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THE ROAD TO POLICY AND CLINICAL INTEGRATION June 24-28,2023 htai2023.org #HTAi2023Adelaide

Thank You to All Our Sponsors and Exhibitiors PLATINUM SPONSORS DIAMOND SPONSORS HEALTH ECONOMICS and GOLD SPONSORS SILVER SPONSORS HEALTH TECHNOLOGY ASSESSMENT

Contents 5 Introduction 6 8 President’s Welcome 9 Local Organizing Committe’s (LOC) Welcome 11 HTAi 2023 Local Organizing Committee (LOC) 12 International Scientific Program Committee’s (ISPC) Welcome 14 HTAi 2022 International Scientific Program Committee (ISPC)  16 About HTAi 17 Interest Groups 18 HTAi Policy Forums HTAi Secretariat 21 33 General Information 35 Schedule-at-a-Glance 49 Program Agenda 65 Feature Sessions 71 Workshops  81 Panels 97 Orals 111 Posters HTAi and Associated Meetings 112 112 HTAi and Associated Meetings 113 HTAi Policy Forum Meetings and Sessions HTAi Interest Group Meetings 115 119 Symposia Sponsors /Exhibitors 120 125 Platinum Sponsors 127 Diamond Sponsors 129 Gold Sponsors 131 Silver Sponsors 135 Exhibitors Principal Funding Partners Data Accuracy Disclaimer: Program information accurate as of June 6, 2023

CRICOS 00123M PRV12105 Critical thinking for critical decisions in health Established in 2001, Adelaide Health Technology Assessment (AHTA) evaluate the safety, effectiveness and value for money of health interventions; inform evidence-based policy and practice using proven methods; innovate, research and develop new health technology assessment (HTA) methods; and build capacity in the HTA workforce. HTA Course hOurHTA The HTA course takes a practical view of Connect with HTA professionals in Australia how health technologies, such as medical and New Zealand and attend hOurHTA: a brand procedures, devices, tests, pharmaceuticals new webinar series for people working, or and public health interventions, should be wanting to work, in HTA. assessed to inform policy decisions regarding access to and funding of these technologies. hOurHTA will host speakers from across the HTA community on cutting edge topics in HTA. The online HTA course runs from July to November each year. The first webinar in this exciting new series will be in July 2023. To find out more contact: [email protected] To register your interest contact: [email protected] Contact us phone +61 8 8313 2030 email [email protected] web health.adelaide.edu.au/adelaide-health-technology-assessment UA30696 4

Introduction

INTRODUCTION President’s Welcome Dear friends and esteemed colleagues, compelling platform for the discussions surrounding the theme of this year’s Annual It is with great pleasure, and on behalf Meeting: The Road to Policy and Clinical of the HTAi Secretariat and the Board Integration. This region is experiencing of Directors, that I welcome you to the growing interest and implementation of HTAi 2023 Annual Meeting in Adelaide, HTA, and its diverse cultural, social, and Australia. As we gather in the beautiful city economic contexts in which HTA takes of Adelaide, I would like to acknowledge place presents unique challenges and the traditional custodians of the Adelaide opportunities. Working collaboratively, Plains, the Kaurna people. We recognise and engaging diverse perspectives, and respect their cultural heritage, beliefs and building connections is essential to enable relationship with the land. We acknowledge the integration of clinical and policy that they are of continuing importance approaches to health technologies. This is to the Kaurna people living today. It is nicely captured in the Thai notion of the important that we pay our respects to their “triangle that moves the mountain”, which Elders past and present and extend that conceptualizes how different stakeholders respect to all Aboriginal and Torres Strait work together to address emergent policy Islander people attending from other areas issues. of Australia. Indeed, engaging new voices and diverse I thank you all for joining us for the first perspectives is paramount to the growth entirely in-person Annual Meeting we have and advancement of HTA globally. I am held since 2019. It is exciting to spend this pleased to see that this conference has time with all of you, and I appreciate all of attracted growing segments of attendees, you making the Annual Meeting a priority. such as students and those new to the In increasingly challenging times, including field of HTA. They bring fresh ideas and countries in armed conflict and global perspectives, and their active participation economic slowdown, health technology in discussions and knowledge-sharing assessment (HTA) has even become more can lead to new insights and innovative important as an essential tool to make approaches. I encourage all attendees, informed decisions about the allocation especially the new ones, to engage in of limited resources. HTAi is a community the discussions, ask questions, and take of multidisciplinary academics, advisors, advantage of this opportunity to learn from health professionals, public and private experts in the field. This Meeting provides organizations, students, patients and citizen a valuable opportunity for networking and members. As members of this professional knowledge-sharing, and I hope it will inspire society, our dedication to better health for you all to be active contributors to the field all people and the future of HTA worldwide of HTA. is crucial. We have an insightful and engaging Gathering in Australia, situated in the program ahead of us, with valuable Asia-Pacific region, provides a unique and learnings and information that will traverse 6

INTRODUCTION the many areas of special interest within and approaches. With this in mind, I HTA. We will also have plenty of opportunity encourage you to share your thoughts for fun, with curated entertainment and and engage with presenters and fellow networking events throughout the Meeting. attendees here and online using the hashtag An event of this scale is a tremendous #HTAi2023Adelaide. task. The coordination took support and dedication from many local and I hope you all enjoy your time with us and international organizations, which we find the program as inspiring as I do, as deeply value and appreciate. we travel the road to policy and clinical integration together. I would like to express my gratitude to the HTAi Staff, the local individuals and Truly yours, organizations and event volunteers for the incredible work they have contributed to Dr. Wija Oortwijn the planning and execution of the Annual Meeting. Its success is owed to their HTAi President commitment and dedication. I would also like to thank the International Scientific Program Committee for their wonderful contributions to the exceptional program. The Committee is led by Co- Chairs Professor Guy Maddern, from the University of Adelaide and The Queen Elizabeth Hospital in Australia, and Professor Wim Goettsch, from Zorginstituut Nederland and Utrecht University in the Netherlands. I must also thank the Local Organizing Committee and its Co-Chairs: Professor Guy Maddern, and Dr. Li Ying (Grace) Huang, from the Division of Health Technology Assessment, Centre for Drug Evaluation in Taiwan. It is so great to be back in the Asia-Pacific region after moving the 2020 Annual Meeting in Beijing to a virtual environment. Finally, I thank all of you for joining us this week in Adelaide. The spirit of the Annual Meeting is sharing knowledge, perspectives, 7

INTRODUCTION Local Organizing Committe’s (LOC) Welcome Co-Chair’s Message evolution, provides an ideal stage for such a meeting to take place. Dear friends and colleagues, Over the past few years, the world has On behalf of the Local Organizing faced considerable challenges—the Committee, we are delighted to welcome global COVID-19 pandemic, strain on you all to the Health Technology our healthcare systems and resources, Assessment international (HTAi) Annual conflict, and growing economic Meeting in Adelaide, Australia. It is an pressures. With these challenges comes opportunity to meet experts from around an opportunity; opportunity to build the world in Australia to share their a framework to ensure equitable and knowledge and experiences in the field of responsive health technology assessment, health technology assessment. and to shape the future of HTA worldwide. Adelaide is a beautiful city, renowned for As we navigate through these challenges its wonderful beaches, incredible wine and opportunities, it is important to regions, and arts festivals. Consistently continue to work together and share ranked as one of the world’s most livable our knowledge and experiences. This cities, we hope you feel at home during conference will provide an excellent your stay and take an opportunity to enjoy opportunity for networking, collaboration, all the city and regions have to offer. and learning as we explore the Road to Policy and Clinical Integration together. We would like to thank all of those involved in the planning and organizing Once again, welcome to Adelaide, and we of the Annual Meeting, including wish you all a productive and enjoyable the International Scientific Program Annual Meeting. Committee, HTAi staff, and local organizations who supported the effort. Sincerely, It truly is a collaborative achievement to host an event of this magnitude. Prof. Guy Maddern The 2023 Annual Meeting in Adelaide Dr. Li Ying (Grace) marks a very welcome return of this Huang event to the Asia-Pacific region; the last Annual Meeting hosted in this region was in 2016. Health technology assessment has evolved significantly in the region since then, as many countries establish new agencies and strengthen existing agencies. The strong spirit of international collaboration and information-sharing in this region, and at the heart of this 8

INTRODUCTION HTAi 2023 Local Organizing Committee (LOC) Co-Chairs Prof. Guy Maddern Dr. Li Ying (Grace) Huang RP Jepson Professor of Surgery, University of Director, Centre for Drug Adelaide, Australia Evaluation, Taiwan Professor Guy Maddern is the RP Jepson Dr. Li Ying (Grace) Huang is a director of Professor of Surgery at the University of the Division of the Health Technology Adelaide, Director of Research at the Basil Assessment, Center for Drug Evaluation, Hetzel Institute for Translational Health Taiwan (CDE/HTA). Before joining CDE/HTA Research at The Queen Elizabeth Hospital in 2008, she worked for around ten years and Director, Surgical Research and as a clinical pharmacist in a leadership role Evaluation (incorporating ASERNIP-S) of the in the department of pharmacy in one of Royal Australasian College of Surgeons. He the major medical centers in Taipei. She was trained at the University of Adelaide and completed her Ph.D. degree in Graduate became a Fellow of the Royal Australasian Institute of Health Policy and Management, College of Surgeons in 1989. His clinical College of Public Health, National interests include the development of Taiwan University and Master’s degree in techniques to manage metastatic hepatic pharmaceutical science from the National disease and hepatic approaches to optimize Taiwan University as well. She has authored resection options. He has also published and co-authored articles published in widely on new surgical techniques and several international journals and also serves their introduction into surgical practice. as a reviewer of manuscripts. Her current He has over 500 publications in scientific research focuses on comparative efficacy journals, has contributed to over a dozen of new drugs, applying mixed treatment surgical texts and attracted $65 million of comparison methods, patient involved research funding. The evaluation of new HTA and therapeutic inertia among adult technologies and in particular surgical DM patients in Taiwan. Dr. Li Ying (Grace) technologies is another area of focus and Huang currently serves on the HTAi Board interest. Under his supervision, ASERNIP-S of Directors. Grace has been a member of has been responsible for assessing these the INAHTA Board for the following terms: technologies before exposing the Australian population to them and has provided this Director 2016-2018 and 2019- 2021. service to the Australian and International community for the past 20 years, and is recognized, nationally and internationally, as the premier surgical innovation assessment group. He is a past President of HTAi and a past Chair of INAHTA. 9

INTRODUCTION Members • Dr. Greg Cook, Director of Access, Policy & Advocacy, Australia • Assoc. Prof. Wendy Babidge, General Manager, Research Audits and • Dr. Franz Pichler, Principal & Founder, Academic Surgery RAAS, Australia Confluence Health Consulting Pvt Ltd, Australia • Mr. Andrew Bruce, Head of International HTA and Payment Policy, • Ms. Rebecca Trowman, Scientific Amgen, Australia Secretary, Global Policy Forum, Australia • Prof. Brendon Kearney, Consultant, • Prof. Kwun Fong, Deputy Chair Royal Adelaide Hospital, Australia / Thoracic Physician & Professor, Medical Services Advisory Committee / • Prof. Tracy Merlin, Professor / Director, University of Queensland, Australia AHTA | Interim Head, School of Public Health, Adelaide Health Technology Assessment (AHTA), University of Adelaide, Australia • Mrs. Ann Single, Coordinator / Chair, Patient Voice Initiative / HTAi Patient and Citizen Involvement Interest Group, Australia 10

INTRODUCTION International Scientific Program Committee’s (ISPC) Welcome Co-Chairs’ Message throughout the world, enabling efficient processes to accelerate access to cost- Dear friends and colleagues, effective technologies is more pertinent than ever. On behalf of the International Scientific Program Committee, we welcome you Exploration of this topic will be supported by all to the Health Technology Assessment three sub-themes, explored through Plenary international (HTAi) 2023 Annual Meeting. We presentations: are thrilled to see you all for HTAi’s first entirely in-person meeting since 2019! • Plenary One: Fast-Tracking Clinical Innovation: The Balance of Speed and Over the next three days, we will examine an Rigour array of perspectives and considerations in health technology assessment as we explore • Plenary Two: Making HTA More Efficient: The Road to Policy and Clinical Integration. What Can We Learn about Harmonization, This path is filled with diverse and complex Work Sharing and Adaptation? challenges to overcome. This path is often made more arduous by the intricate and • Plenary Three: Feasibility of Aligning nuanced processes, rules, and considerations Technology Evaluation Processes particular to each jurisdiction, agency, policy and Decision in an Era of Sustainable maker, and health system. Overcoming these Development challenges requires a harmonized framework to examine and evaluate health technologies. We thank the International Scientific Program Alignment of processes throughout the health Committee for its dedication to building a technology lifecycle is crucial. thought-provoking and inspiring program, which not only brings topics new to the Annual Enabling the integration of clinical and Meeting, but builds upon discussions started at policy approaches to health technologies is the previous Annual Meeting to facilitate real dependent upon methods for facilitating timely collaboration between regulators, HTA bodies and funded access to clinical innovation for and clinicians. patients and health professionals; horizontal consistency in approaches for evaluating and We wish you a productive and enjoyable Annual approving health technologies by regulators Meeting experience. Please explore topics, and payers; and better vertical alignment in engage with presenters and exhibitors, and decision-making across all elements in the build connections with colleagues—both new health system involved with regulation, funding, and established. We encourage you to join the implementation, and re-assessment. conversation online using the event hashtag, #HTAi2023Adelaide. The location of this Annual Meeting is particularly in line with these conversations: Thank you for joining us here in Adelaide! many countries in the Asia-Pacific region are experiencing growing interest in health Sincerely, technology assessment and are implementing or re-evaluating the framework guiding Prof. Guy Maddern decision-making and healthcare delivery for its patients and citizens. Furthermore, with Prof. Wim Goettsch legislative developments and financial pressure 11

INTRODUCTION HTAi 2022 International Scientific Program Committee (ISPC) Co-Chairs Prof. Guy Maddern Prof. Wim Goettsch RP Jepson Professor of Special Advisor HTA, Surgery, University of Adelaide, Zorginstituut Nederland Australia and Utrecht University, Netherlands Professor Guy Maddern is the RP Jepson Professor of Surgery at the University of Professor Wim Goettsch, Ph.D. is currently Adelaide, Director of Research at the Basil Special Advisor HTA at the Dutch National Hetzel Institute for Translational Health Health Care Institute He was the Director Research at The Queen Elizabeth Hospital of the EUnetHTA JA3 (2016-2021). and Director, Surgical Research and Directorate and Chair of the Executive Evaluation (incorporating ASERNIP-S) of the Board of EUnetHTA between June 2016 Royal Australasian College of Surgeons. He and March 2018. Since 2019, he also has was trained at the University of Adelaide and had a position as an Associate Professor became a Fellow of the Royal Australasian at Utrecht University (NL) where he is College of Surgeons in 1989. His clinical leading a new H2020 consortium with interests include the development of fifteen partners around Europe, called HTx techniques to manage metastatic hepatic on new methods for Health Technology disease and hepatic approaches to optimize Assessment for personalized medicine resection options. He has also published (2019-2024). Between 2010 and 2013, he widely on new surgical techniques and was the Deputy Secretary of the Medicinal their introduction into surgical practice. Products Reimbursement Committee at the He has over 500 publications in scientific Dutch National Health Care Institute. He is journals, has contributed to over a dozen currently a Director on the Board of HTAi surgical texts and attracted $65 million of (2019-2022). Before joining the National research funding. The evaluation of new Health Care Institute, he worked as a technologies and in particular surgical research manager for the PHARMO Institute technologies is another area of focus and and was responsible for the coordination of interest. Under his supervision, ASERNIP-S numerous pharmacoepidemiological and has been responsible for assessing these outcomes studies for international offices technologies before exposing the Australian of pharmaceutical companies such as population to them and has provided this AstraZeneca, Novartis, Pfizer, and GSK. He service to the Australian and International has a Ph.D. in immunology and advanced community for the past 20 years, and is education in (pharmaco)- epidemiology recognized, nationally and internationally, as and pharmaco-economics. He has more the premier surgical innovation assessment than 100 publications in peer-reviewed group. He is a past President of HTAi and a international journals. past Chair of INAHTA. 12

INTRODUCTION Members • Dr. Izzuna Mudla Mohamed Ghazali, Deputy Director, Malaysian Health • Assoc. Prof. Wendy Babidge, General Technology Assessment Section Manager, Research Audits and (MaHTAS), Medical Development Academic Surgery RAAS, Australia Division, Ministry of Health, Malaysia • Mr. Andrew Bruce, Head of • Dr. Andres Pichon-Riviere, Executive International HTA and Payment Policy, Director, Institute for Clinical Amgen, Australia Effectiveness and Health Policy (IECS), Argentina • Dr. Luciana Ballini, Senior Executive, Regione Emilia-RomagnaItaly, Italy • Ms. Lauren Pretorius, CEO, Campaigning for Cancer, South Africa • D r. Yingyao Chen, Director, NHC Key Lab Of HTA, Fudan University China, • Dr. Jeff Round, Chief Scientific Officer, China International Health Economics, Canada • Dr. Miyoung Choi, Director of Clinical • Mrs. Ann Single, Coordinator / Chair, Evidence Research, National Evidence- Patient Voice Initiative / HTAi Patient based healthcare Collaborating Agency, and Citizen Involvement Interest Group, Korea Australia • Ms. Suadamini Dabak, Economist, • Mr. David Tamblyn, Team Leader, Health Intervention and Technology Adelaide Health Technology Assessment Assessment Program (HITAP), Thailand (AHTA), Australia • Dr. Dalia Dawoud, Senior Scientific • Dr. David Tivey, Research Manager, Adviser, NICE - The National Institute Research Audits and Academic Surgery for Clinical Excellence, United Kingdom (RAAS), Australia • Dr. John Gillespie, Health Economics • Dr. Sophie Werkö, Manager of & Reimbursement Specialist, Abbott, International Relations, the Swedish Australia Agency for Health Technology Assessment and Assessment of Social • Dr. Iñaki Guiterrez Ibarluzea, Director Services (SBU), Sweden of Innovation, BIOEF, Spain • Dr. Suchitra Iyer, Director of Technology Assessment Program, AHRQ, United States of America • Dr. Hong Ju, Senior Principal Lead Specialist, Agency for Care Effectiveness, MOH, Singapore • Prof. Brendon Kearney, Consultant, Royal Adelaide Hospital, Australia • Dr. Iga Lipska, Hospital Based HTA Project Leader, National Health Fund, Poland • Prof. Tracy Merlin, Professor/Director, AHTA | Interim Head, School of Public Health, University of Adelaide, Australia 13

INTRODUCTION About HTAi Health Technology Assessment international HTAi Membership (HTAi) is an open platform for global collaboration that leverages and shares HTAi members are part of an international collective intelligence to improve health network of experts and leaders in the HTA outcomes worldwide. As an international field. Importantly, our membership shares a network of those working to advance and commitment to extending the conversation promote health technology assessment beyond the traditional bounds of industry (HTA), we represent multidisciplinary or professional bodies by including those organizations and individuals from around impacted by the conversations, and those the world. HTAi was founded in 2003, in whose decision making is influenced by the Canada, and has since contributed to the outcomes of HTA research. Our broader global health ecosystem and HTA learning community of members, researchers, through our international Annual Meetings, experts, leaders, patients and policy Policy Forums, Interest Groups, journal makers use HTAi as an open platform for publications and more. collaboration, as we all seek ways to use HTA to improve global health. HTAi is a member-driven organization that represents a variety of stakeholders who Members gain access to the Annual Meeting have interests in HTA, including researchers, and become eligible for an invitation to our policy makers, industry, academia, health Policy Forums. Members are also welcome service providers, agencies and patients to join any of our current Interest Groups. who contribute to balance conversation These unique platforms allow members to around HTA across different areas of partake in face-to-face discussions with practice and jurisdictions. We are governed one another and to be part of the critical by an elected Board of Directors that hail conversations that help inform policy on the from across the globe and are supported use of effective technologies in healthcare by an Executive Committee, Finance and assessment. This important collaboration Audit Committee, Advisory Committees, ensures a balance of ideas from the numerous working groups and the HTAi broad HTA community. Our networking Secretariat. and partnership opportunities have been identified as truly unique by our members and we pride ourselves on bringing the world together to better healthcare through HTA. In the upcoming years, we’ll continue to seek out opportunities to extend our reach to new stakeholders and emerging HTA sectors. Collaborating with emerging parties interested in developing and delivering educational content around HTA will provide more opportunities to expand HTA learning globally. 14

INTRODUCTION HTAi Board of Directors 2022-2023 President Dr. Debjani Mueller Dr. Wija Oortwijn South Africa Netherlands (2022-25) (2021-23) Dr. Wim Goettsch Vice President Netherlands Dr. Rabia Sucu (2022-25) Ukraine (2021-23) Dr. Li Ying (Grace) Huang Taiwan Treasurer (2020-23) Dr. Americo Cicchetti Italy Dr. Franz Waibel (2021-24) Switzerland (2020-23) Secretary Dr. Jo Carol Hiatt Mrs. Vania Canuto USA Brazil (2021-24) (2020-23) Past President Ms. Dimitra Lingri Dr. Iñaki Gutierrez-Ibarluzea Greece Spain (2022-25) (2021-23) Dr. Marco Marchetti Italy (2022-25) Board Observers Policy Forum Chairs Assoc. Prof. Wendy Babidge Dr. Dan Ollendorf Australia USA, HTAi Global Policy Forum Editor-in-Chief, International Chair (2020-24) Journal of Technology Assessment in Health Care Dr. Manuel Antonio Espinoza HTAi Latin America Policy Forum Prof. Tracy Merlin Chair (2022-24) Australia INAHTA Prof. Guy Maddern HTAi Asia Policy Forum Chair (2022-24) 15

INTRODUCTION Interest Groups As a member of HTAi, you are invited to Hospital-Based HTA (HB-HTA) join one or more of the ten Interest Groups • Co-Chair: Rossella Di Bidino, Italy (IGs) to share international experiences and • Co-Chair: Iga Lipska, Poland expertise among HTA users and producers • Technical Officer: Monika Kukla, Poland worldwide. HTA in Developing Countries (DCIG) The IGs serve as professional and scientific • Chair: Debjani Mueller, South Africa forums for all those who undertake and use • Technical Officer: Yves Miel Zuniga, HTA in health care, business, government, Philippines academic institutions and consultancies. The IGs provide a unique environment for Information Retrieval (IRG) HTAi members to network and exchange • Co-Chair: Amanda Hodgson, Canada information, and to collaborate on projects • Vice-Chair: Ingrid Harboe, Norway of mutual interest throughout the year. • Technical Officer: Vacant Members share topic updates, participate in the development of new research and Medical Devices (MDIG) useful materials, and conduct workshops • Co-Chair: Anastasia Chalkidou, UK and training sessions. There are also • Co-Chair: Richard Charter, Switzerland opportunities for IG members to be • Technical Officer: Jarno Suominen, involved in activities directly funded by HTAi. Finland Please feel free to attend any of the IG Patient and Citizen Involvement (PCIG) Business Meetings while in Adelaide; details • Chair: Ann Single, Australia on the timings and locations are available in • Technical Officer: Hadewych Honnè, the Schedule-At-A-Glance and in the app. Netherlands Disinvestment and Early Awareness (DEA) Public Health (PHIG) • Chair: Rosmin Esmail, Canada • Chair: Vacant • Co-Chair: Nora Ibargoyen Roteta, Spain • Technical Officer: Vacant • Technical Officer: Deinzel Uezono, Philippines Real World Evidence and Artificial Intelligence (RWEAI) Early Career Network (ECN) • Chair: Eva Turk, Austria • Chair: Massoud Toussi, France • Technical Officer: Birol Tibet, Turkey • Co-Chair: Elena Petelos, Netherlands • Co-Chair: Dimitra Lingri, Greece Ethical Issues in HTA (ETH) • Technical Officer: Alessandra Blonda, • Co-Chair: Pietro Refolo, Italy • Co-Chair: Bart Bloemen, Netherlands Belgium • Technical Officer: Costanza Raimondi, Italy 16

INTRODUCTION HTAi Policy Forums HTAi hosts three Policy Forums throughout the 2023 Asia Policy Forum will be held in the year: the Global Policy Forum, the Taipei, Taiwan in November. Findings from Asia Policy Forum and the Latin America the most recent Global Policy Forum will Policy Forum. Each Forum is by invitation be presented at this annual meeting during only, bringing together some of the most the panel session. There will also be panel senior representatives in the field of HTA— sessions from the two regional Policy Forum representing industry, HTA agencies and meetings. Please refer to the program payers—to participate in strategic discussions section on HTAi Policy Forum Meetings and surrounding the present state of HTA and its Sessions. development around the world. The Forums provide the opportunity to interact and For more information or questions regarding network with various stakeholders on a one- the Policy Forums, please contact our Events on-one basis, have open group discussions Manager, Ali Powers at [email protected]. around relevant and pertinent topics, and have direct impact on local HTA policies. Topics discussed at the Policy Forums are diverse and complex, considering the pressing policy issues for HTA. Past Forums have tackled topics such as HTA and Decision Making, Real-World Evidence, Access to High Cost Technologies, Horizon Scanning, Value Frameworks, Changing HTA Paradigms, Improving Evidence Production, HTA and Value, Adaptive Approaches to Licensing, and Disinvestment. Reports from all the Policy Forum meetings are published in the society’s official journal, the International Journal of Technology Assessment in Health Care (IJTAHC). This past year saw the 2023 Global Policy Forum in The Hague, The Netherlands. The 2023 Latin American Policy Forum will be held in Santiago, Chile in August and 17

INTRODUCTION HTAi Secretariat The HTAi Secretariat is based in Edmonton, Alberta, Canada and provides professional strategic and managerial support to our Board of Directors, committees and members, while executing all HTAi activities. Health Technology Assessment international (HTAi) 1280, 5555 Calgary Trail, Edmonton Alberta T6H 5P9 [email protected] HTAi.org Melissa Donecz Elizabeth Kendall Manager, Accounting Communications Lead [email protected] [email protected] Marlene Hanke Amren Thakur Manager, Corporate Services Senior Coordinator, Scientific [email protected] Initiatives [email protected] Denise Jarrett Manager, Program Gerardo Cea [email protected] Coordinator, Technology [email protected] Antonio Migliore Breanne Dickhout Manager, Scientific Initiatives Project Coordinator, Events [email protected] [email protected] Alicia Powers Elise Penny Manager, Policy Forums & Project Coordinator, Annual Events Meeting [email protected] [email protected] Tatiana Hagerty Nicola Vicari Senior Coordinator, Coordinator, Scientific Governance & Executive Initiatives Projects [email protected] [email protected] Shelley-Anne Fraser Hana Price Coordinator, Administration Senior Coordinator, Events [email protected] [email protected] 18

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General Information

GENERAL INFORMATION General Information Guide to Adelaide its food and wine, its coastline and hills, and its large defense and manufacturing Adelaide is the capital city of South sectors. Adelaide’s quality of life has ranked Australia, the state’s largest city and the consistently highly in various measures fifth-most populous city in Australia. through the 21st century, at one stage being “Adelaide” may refer to either Greater named Australia’s most liveable city. Adelaide (including the Adelaide Hills) or the Adelaide city centre. The Traditional Owners Cultural information of the Adelaide region are the Kaurna people. The area of the city centre and HTAi acknowledges the land on which surrounding parklands is called Tarndanya in the HTAi 2023 Annual Meeting is held is the Kaurna language. the traditional lands of the Kaurna people, and pay our respects to their elders, past, Adelaide is situated on the Adelaide Plains present, and emerging. We honor the rich north of the Fleurieu Peninsula, between the cultural heritage, spirituality, and deep Gulf St Vincent in the west and the Mount connection to the land and waters that the Lofty Ranges in the east. Its metropolitan Kaurna people have maintained throughout area extends 20 km (12 mi) from the coast generations which have helped shape to the foothills of the Mount Lofty Ranges the cultural identity and history of this and stretches 96 km (60 mi) from Gawler in region. We also pay respects to the cultural the north to Sellicks Beach in the south. authority of Aboriginal people visiting and attending the Annual Meeting from other Named in honour of Queen Adelaide, the areas of South Australia/Australia. city was founded in 1836 as the planned capital for the only freely-settled British Climate province in Australia. Colonel William Light, one of Adelaide’s founding fathers, designed Adelaide has a Mediterranean climate. The the city centre and chose its location close city has hot, dry summers and cool winters to the River Torrens. Light’s design, now with moderate rainfall. Most precipitation listed as national heritage, set out the city falls in the winter months. In June the centre in a grid layout known as “Light’s average high is 16.2 °C (61.2°F) with the Vision”, interspaced by wide boulevards average low 8.3 °C (46.9°F). It is advised to and large public squares, and entirely bring a jacket. surrounded by parklands. Banks and Currency Early colonial Adelaide was shaped by the diversity and wealth of its free settlers, in The official currency in Adelaide is the contrast to the convict history of other Australian Dollar (AUD), but foreign Australian cities. Until the post-war era, it currencies are readily exchanged at the was Australia’s third most populated city. airport and all major banks. It has been noted for its leading examples of religious freedom and progressive Bank debit or credit cards are the most political reforms and became known as convenient means of getting cash at ATMs the “City of Churches” due to its diversity of faiths. Today, Adelaide is known by its many festivals and sporting events, 22

GENERAL INFORMATION (Automatic Teller Machines). All major Restaurants and Gratuity hotels, stores and restaurants accept major credit cards (Visa, MasterCard, and Tipping is not mandatory in Australia, American Express). Cash is useful for smaller but if you wish to leave a tip, the average purchases and street vendors. tipping amount is up to 10 per cent. Some restaurants may charge an automatic Electricity gratuity for large parties. The standard voltage in Adelaide, and the Taxes rest of Australia, is 230 V and the standard frequency is 50 Hz. The power plugs and Australia has a Goods and Services Tax sockets are of type I. (GST) which is equivalent to a VAT. The standard GST rate is 10%. The standard VAT Adapters may be required if you are rate is 18%. travelling from another country. Bear in mind the differences in voltage. Some Mobile Attendee App electrical equipment, such as camera and laptop chargers are usually dual voltage, The official EventsAir event app can be and these should charge up just fine if you downloaded from the following links: have a plug socket converter. Look at the charger and see what it says; for example, Android - https://play.google.com/store/ if your laptop reads ‘100 – 240 volts’, it is apps/details?id=com.eventsair.attendeeapp suitable for use in countries that have a voltage anywhere between 100V and 240V. iOS - https://itunes.apple.com/us/ Please make sure your electronics accept app/the-event-app-by-eventsair/ 220 – 240 volts (V). If your device uses 110 id1142851582?ls=1&mt=8 – 120V, common in North America, you will need a step-down transformer. Upon downloading and opening, the user will be prompted to enter the event code: Insurance HTAi-AM2023 It is strongly recommended that those Do note that the code is case sensitive. attending or participating in HTAi 2023 purchase adequate coverage for health, Delegates can also access the app through travel and private liability insurance before a web browser (Chrome is preferable) via departing their home countries. The https://htai.eventsair.com/attendeeapp/ organisers will not accept responsibility for htai-23-adelaide-am/htai-am2023 personal injury, loss or damage to private, personal property of conference attendants, Once accessed, delegates will have participants and/or accompanying persons. immediate access to basic features like alerts and the agenda. Medical Information Delegates can log in with their account info We hope that everyone stays healthy to access additional features. during the Annual Meeting, but accidents can happen and sometimes you may need medical assistance. Medical care is very well organized in Australia. 23

HTAi Annual Navigating the App: Meeting App Log In: This is where you can log Event Code: HTAi-AM2023 in to the app to access the full benefits. Please use your HTAi log in How to use the app: information. 1. Install the app from one of the provided URL’s. Alerts: Any notices or alerts sent by 2. Open the app and input the event code HTAi- the event organizer will be found here. AM2023 (please note that the code is case sensitive) Agenda: This is the full agenda for 3. Log in using your HTAi log in and app code or the HTAi Annual Meeting. While password. scrolling through sessions you can see timing, room information, Delegates can also access the app through a web speakers and a description. If a browser (Chrome is preferable) via https://htai. session interests you, be sure to eventsair.com/attendeeapp/htai-23-adelaide-am/ favourite it. htai-am2023 Once accessed, delegates will have immediate My Agenda: This will only show access to basic features like alerts and the agenda. sessions which you have favourited/ Delegates can log in with their account info to starred. access additional features. Meeting Hub: A way to connect IOS App: with other event attendees and communicate. Install URL: https://itunes.apple.com/ us/app/the-event-app-by-eventsair/ Sponsors: Where you can access id1142851582?ls=1&mt=8 information and materials provided by this years’ sponsors. Android App: Live Support: You have access to Install URL: https://play.google.com/ virtual support through the app. store/apps/details?id=com.eventsair. Select this to be in contact with one attendeeapp of HTAi’s Secretariat who is happy to assist you. Privacy and Settings: Here you can adjust your privacy settings for the event PP. Log Out: Log out of the app.

GENERAL INFORMATION Annual Meeting Dates and Access and Security Venue Name badges will be provided to Annual Meeting Dates all delegates and participants at the Registration/Check-in Desk. The badge is June 24-28, 2023 your admission pass to all Annual Meeting sessions and the exhibit areas. Delegates Annual Meeting Venue are required to wear their name badge at all times and will not be granted access Adelaide Convention Centre to the conference without them to ensure North Terrace, Adelaide, that access to the conference is properly South Australia 5000, managed. Australia Annual Meeting Tel: +61 8 8212 4099 Registration/Check-in Desk Website: www.adelaidecc.com.au/ At the University of Adelaide, the registration Program at the Adelaide Convention Centre desk is located at the main foyer on the starts with the welcome reception on Ground floor of the Adelaide Health and the Sunday evening and then will be the Medical Sciences (AHMS) Building and will main venue for the Monday – Wednesday be open during the following times: program. Saturday, June 24: 8:00-17:00 Workshop Venue Sunday, June 25: 8:00-15:00 Adelaide Health and Medical Sciences At the Adelaide Convention Centre the (AHMS) Building – the University of Adelaide registration desk is located in the Atrium 4 North Terrace Foyer and will be open during the following North Terrace, Adelaide, times: South Australia 5000, Australia Sunday, June 25: 17:00 – 22:00 Monday, June 26: 07:30 – 19:00 Tel: +61 8 8313 0273 Tuesday, June 27: 07:30 – 19:00 Website: https://health.adelaide.edu.au/ Wednesday, June 28: 07:30 – 12:00 All workshops will take place at the AHMS Annual Meeting Timetable building at the University of Adelaide Please consult the Schedule At-A-Glance Annual Meeting Secretariat in the program section or the App for detailed timing and refreshment breaks. All International HTAi Annual Meeting references to time within this program are Management: noted in Adelaide Central Standard Time (ACST), UTC/GMT +9:30 hours HTAi Secretariat #1280 5555 Calgary Trail, Edmonton Alberta, Canada T6H 5P9 Tel: +1 (780) 448-4881 Email: [email protected] Website: www.htai.org 25

GENERAL INFORMATION Exhibit Area Hours Annual Meeting WiFi The exhibit tables are located in the Complimentary WiFi service is provided by Exhibition Hall (halls F & G) and will be open the conference and available throughout at the following times: the common areas and meetings spaces of the Adelaide Convention Centre. Monday, June 26: 08:00 – 18:00 Tuesday, June 27: 08:00 – 18:00 Annual Meeting Language Wednesday, June 28: 08:00 – 14:00 The official language of the HTAi 2023 Posters Annual Meeting is English and all sessions will be conducted in English. Posters are displayed throughout the Exhibition Hall (halls F & G) and available for Lost Property viewing through the designated conference times. Please report any lost or unattended items immediately to conference staff. Should Additionally, scheduled poster presentations you lose anything while at the Adelaide will take place on Monday - Wednesday, Convention Centre, please enquire at the providing delegates with the opportunity to Annual Meeting Registration/Check-in Desk experience a series of mini-presentations where any recovered lost property will be and ask the poster authors questions about held. their work. Please refer to the Posters section for scheduled presentations. Photographer Speaker Support Room By attending the HTAi 2023 Annual Meeting, the participant understands and provides The Speaker Support Room will be available consent to being photographed or being in the Atrium Foyer (close to the registration recorded by means of video or audio counter and information desk). Speakers tape recording by the organizers, or a are requested to load their slides in the designated representative of the organizers. Speaker Support Room at least two hours These photographs and/or recordings can before their presentation. It is strongly be used, without compensation to the recommended to only use the presentation participant, in any public display, publication laptop provided in the conference rooms. or media, or website, or in any manner or form, and at any time by the organizers in The Speaker Support Room will be open at promotion of the mission to promote the the following times: Annual Meeting. The participant releases the organizers, and their employees, Monday, June 26: 07:30 – 19:00 agents, representatives, associates, Board of Tuesday, June 27: 07:30 – 17:30 Director members and consultants from any Wednesday, June 28: 07:30 – 12:00 liability in connection with the use of such photographic, video and/or audio materials. Recording of any HTAi materials in any type of media is prohibited without prior written consent from HTAi. 26

GENERAL INFORMATION Smoking Policy Patient Lounge Smoking is not permitted in the Adelaide Room Riverbank 2, ACC Convention Centre. Please obey all smoking restrictions and be respectful of the HTAi has incorporated a Patient Lounge environment and neighbourhood. at the Annual Meeting. The Patient Lounge aims to facilitate a patient-friendly Refreshment Breaks and environment to improve the overall Lunch experience of patient delegates. The space is for registered patients to rest and refresh, All refreshment breaks and lunch will be which offers a number of accommodations served in the Exhibition Hall (halls F & G). specific to patient needs. For those attending sponsored symposia or business meetings during lunch breaks, We ask all delegates to respect the Patient a boxed lunch will be available in the Lounge as a space exclusive to patients. The scheduled session rooms. lounge will be accessible to all attendees registered as patient delegates. Delegates who require a special meal due to dietary restrictions/allergies can pick up their meals in the main catering Hall F&G near the entrance. Plant Based / Vegetarians can find their meals in the main buffet. All dietary restrictions and allergies needed to be declared upon registration. If you have not yet made us aware of your dietary resctiction, please visit the registration desk.  Data Accuracy Disclaimer The details in this program are accurate as of June 6, 2023 27

GENERAL INFORMATION Floor Plans The University of Adelaide GRGOroUuNndDFlFoLoOr OR Registration Entrance 1068 Elevators to Main Entrance Escalators to Levels 1-8 from North Terrace Levels 1-3 !!\"\"#11$%sS%Tt&'\"FFlLoOorOR Refreshment & Lunch Breaks Level 1 1059 A 1059 B 1068 Elevators \" (\" #$\"#2$%8%&'\"

GENERAL INFORMATION \"(#$33\"#r$dR%D%F&l'F\"ooLrOOR 3066 29 Elevators 44thTHFloFoLr OOR \" )\"%\"#$%%&'\"\" 4050 A/B Elevators \"

GENERAL INFORMATION \" 5TH FLOOR *\"5%\"t#h$%F%l&o'\"o\" r 5052 A 5052 B Elevators 6TH FLOOR 6th Floor \" +\"%\"#$%%&'\"\" 6052 A 6052 B Elevators 30 \" \"%

,\"77\"%t\"h#T$H%F%loF&'o\"LrOOR GENERAL INFORMATION 31 7052 A/B Elevators 8TH FLOOR \"8th Floor -\"%\"#$%%&'\"\" 8052 A/B Elevators \"

GENERAL INFORMATION Adelaide Convention Centre GGrRoOuUnNdD LLEeVvEeLl WEST CENTRAL EAST Breakout Registration and Gilbert Rooms Welcome Information Suite Reception Counter Elevators to Levels 1-8 LIFT STAIR FOYER FOYER FOYER LIFT E1 E2 E3 STAIR FOYER F STAIR LIFT FOYER FOYER FOYER F ATRIUM L1 L2 L3 ENTRANCE STAIR E1 E3 LIFT L1a STAIR LIFT L1b L2 L3 ESCALATOR FOYER CAR LIFT G2 FOYER G STAIR CD L L FOYER G STAIR & ESCALATOR LIFT FOYER ATRIUM G1 FOYER WEST ESCALATOR M LINK Catering, Speaker MAIN (EAST) Plenary ENTRANCE FOYER N Support ENTRANCE Room M HExhibitions, Room Main STAIR and Posters Entrance O CENTRAL ENTRANCE LIFT I J K LIFTS STAIR LIFT ESCALATOR LLoOwWeERr LLEeVvEeLl WEST CENTRAL STAIR EAST Meeting WEST PROMENADE EAST PROMENADE Room CENTRAL PROMENADE FOYER FOYER FOYER LAWN LIFT R4 R3 R2 STAIR STAIR STAIR LIFT FOYER FOYER FOYER FOYER R4 R3 R2 R1 R8 R7 R6 R5 LIFT R8 R6 FOYER LIFT R8b R7 R6b R5 CAR R1 LIFT STAIR Breakout Patient Meeting Rooms Lounge Room 32

Schedule-at-a- Glance

SCHEDULE-AT-A-GLANCE SScchheedduulele--aAt-ta--AG-lGanlacnece HTAi Business Meetings Social Events Ceremonies Workshops Panel Sessions Plenaries Exclusive Symposia Oral Sessions Saturday, June 24 Sunday, June 25 Monday, June 26 Tuesday, June 27 Wednesday, June 28 08:00 Pre-Conference Opening Ceremony & Plenary II Annual General Meeting Workshop Keynote 08:00-09:15 08:00-09:00 08:30-10:00 08:00-09:00 09:00 Pre-Conference Break Plenary I Break 09:00-09:10 Workshop 10:00-10:30 09:00-10:15 08:30-10:00 Pre-Conference Panel Sessions V Workshop 09:10-10:25 10:30-12:00 Break 09:15-09:25 Exclusive Symposium 09:25-10:40 10:00 Break Refreshment Break & Refreshment Break & Break 10:25-10:35 11:00 10:00-10:30 Poster Session 1 10:15-10:40 Poster Session 2 10:40-11:10 Oral Sessions IV Exclusive Symposium Panel Sessions III 10:35-11:20 Pre-Conference 10:40-11:55 11:10-12:25 Workshop Refreshment Break & 10:30-12:00 Break 11:55-12:05 Break 12:25-12:35 Poster Session 6 11:20-11:50 Lunch / Lunch / Plenary III 12:00 Lunch Lunch IG Meetings 12:05-13:05 Symposia / 11:50-13:05 12:00-13:00 12:00-13:00 IG Meetings / Break 13:05-13:15 Poster Session 3 Closing Ceremony 13:00 Pre-Conference Pre-Conference Panel Sessions I 12:35-13:35 13:05-14:00 Workshop Workshop 13:15-14:30 Break 13:35-13:45 13:00-14:30 13:00-14:30 Orals II 13:45-14:45 14:00 Refreshment Break 14:30-15:00 15:00 Refreshment Break Pre-Conference Break 14:30-14:40 Break 14:45-14:55 14:30-15:00 Workshop 15:00-16:30 Orals I Panel Sessions IV Pre-Conference 14:40-15:40 14:55-16:10 Workshop 15:00-16:30 16:00 Refreshment Break 15:40-16:00 17:00 Exclusive Symposia Break 16;10-16:20 16:00-17:15 Refreshment Break / Poster Session 4 & 5 / IG Break 17:15-17:25 Meetings Panel Sessions II 16:20-17:20 17:25-18:40 Break 17;20-17:30 18:00 Orals III 19:00 17:30-18:30 * Early Career Meet and Greet Welcome Reception 19:00 Conference Dinner 19:30 Please note that times may be subject to change. * By invitation only 34

Program Agenda

PROGRAM AGENDA Summary Agenda Saturday, June 24, 2023 University of Adelaide (UofA) Time Item Room 09:00 – 16:00 Balcony Room West, 08:30 – 10:00 HTAi Board of Directors Meeting (Invitation Holiday Inn Express Only) Adelaide City Centre 10:00 – 10:30 UofA, AHMS Building 10:30 – 12:00 Workshops: 1059A 12:00 – 13:00 WS01 - Research Oriented Market Access for 5052A Adopting High-Cost Therapies – Principles and Practice 4050 A/B WS02 – Introduction to Ethics in Health 1068 Technology Assessment 1059B WS03 – HTA 101: Introduction to Health Technology Assessment 6052 A/B WS04 - Automation Tools to Improve the Speed 5052B of Conducting Systematic Reviews 3066 WS05 - Patient and Citizen Involvement in Health Technology Assessment UofA, AHMS Building Level 1 Foyer WS06 - Patient-Reported Outcomes for Health UofA, AHMS Building Technology Assessment Various UofA, AHMS Building WS07 - Introduction to GRADE for Establishing Level 1 Foyer the Certainty of Evidence in Systematic Reviews and Health Technology Assessment WS08 - An Introduction to Early Health Technology Assessment Morning Break (Workshop attendees only) Continuation of the Workshops Lunch (Workshop attendees only) 36

PROGRAM AGENDA 13:00 – 14:30 Workshops: UofA, AHMS Building 1059B 14:30 – 15:00 WS05 - Patient and Citizen Involvement in Health 15:00 – 16:30 Technology Assessment 6052 A/B WS06 - Patient-Reported Outcomes for Health 5052B Technology Assessment 3066 WS07 - Introduction to GRADE for Establishing the Certainty of Evidence in Systematic Reviews 4050 A/B and Health Technology Assessment 1068 WS08 - An Introduction to Early Health Technology Assessment UofA, AHMS Building Level 1 Foyer WS10 - The Road to Policy and Clinical UofA, AHMS Building Integration in Genomic Medicine, Advanced Various Diagnostics & Advanced Therapeutic Products WS11 - HTAi Interest Group on Rare Diseases – Developing a Workplan Afternoon Break (Workshop attendees only) Continuation of the Workshops 37

PROGRAM AGENDA Sunday, June 25, 2023 University of Adelaide (UofA) Adelaide Convention Centre (ACC) Time Item Room 08:30 – 10:00 UofA, AHMS Building Workshops: 4050 A/B 09:00 – 11:00 10:00 – 10:30 WS12 - A Workshop to Learn About “Why” and 3066 10:00 – 12:00 “How” to Assess the Impacts of Health Technology 10:30 – 12:00 Assessment 6052 B 11:00 – 12:30 12:00 – 13:00 WS13 - HTA of Artificial Intelligence: Experiences 6052 A 13:00 – 14:00 and Challenges 7052 A/B WS14 - Engaging Stakeholders to Strengthen Health systems in Low- and Middle-Income 5052 A/B Countries (LMICs) moving towards Universal Health Coverage 1059 A WS15 - Values in Doing Assessments of Healthcare ACC, Gilbert Suite Technologies (VALIDATE) UofA, AHMS Building WS16 - Advanced Workshop in Information Level 1 Foyer Retrieval: New Challenges and Updated ACC, Riverbank 1 Approaches in Efficient HTA Literature Searching UofA, AHMS Building Various WS17 - HTA 102 Hospital-Based HTA in the Life ACC, Riverbank Cycle Approach Current Scenarios Boardroom UofA, AHMS Building WS18 - Indigenous Populations and Health Level 1 Foyer Technology Assessment – International ACC, Riverbank Collaboration to Improve Knowledge, Health Boardroom Policy and Equity Global Policy Forum Business and Topic Scoping Meeting (Invitation Only) Morning Break (Workshop attendees only) i-HTS/Euroscan Meeting Continuation of the Workshops Global Policy Forum Organizing Committee Meeting (Invitation Only) Lunch (Workshop attendees only) Asia Policy Forum Organizing Committee Meeting (Invitation Only) 38

PROGRAM AGENDA 13:00 – 14:30 Workshops: WS16 - Advanced Workshop in Information 7052 A/B Retrieval: New Challenges and Updated Approaches in Efficient HTA Literature Searching WS17 - HTA 102 Hospital-Based HTA in the Life 5052 A/B Cycle Approach Current Scenarios WS18 - Indigenous Populations and Health 1059 A Technology Assessment – International Collaboration to Improve Knowledge, Health Policy and Equity WS19 - The Newcomer's Guide to HTA: Handbook 4050 A/B for HTAi Early Career Network WS20 - All Things Publishing: Submitting to HTAi's 6052 B Journal (IJTAHC) - What's your Article Type and Hot Topics in Publishing WS21 – Horizon Scanning for Technology 3066 Forecasting WS22 - The Design of Health Technology 6052 A Assessment Processes Using Evidence-Informed Deliberative Processes in Low- and Middle-Income Countries 14:30 – 15:00 Afternoon Break (Workshop attendees only) UofA, AHMS Building Level 1 Foyer 15:00 – 16:30 Continuation of the Workshops UofA, AHMS Building Various 15:00 – 16:30 Policy Forum Advisory Committee Meeting ACC, Riverbank (Invitation Only) Boardroom 16:45 – 17:45 Interest Group Steering Committee Business ACC, Riverbank Meeting (Invitation Only) Boardroom 18:15 – 19:00 Early Career Meet & Greet (Invitation Only) ACC, Gilbert Suite 19:00 – 22:00 Welcome Reception ACC, Halls F&G and Foyer 39

PROGRAM AGENDA Monday, June 26, 2023 Adelaide Convention Centre Time Item Room 08:00 – 08:30 Plenary Room (Hall C) 08:30 – 09:00 Opening Ceremony Plenary Room (Hall C) 09:00 - 10:15 Plenary Room (Hall C) 10:15 – 10:40 Keynote Halls F&G 10:20 – 10:35 Halls F&G 10:40 – 11:55 Plenary 1 Plenary Room (Hall C) 12:05 – 13:05 Refreshment Break Gilbert Suite 12:05 – 13:05 Poster Presentation Session 1 Riverbank Boardroom 12:05 – 13:05 Symposium 1 - Precision Oncology: Aligning Halls F&G 12:05 – 13:05 Innovation & Assessment to Address Patient Access Riverbank 3 12:05 – 13:05 Challenges Riverbank 4 12:05 – 13:05 ‘International Collaboration Roundtable’ hosted by Riverbank 5 13:15 – 14:30 the Australian Government, Department of Health and Aged Care (Invitation Only) Riverbank 3 Latin America Policy Forum Organizing Committee E3 Meeting (Invitation Only) Riverbank 6 Lunch Riverbank 5 HTAi Interest Group Meeting - Ethics Plenary Room (Hall C) HTAi Interest Group Meeting - Information Riverbank 7 Retrieval Riverbank 4 HTAi Interest Group Meeting - Hospital-based HTA Panel Session 1: PN01 - Best Practice Considerations on the Assessment of Robotic-Assisted Surgical Systems PN02 - Coverage with Evidence Development: Can we Align Perspectives? PN03 - HTA & Traditional, Complementary & Integrative Healthcare (TCIH) in Asian-Pacific region PN04 - HTA in Medical Devices PN06 - Outcomes and Lessons from Implementing the International Summary of Information for Patient Groups in Different HTA Systems PN07 - Rare Disorders. Is the Lack of Effect in a Patient-Reported Outcome, Reflecting no Benefit? PN08 - The Value and Impact of Health Technology Assessment: 2023 HTAi Global Policy Forum Summary 40

PROGRAM AGENDA 14:40 – 15:40 PN09 - What is Early HTA and How Can it Facilitate Riverbank 8 Timely Patient Access to Valuable Innovation? E1 15:40 – 16:00 16:00 – 17:15 PN10 - ZEN and the Art of Health Technology Riverbank 8 17:25 – 18:40 Assessment Hall C Riverbank 6 Oral Presentation Session 1: E1 Riverbank 3 OS01 - Innovative Insights in Disease Management Riverbank 4 Gilbert Suite OS02 - Patient Involvement in HTA: Tools & E3 Challenges Riverbank 7 Riverbank 5 OS03 – Global Perspectives on Cost-Effective Halls F&G Cancer Therapies Plenary Room (Hall C) OS04 – Building Global Capacity for HTA Gilbert Suite OS05 – Patient Values, Gender Medicine in HTA: Riverbank 5 Insights from Cancer, Mental Health & Surveys Riverbank 4 OS07 – Healthcare Models: Economic Evaluation Riverbank 7 Riverbank 8 OS08 – Empowering Healthcare Decisions: Equity, Multimorbidity, RWE & AI OS09 – Bridging HTA Regulations & Real-World Practice: Lessons & Future Directions OS10 – Addressing Uncertainty in HTA & Pricing OS11 – Innovations in HTA Research & Practice Refreshment Break Symposium 2 - Value Creation and Efficiency Gains Through Capacity-Enhancing Innovations to Address Workforce Shortage Panel Session 2: PN11 - Balancing Speed and Rigour in Patient Preference Studies: The Key to Better Integration into HTA Decision Making? PN12 - Do We Need Innovative Evidentiary Approaches to Assess Digital Technologies? PN13 - From Global to Local: What Value from Policy Fora in HTA for Patients, Industries and Assessors? PN14 - HTA Driving Use of Registries to Optimize Treatment for Paediatric Spinal Muscular Atrophy PN15 - Health Technology Assessment Reforms: Drivers, Processes, and Motivations Leading to Change. The Case of Australia, England, and Netherlands 41

PROGRAM AGENDA PN16 - How Can We Improve HTA of Genomics? Riverbank 3 Aligning the Academic, Patient and Industry Riverbank 6 Perspectives. Plenary Room (Hall C) PN05 - ICER Thresholds in Reimbursement E3 Frameworks: Challenges and Experiences in the Asia E1 Pacific PN17 - Moving Towards Harmonizing Patient Involvement in Health Technology Assessment (HTA) through Stakeholder Recommended and Valued Processes PN18 - No Time to Waste – Healthcare as an Investment in the Future PN19 - Towards a Joint Capacity Building through the Family of Health Technology Assessment 42

PROGRAM AGENDA Tuesday, June 27, 2023 Adelaide Convention Centre Time Item Room 08:00 – 09:15 09:25 – 10:40 Plenary 2 Plenary Room (Hall C) 10:40 – 11:10 10:45 – 11:00 Symposium 3 - From Data to Health: Enhanced Plenary Room (Hall C) 11:10 – 12:25 Evidence Methods and Practical Applications for HTA and Treatment Access in Prostate Cancer 11:10 – 12:25 12:35 – 13:35 Refreshment Break Halls F&G 12:35 – 13:35 12:35 – 13:35 Poster Presentation Session 2 Halls F&G Panel Session 3: PN20 - Can Regulators and Health Technology E3 Assessment Agencies Sing from the Same Hymn Sheet? Exploring The Benefits and Challenges PN21 - Can the U.S. Adopt a More Comprehensive, Riverbank 8 Coordinated Approach to HTA? PN22 - Capacity Building in Health Technology E1 Assessment across Eastern Europe and Central Asia PN23 - Growing Green: Raising the Importance of Riverbank 5 Environmental Considerations in Health Technology Assessment to Support Sustainable Health Systems PN24 - Hospital-Based HTA: An Additional Value at Riverbank 4 Local Level or is it just a Duplication of Work? PN25 - Hospital-Based HTA for Health Service Riverbank 7 Delivery Models: Comparing, Contrasting and Learning from Experience PN26 - How Can We Better Manage Uncertainty in Plenary Room (Hall C) HTA? Aligning the Academic, Patient and Industry Perspectives. PN28 - Legal Structure for Establishing an HTA Riverbank 6 Organization: Low- and Middle-Income Countries’ Perspective ‘Changing Conversations’ Hosted by the Australian Gilbert Suite HTA Consumer Consultative Committee Lunch Halls F&G Symposium 4 - Counting the Cost – Assessing the Plenary Room (Hall C) True Value of Investing in Cancer Treatments HTAi Interest Group Meeting - Patient and Citizen Gilbert Suite Involvement 43

PROGRAM AGENDA 12:35 – 13:35 HTAi Interest Group Meeting - Medical Devices E3 12:35 – 13:35 Riverbank 4 12:35 – 13:35 HTAi Interest Group Meeting - Disinvestment & Riverbank 3 12:35 – 13:35 Early Awareness Riverbank 1 12:50 – 13:05 Halls F&G 13:45 – 14:45 HTAi Interest Group Meeting - Early Career Network Riverbank 6 14:55 – 16:10 Plenary Room (Hall C) Annual Meeting 2024 International Scientific E3 Program Committee Meeting (Invitation Only) Riverbank 8 Gilbert Suite Poster Presentation Session 3 Riverbank 4 Riverbank 3 Oral Presentation Session 2: Riverbank 5 Riverbank 7 OS12 – RWE & Economic Evaluation in Chronic E1 Diseases Riverbank 6 OS13 – Empowering Patients in HTA: Opportunities and Challenges Gilbert Suite OS14 – Innovative HTA: Disinvestment, Digital E3 Health, Risk Adjustment Riverbank 3 OS15 – HTA Innovations: Machine Learning to Real-World Evidence OS16 – Advancing Healthcare: Repurposing, Adoption & Economic Analysis OS18 – Cost-Effectiveness of Smoking Cessation & Lung Cancer Screening OS19 – Economic Evaluation & Diagnostic Technologies OS20 – Economic Evaluations: Diagnostic & Therapeutic Interventions OS21 –Patient-Centered Care in HTA OS22 – Healthcare Operations & Management Panel Session 4: PN29 - Digital Divide or Inclusion? Effective Deliberation Experiences: Lessons Beyond Global Health Emergencies PN30 - Equity in Health Technology Assessment: Approaches to Incorporate Equity Concerns into Healthcare Decision Making PN31 - Evidence - Interaction - Trust - Confidence PN32 - How to Balance Benefits and Risks on Cellular and Gene Therapies: HTA Perspective from Selected Countries? 44

PROGRAM AGENDA PN33 - HTA Capacity Building in Asia: HTAi Asia Riverbank 4 Policy Forum 2022 Findings PN34 - Policy Implications of Reimbursement Riverbank 8 and Clinical Integration of Complex Innovations, Examples from Cell Therapy and Gene Editing PN35 - Real World Evidence from Rare Disorders’ E1 Registries. A Problem or Part of the Solution to Inform Decisions PN36 - The Highway to Evidence? Re-using and Riverbank 7 Sharing Existing Evidence PN37 - Uncertainty Regarding the Long-term Riverbank 5 Effectiveness of New Therapies in Health Technology Assessment PN38 - What Managerial Skills for Patient Plenary Room (Hall C) Associations Active in HTA? Discussions and Practical Examples 16:20 – 17:20 Refreshment Break Halls F&G 16:20 – 17:20 16:30 – 16:45 HTAi Interest Group Meeting - Developing Riverbank 3 17:00 – 17:15 Countries 17:30 – 18:30 Poster Presentation Session 4 Halls F&G 19:30 – 24:00 Poster Presentation Session 5 Halls F&G Oral Presentation Session 3: OS23 – Economic Evaluations in Healthcare: Gilbert Suite Insights from Systematic Reviews OS25 – Advancing HTA for Global Health: Insights E1 and Roadmaps OS26 – Innovations in HTA: Processes, Perspectives Riverbank 8 and Value OS28 – Empowering Patient Involvement in HTA: Plenary Room (Hall C) Collaborative Approaches & Future Perspectives OS29 – Economic Evaluation in Cancer and Renal Riverbank 4 Disease: Cost Effectiveness Perspectives OS30 – Evaluating Effectiveness and Cost- E3 Effectiveness in Healthcare Interventions OS31 – Advancements in HTA and Healthcare Riverbank 3 Outcomes OS32 – Global HTA: Challenges and Opportunities Riverbank 7 OS33 – HTA & Economic Evaluations Riverbank 6 Conference Dinner (Ticket purchase necessary) Adelaide Oval, Ian McLachlan Room 45

PROGRAM AGENDA Wednesday, June 28, 2023 Adelaide Convention Centre Time Item Room 08:00 – 09:00 Plenary Room (Hall C) 09:10 – 10:25 Annual General Meeting (AGM) Riverbank 6 09:10 – 10:25 Panel Session 5: Riverbank 3 10:35 – 11:20 PN39 - Estimation of lifetime survival function for Riverbank 7 health technology assessment (HTA): Methods and empirical examples E1 PN40 - Evaluating New Genetic and Genomic Tests E3 in Health Technology Assessment: How to Define and Measure Value? Plenary Room (Hall C) Riverbank 4 PN41 - Exploring the Implications of Accelerated Access Pathways for Promising New Medicines on Riverbank 5 HTA and Patient Access Gilbert Suite PN42 - How Can We Make Better Use of RWE for Gilbert Suite HTA? Aligning the Academic, Patient and Industry E3 Perspectives. Plenary Room (Hall C) Riverbank 5 PN43 - Managed Entry Agreements for High-Cost, One-Shot Curative Therapies? - A Calculation Tool to Determine their Desirability PN44 - Patients as Active Contributors to Horizon Scanning PN45 - RWE: Experiences & Challenges for Decision Making in Latin America - 2022 Latin America Policy Forum Findings PN46 - Using Quantitative Patient Preference Data to Assist HTA Decision-Making Is HTA Ready for GPT/AI Large Language Models? A Participative \"Fishbowl\" Session Oral Presentation Session 3: OS34 – Innovations in HTA: Expert Elicitation, Disease Progression Analysis & Diagnostic Pathways OS35 – Health Initiatives: Knowledge, Screening, and Economic Impact OS36 – Impact of HTA: Insights from Healthcare Systems, Hospitals, and Stakeholders OS37 – Future of HTA: Policy, Challenges & Digital Innovation 46

PROGRAM AGENDA 11:20 – 11:50 OS38 – Advancing HTA: Bridging Data Access & Riverbank 7 11:25 – 11:40 Proportional Approaches and Patient Outcomes 11:50 – 13:05 Riverbank 3 13:05 – 14:00 OS39 –Assessing Medical Interventions Riverbank 6 Riverbank 4 OS41 – Local Economic Evaluation and HTA Halls F&G OS42 – Analyzing HTA in Brazil: Decision Criteria, Halls F&G RWE & Medication Exclusion Hall C Plenary Room (Hall C) Refreshment Break Poster Presentation Session 6 Plenary 3 Closing Ceremony and Presentation of Awards Insight meets action at the point of possibility. Getting the most out of your robotics program—that’s Intuitive Learn more at intuitive.com Important safety information For important safety information, please refer to www.intuitive.com/safety. For a product’s intended use and/or indications for use, risks, full cautions and warnings, please refer to the associated User Manual(s). © 2022-2023 Intuitive Surgical Operations, Inc. All Rights Reserved. PN1097904-US RevC 04/2023 47

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Feature Sessions

FEATURE SESSIONS Feature Sessions Sunday, June 25 Monday, June 26 Welcome Reception Opening Ceremony & Keynote 19:00 - 22:00 Adelaide Convention Centre 08:00 – 09:00 Halls F&G, Foyer F Adelaide Convention Centre Plenary Room (Hall C) Join us in welcoming colleagues and friends from around the world at the Adelaide • Welcome address on behalf of the LOC. Convention Centre with its beautiful Prof. Guy Maddern, Australia, and evening view. Network with international Dr. Li Ying (Grace) Huang, Taiwan attendees and start engaging conversations to revisit throughout the Annual Meeting. • Opening address from the Australian Minister of Health and Aged Care, A complimentary ticket to the Welcome Dr. Mark Butler, Australia Reception is included with every full Conference Registration. Please pre-register • Welcome on behalf of HTAi, for your complimentary ticket. Dr. Wija Oortwijn, HTAi President, the Netherlands • Welcome address by the ISPC Co-Chairs Prof. Guy Maddern and Prof. Wim Goettsch, Australia • Keynote presentation, Dr. Sam Roberts, United Kingdom Sam Roberts is the Chief Executive of the National Institute for Health and Care Excellence. She has worked in healthcare for 20 years in a combination of clinical, operational, private sector and academic roles. She originally trained as a doctor before undertaking an MBA and joining McKinsey and Company. Her focus for the last 15 years has been on improving quality of clinical care and supporting uptake of innovation - as Head of Operations at a large teaching hospital in London (UCLH), Director of Innovation, Research and Life Sciences at NHS England and Improvement and Chief Executive of the Accelerated Access Collaborative. Prior to joining NICE she invested in early stage digital health 50