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CDMX WEDNESDAY, OCTOBER 4 MEXICO 8:00 - 18:00 Pre-meeting course “Fundamentals of Glycobiology”CONGRESSPALACE OF THE SCHOOL8:30-9:30Principles of Glycobiology OF MEDICINE Iván Martínez Duncker 9:30-11:00 N-glycosylationO4CTO-B7ER 11:00-12:00 Tania VillanuevaLATIN AthMERICAN 12:00-12:30 O-glycosylation OF GLYCOBIOLOGY 12:30-14:00 Kathya Gutiérrez Coffee Break 14:00-15:00 15:00-16:00 Congenital Disorders of Glycosylation Iván Martínez Duncker 16:00-17:00 Lunch 17:00-18:00 Glycobiology and Cancer Verónica Vallejo Ruíz 14:00-18:00 Glycobiology and Metabolic Disease 19:00-21:00 Yobana Pérez Structural analysis of glycans Gleysin Cabrera Registry Cocktail reception

THURSDAY, OCTOBER 508:30-09:00 Inauguration 11:00-11:20 Gustavo Niño Vega - Universidad de Guanajuato, Iván Martínez Duncker Mexico President of the Latin American Society for 11:20-11:50 Molecular mechanisms of fungal cell wall assembly and remodeling, as potential targets for the design of Glycobiology 11:50-12:20 antifungal strategies Keynote: Leila Lopes Bezerra - Universidad do Estado Head of the Glycoscience in Health Thematic 12:20-12:40 do Rio de Janeiro, Brazil 12:40-14:00 The human endothelial cell proteome is modulated by Network a cell wall polysaccharide of an opportunistic fungal pathogenPRESIDIUM Keynote: Luis Carlos Castillo Barahona - Universidad1. Dr. Germán Fajardo Dolci, Director de la Facultad de Medicina UNAM La Serena, Chile2. Dr. Arturo Edgar Zenteno Galindo, Comité Organizador N and O-Glycosylation are involved in cell wall3. Dra. Verónica Bunge Vivier, Directora de Redes e Infraestructura organization, adhesion and virulence in theCientífica-Conacyt ubiquitous plant pathogen Botrytis cinerea4. Lic. Pablo Zazueta Carpinteyro/Lic. Alma Delia Pérez Villanueva, Poster “Lightning talks”Programa de Redes-Conacyt Lunch5. Dr. Octavio Tonatiuh Ramirez Reivich, Director del Instituto deBiotecnología UNAM09:00-10:00 OPENING CONFERENCE Session 2: Microbial and pathogen glycobiology10:00-10:30 Robert Sackstein Chair - Héctor Mora Professor, Harvard Medical School, USA Director, Program of Excellence in Glycosciences 14:00-14:30 Keynote: Gerardo Vasta - University of Maryland, USA Coffee Break 14:30-14:50 Role(s) of galectin-glycan interactions in microbial andSession 1: Glycobiology of pathogensChair - Everardo López parasitic infection Juana Elizabeth Reyes Martínez - Universidad de10:30-11:00 Keynote: Héctor Manuel Mora Montes - Universidad Guanajuato, Mexico de Guanajuato, Mexico Biocatalysis for the synthesis of complex carbohydrates Bringing glycobiology and immunology together, a fungal perspective

FRIDAY, OCTOBER 614:50-15:20 Coffee Break Session 2: Glycobiotechnology15:20-16:00 Keynote: Sabine Flitsch - University of Manchester, UK Chair - Sabine Flitsch16:00-16:20 Tools for structure-function studies of glycoconjugates Igor C. Almeida - University of Texas at El Paso, USA 09:00-09:20 Gleysin Cabrera Herrera - Centro de16:20-17:00 Synthetic glycan- and peptide-based vaccines protect Ingeniería Genética y Biotecnología, Cuba17:00-19:00 against heart inflammation and parasite burden in a 09:20-09:40 Treatment with Heberprovac changes of nonhuman primate model of Chagas disease 09:40-10:00 Selected oral presentations O-glycans profile in prostate cancer patients Poster Session 1 10:00-10:20 Asapanalitica 10:20-11:00 11:00-13:00 Laura Alicia Palomares Aguilera - 13:00-14:00 Instituto de Biotecnología, UNAM 14:00-15:00 Redox potential and the N-glycosylation profile 16:00------- of monoclonal antibodies Octavio Tonatiuh Ramirez Reivich - Instituto de Biotecnología, UNAM Influence of bioprocessing conditions on the glycosilation profile of recombinant proteins Selected oral presentations Poster Session 2 Thematic Network: Challenges and Opportunities Lunch Tour at Historical Center of CDMX

SATURDAY, OCTOBER 7Session 3 Metabolic and degenerative disease 14:20-14:50 Keynote: Bo Rueda - Massachusetts General Hospital, USAChair - Edgar Zenteno Targeting the Sialyl-Thomsen-nouveau (STn) antigen to develop treatment strategies for high grade ovarian cancer9:00-9:30 Keynote: Dulce Papy-García - Universite 14:50-15:10 Verónica Vallejo Ruiz - Centro de Investigación Biomédica Heparan sulfate in the Alzheimer brain. Are these9:30-9:50 glycans involved in the development of the 15;10-15:30 de Oriente, Mexico9:50-10:20 pathology? 15:30-15:50 Marie-Ange Krzewinski Reichhi - Université de Lille, France 15:50-16:10 Human papillomavirus oncoproteins modulate glycogene10:20-10:40 State of the art of CDG in Europe… and in Lille (France) Keynote: Hudson Freeze - Sanford Burnham Prebys 16:10-16:30 expression profiles10:40-11:10 Medical Discovery Institute, USA Congenital Disorders of Glycosylation: Progress and 16:30-16:50 Coffee Break11:10-11:30 perspectives 16:50-17:1011:30-12:00 Vanessa Dehennaut Lefebvre - Institut de Biologie de Lille, Myron R. Szewczuk - Queen’s University, Canadá12:00-14:00 France 17:10-18:00 O-GlcNAcylation: a new link between nutrition, epigenetics Sialylation facilitates 3D multicellular tumor spheroid and colorectal cancer? Keynote: Tony Lefebvre - Universite de Lille 1-Sciences et formation and cancer initiation Technologies, France OGT: an enzyme standing out from usual Keynote: Ken Kitajima, Nagoya University, Japan glycosyltransferases Coffee Break Differential fate of medaka fish, Oryzias latipes, with Keynote: Chihiro Sato - Nagoya University, Japan Mechanisms that SNPs of the ST8SIA2/STX gene lead different point-mutations in the CMP-sialic acid synthetase to psychiatric disorders Lunch gene Ismael Secundino Velázquez - Instituto de Biotecnología, UNAM, Mexico Erythrocyte sialoglycoproteins bind Siglec-9 to maintain neutrophil quiescence in the bloodstream Tania María Villanueva Cabello - Universidad Autónoma del Estado de Morelos, Mexico x Novel sialoglycoconjugates in T CD4+ cells Sophie Groux-Degroote - Université de Lille, France Molecular mechanism of TNF-induced sialyl-Lewis expression in human bronchial mucosa and effect on bacterial adhesion Closing SessionSession 4 Sialic acid in cancer and immunology Rafael Rubio García, University of Virginia, USAChair - Patricia Gorocica The role of endothelial luminal glycosylated structures and their recognition by lectins in endothelial functions14:00-14:20 Annick Pierce - Université des Sciences et des Technologies 20:00 DINNER de Lille, France Crosstalk between posttranslational modifications regulates delta-lactoferrin antitumoral activities