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4. marinebiotech.org In these pages you will find infor- mation on all aspects of the field including leading research- ers and programs, the tools involved, and relevant upcoming events. Our goal is to present this material in an exciting, ac- cessible information for everyone from students looking for career possibilities and advice to professionals in the field. Appendix VI: Dr. Swati KCR & Dr. Jyotsna Girola: 1. http://www.himalayanclub.org/journal/medicinal- plants-of-the-himalaya 2. http://www.nationalgeographic.com 3. http://www.sciencedirect.com/science/article/pii/S037 8874106006726 4. http://dnp.chemnetbase.com/AAA00.entry?parentCH Number=CCW26&exno=CCW26 5. Berberis Aristata: A Review Sharma Komal, *, Bair- wa R anjan , Chauhan Neelam, Shrivastava Birendra , Saini Neeraj Kumar; School of Pharmaceutical Sciences, Jaipur National University, Jaipur, India 234

6. Burkill, 1966 and Dey, 1984 7. Induction of mitochondrial-dependent apoptosis by an essential oil from Tanacetum gracile; Verma M, Singh SK, Bhushan S, Pal HC, Kitchlu S, Koul MK, Thappa RK, Saxena AK; Division of Pharmacology, Indian Institute of Integrative Medicine, Jammu-Tawi, India. Planta Med. 2008 Apr;74(5):515-20. doi: 10.1055/s-2008-1074503. Epub 2008 Apr 10. 8. Medicinal Plants: Chemistry & Properties by M. Dan- iel 9. http://www.deepdyve.com/lp/elsevier/isolation-of-a- powerful-antioxidant-from-olea-europaea-fruit-mill- W4Xmx0CH93 10. http://www.naturalmedicinalherbs.net/herbs/r/rheum- spiciforme.php 11. http://www.academicjournals.org/jmpr/pdf/pdf2012/2 3May/Pant%20%20and%20Rinchen.pdf 12. http://ephedrinediet.org/ephedra-gerardiana/ 235

13. http://www.naturalmedicinalherbs.net/herbs/r/rosa- webbiana.php Science Citation: Surinder Kitchlu 236

Authors INSERIRE COLLAGE DEGLI AUTORI SIMILE A QUESTO 237

Dr. Anna Maria Clement began her career as a natural health advocate in her early adult years, after her family had embraced a plant-based diet. Her interest in learning from the global natural health movement burgeoned into a part time job as she was academically learning about the foundation of anatomy, biochemistry, and health. At the same time, she founded Scandinavia’s very first “Living Foods” organiza- tion. As a member of the Natural Health Care Coalition of Sweden, a government supported effort in unifying the field of complementary healthcare, she was able to help countless people on the path to health. Anna lectures extensively worldwide, including the Kaunas University of Lithuania, Nobel Hall in Stockholm, Sweden, University of Manchester, Exeter University, U.K., and an endless list of others. Dr. Anpurna Kaul works as scientist in Pharmacology Di- vision of Indian Institute of Integrative Medicine (CSIP), Jammu, India. She has completed her Ph.D in 1996 from University of Jammu. Her field of research is immune phar- macology. Dr. Kaul has 35 research publications in national and international journals, 12 patents and also presented sev- eral research papers in various symposia/conferences. She has screened more than 4000 plant extracts/fractions and pure compounds on immune system by in vivo and in vitro methods. She has also actively participated in Indo- Malaysian research project as member and visited Malaysia in 2007 to attend Women’s Health and Asian Traditional Medicine Conference. Dr. Asha Chaubey is presently working as Senior Principal Scientist and Head of Fermentation and Microbial Biotech- nology Division. She has been working in the area of fermen- tation technology for exploration and exploitation of micro- organisms for the production of bioactives and novel en- 238

zymes for more than 18 years. She obtained Ph.D. degree from LLRM Medical college, Meerut in collaboration with National Physical Laboratory in the field of biosensors for diagnostics. During the doctoral research; she has significant- ly contributed towards the development of biosensors for health care and generated good quality publications and patents. Dr. Brian Clement began his journey to embrace a healthier way of life at an early age of 20. For half a century, Clement has expanded his knowledge and competency by stretching the boundaries, borders and limitations of his realm. Clement joined the HHI team at their Boston facility in 1975. Within a year he was representing the institute via lectures, seminars, conferences, and TV and radio interviews. In addition, he was published in much of the print media throughout the US and Europe. With his wife and Co Director Anna Maria Clement, they have worked tirelessly to build the Institute’s outreach, advance technologies, and scope of offerings. This sprawling Institute rests on sixty tropical acres. At the turn of the twenty-first century the Institute received the notable award as the world’s foremost healing center. Dr. Rekha Sapru Dhar specialises in the Molecular charac- terization of the germplasm of aromatic and medicinal plants. Molecular cloning and functional validation of genes in- volved in the biosyhthetic pathways of Withania somnifera; Picrorrhiza kurroa and Pelargonium graveolens. She has 36 publications and 1 patent. Dr. Suphla Gupta’s core research areas includes Plant Mo- lecular Biology, DNA Fingerprinting and Barcoding, Tissue Culture and Plant Proteomics. These are the approaches be- ing utilized in her Lab to understand secondary metabolite 239

biosynthesis of medicinal plants, development of tissue cul- ture protocols for rare and endangered plants and plant bar- coding and fingerprinting for Intellectual property rights pro- tection. Her Lab has also chemically and genetically charac- terized and catalogued more than 250 Ginger germplasm from North western Himalayas and DNA barcoded medicinal plants collected from Cold desert areas of Leh and Ladakh region of India. She has published more than 40 peer re- viewed research papers, delivered eleven invited Lectures and attended over fifty International & National Confer- ences. Dr. Sushma Koul has more than thirty eight years’ experi- ence in development of propagation protocols of high alti- tude medicinal and aromatic plants with their implication for conservation. Production of bioactive metabolites in vitro. Development of bioreactor system for plant cell & or- gan cultures Plant fermentation for production of plant bioac- tive and value additions through biotransformation utilizing plant cell suspension culture system. Adaptive Biology and plant Physiology. She has published 40 papers and has 3 pa- tents. Dr. Vidushi Mahajna completed her B. Tech & M. Tech with distinction from Amity Institute of Biotechnology, Amity University Noida, U.P, India followed by Ph.D in Plant Biotechnology from Council of Scientific and Industri- al Research (CSIR)-Indian Institute of Integrative Medicine (IIIM), Jammu, India Dr. Mahajan has published her research findings in about 23 peer-reviewed International Journals. She has presented her research finds at national as well as in- ternational forums in series of International and National Conferences during her research carrier. 240

INDEX Prologue Food IS Medicine ……………………………….13 Introduction……………………………………………..…21 Chapter 1 Current Perspectives of Fruits as Potent Immuno- modulators…………………………………………………27 Chapter 2 Ex Situ Approaches for Conservation of Himala- yan Medicinal Plant Biodiversity………………………….43 Chapter 3 Phytochemicals as Immunomodulatory agents…75 Chapter 4 Bioactive Potential of Endophytic Microorganisms & Bio prospecting Microorganisms for Drug Discovery and Development……………………………………………..109 Chapter 5 The Super food: Spices………………………..129 Chapter 6 Bioprospecting Marine Plant:Window to the Blue World…………………………………………………….145 Chapter 7 Medicinal plants from Himalayan Region……163 References……………………………………………….181 Authors…………………………………………………..237