transmitters, helicopters). Because ently (commonly afterburied objects, live or the detection precision near dead experience)abandoned utility lines, is phenomenally high it extend this phenome-explosives and ammu- can also be applied as non to remote viewingnitions, buried corpses, a non-invasive detec- information intercep-or people in avalanch- tion of cancers, tumors tion, where the medi-es or collapsed build- 25

tation is simply the cre- species was subject to These unnoticed indi-ation of a recognition specific genetic muta- viduals are working infile. The remote trans- tions that makes the the background, silent-mission or detection of subconscious ability ly, and are already rec-brain signals between more dormant. Only ognized as a greaterindividuals is working selected ones who are threat to the globalbut has no explanation. subjected to traumat- elite, by simple vir-Where the future of ic rewiring events can tue that they are outthis phenomena stays. keep this phenomenon of the boundaries ofThe technology already alive. These human mind control. The posi-provides access to species were already tive is that the eliteimplantable devices marked with the sign still cannot figure outthat can successful- of asymmetrical muta- how physically identifyly replace the dozing. tion, and are general them. But they know,From another site the engines of phenomenal only to well, how thissophistication and sim- technological progress. will end.plicity of the phenom-ena can be exploredfrom some in incor-rect ways for gainingremotely hidden orrestricted informationor gaining control overthe individual.Exposing of this phe-nomena involves, oneway or other, the greatmoment of actual physi-cal “contact” the humanspecies dreamed of. Forgenerations the human 26

Why Emotions Influenceour Immune SystemHealing Autoimmune Disorders with NLP by Dr. Fahad Basheer Author of “The Science of Emotions”A utoimmune Disorders! ders is unknown. Therefore, mod- Autoimmune disorders are a ern medicine writes its cause as idiopathic. Most of the pathology group of disorders in which of diseases in our body is medi- ated by immune cells. But what our immune cells destroy do we know about how our emo- tions control our immune cells thatour own cells. Thyroid disorders, decides the nature of autoimmune disorders.diabetes, systemic lupus erythe-matosis etc. are a few examples ofautoimmune disorders. Still today,the etiology of autoimmune disor- 27

In her research, Dr. Candace Pert Dr. Candace Pertdiscovered that cells in our body (1946 – 2013)communicate with each other inthe form of neuropeptides. These Neuropeptide synthesisneuropeptides act as a vehicle thatcarries information from one cellanother. These neuropeptides causeaction in a cell by binding to thereceptors present over the cells. Bydoing so, these neuropeptides con-vey information to the cell’s DNAand cause an amazing reactionin cells. The process of binding ofneuropeptides over cell receptorsis known as “sex on a molecularlevel”.But the turning point of the researchwas when Dr. Candace Pert discov-ered that 85 -95% of neuropep-tides are found in the limbic systemincluding amygdala, hippocampusand the limbic cortex. These areknown as the storehouse of emo-tions in the brain. In 1920, research-ers were successful in stimulatingthe limbic cortex over amygda-la. Pert found high concentrationsof neuropeptides in these loca- 28

Photo credit: Blausen.com staff. “Blausen gallery 2014”. Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. - Own work tions (limbic system) Later, she discovered with the limbic system where the information that the receptors for of our brain through from our five senses is these neuropeptides neuropeptides. In other relayed. This brought a were also found on the words, the program of new light of discovery immune cells. For every emotions was conveyed that the limbic system neuropeptide that was to the immune cells. had an amazing con- found in the brain, The nature of emo- nection with the neu- the immune cell had tions exactly exhib- ropeptides that carries the exact receptor for ited the behaviour of information. The limbic these neuropeptides to immune cells. If the system in other words bind. This was the most emotions were destruc- conveyed the infor- groundbreaking discov- tive, immune cells also mation of emotions to ery of them all,because exhibited destructive these neuropeptides. it has proved that our behaviour causing the immune system con- destruction of the body’s stantly communicates own cells. 29

I call this phenomenon In other words, cells der.of transferring emo- in our body share thetions from the limbic information of our emo- The find-system to the body “the tions. Each organ in our ings fromparadigm shift of emo- body is virtually a bat- my psy-tions”, because I later tery of emotions too. chother-experimentally proved The negative emotions apeuticthis discovery by the being harboured in the experienceapplication of NLP psy- respective site was the were that:chotherapeutics over other possibility of the The self-my clients with autoim- site of development of destructivemune disorders. I repro- pathology or the disor- emotionsgrammed their emo- like self-tions with the world’s criticism,best known psycho- guilt andtherapeutic tools of the revenge21st century. This gave were theme the most amazing most top-and marvellous results ratedby a total resolution of negativethe autoimmune disor- emotionsders in some of my which created the self-clients, whilst some of destructive programs inthem had a marked the immune cells caus-decrease in the clinical ing the immune cells topresentations of symp- attack their own bodytoms and signs of auto- cells. When we wereimmune disorder. The successful in repro-emotions transferred gramming the negativefrom the limbic sys- emotions with the posi-tem encoded later in tive emotions with thethe cells of our body NLP psychotherapeu-known as Bio-memory. 30

tics, we discovered that there wasa total resolution of autoimmunedisorders. On the other hand, thosewho didn’t totally resolve from theautoimmune disorder had a mar-ginal decrease in the symptomsand signs of an autoimmune dis-order. It was found that positiveemotions like love, care, affection,forgiveness and letting go, thatapplied in the psychotherapeutics,were highly powerful to completelyheal and resolve autoimmune dis-orders of the clients.Yes! By programming our emo- the immune cells. The transferredtions we are able to program the information of emotions programsfunctioning of the immune cells the DNA to transcript and trans-in our body because the behav- late to produce its protein. In sum,iour of immune cells is nothing but each emotion will lead to the syn-the behaviour of human emotions. thesis of a particular type of proteinIn short, “Each neuropeptide is in the body”. And the “nature ofnothing but a vehicle that carries emotions determines the nature ofinformation on emotions stored in message carried by the neuropep-the brain. So, whenever the brain tides and the information in thesereleases these neuropeptides an neuropeptides will determine theemotion will be embedded in them in behaviour of the immune cells ofthe form of information. Whenever our body”. “Self-destructive emo-these neuropeptides bind to a cellreceptor, this embedded emotionwill be transferred to the DNA of 31

tions will force the immune sys- REFERENCES:tem of our body to attack its ownbody cells creating autoimmune 1) The Science of Emotions: Dr. Fahaddisorders, whereas self-construc- Basheertive emotions are able to bringabout resolution and healing of theautoimmune disorders. Thus, byprogramming the emotions usingNLP psychotherapeutics, we areable to heal the autoimmune disor-ders that modern medicine is fight-ing hard to cure with steroids andimmunomodulators”. 32

Immunohistology:Antibodies show usdiseased cells by Markus KöllerWe all know it from biology lessons physicians and scientists use animalat school: Antibodies help us to ward antibodies to identify diseased oroff disease and are essential compo- mutated cells. This makes them annents of our immune system. What important instrument in the diagno-many people do not know is that sis of diseases such as cancer. 33

The key to immunohistology: The bindingfeatureA ntibodies are formed in cer- tain blood cells in response to substances that the immune system classifies as harmful.These so-called antigens are mol-ecules that are located, for exam-ple, on the surface of viruses orbacteria. Again, the antibodies bindcertain areas of the antigens calledepitopes. This way, they signal theimmune system to reduce theseforeign binding structures.This binding character is also use-ful in diagnostics: In the immuno-histology or immunohistochemistryprocedures there are antibodiesinserted to make certain structures,such as proteins, visible. “Theseprocedures have been used sincethe late 70’s and have been con-tinuously improved and expanded,”explains Jürgen Frerichs, head ofDIANOVA GmbH (www.dianova.com),one of the established commercialenterprises in the sector. 34

Targeted synthesizingof antibodiesTo put it simply, bio- injecting one specific tion stimulates thetech companies and antigen into a mouse, body to create a greatresearch institutions a goat or a horse. The amount of antibodiesproduce antibodies by ensuing immune reac- with several bindingSecondary antibodies binding primary antibodies. The result is visible under a microscope. 35

features for the anti- with enzymes that pro- added bridge that con-gen. It is then possible duce visible colorants sists of another anti-to isolate the antibodies or are marked with body (secondary anti-directly from the blood, fluorescing colorants. body) that binds theor even isolate partic- There are two meth- first one (primary anti-ular antibody-produc- ods: The direct and the body).ing blood cells from indirect technique. Thethe mixture extracted latter works with anfrom certain animals,and initiate a complexbiotechnological proce-dure for the productionof an excess of a single Antibodies help to distin-antibody. Antibodies guish tumor cells from eachthat are produced like otherthis are called “mono-clonal”—they emanatefrom one single cell line One example is the anti- mas, which accountand bind just one par- IDH1 R132H monoclo- for about 20 percentticular epitope. nal antibody clone H09 of all brain tumors. of DIANOVA GmbH, by Differentiating gliomas which different brain from other brain tumorsAntibodies are very tumors can be dis- enables us to launchsmall and, even under tinguished from each a targeted treatmenta microscope, not read- other. Originally devel- and helps predict theily visible, which is why oped by the renowned course of the disease.they are specially pre- German Cancerpared for the diagnos- Research Center, thetics. They are coupled antibody labels glio- 36

Multiple advantagesin contrast to genesequencingThe use of antibod- percentage of tumor bodies is that patholo-ies in diagnostics pro- cells in the tissue sam- gists have the resultvides many advantag- ple is a critical factor. right in front of theires in comparison to Immunohistochemistry eyes—they can differ-molecular-biological is faster and cheaper entiate diseased frommethods, especially in than gene sequencing healthy cells underthe diagnosis of brain procedures. the microscope,” saidtumors, when there is “Another advantage of Frerichs.often less tissue avail- the immunohistochem-able. In addition, the ical method with anti-Jürgen Frerichs, head of DIANOVA GmbH (www.dianova.com), one of the established commercial enterprises in the sector. © www.jan-altenschmidt.de 37

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