integral proteins

List of Membrane Proteins Membrane proteins include transmembrane proteins that span across the membrane, Monotypic/peripheral membrane proteins that attached to the lipid bilayer or other integral proteins and peptide. The reason that membrane proteins studies are extremely important is that they are targets of over 50% of all modern drugs. It is estimated that 20-30% of all genes in most genomes encode membrane proteins. However, such proteins are inherently difficult to purify and characterize. The production of membrane protein is an urgent issue to handle with and optimize. Backed by a team with extensive experience in membrane protein production, Creative Biostructure can express and purify membrane proteins that are currently unavailable in the market (e.g., GPCR, ion channels, transporters, enzymes and viral targets). Following is a list of membrane protein production provided by Creative Biostructure. Transmembrane Protein Production 5-Lipoxygenase- Hypoxia-induced Proteins Aldehyde Dehydr Activating Protein Immunoglobulins Ammonia and Ure ABC Transporters Insulin receptor FMN-linked Oxid ACBP Integrins Leucine Rich Re Amyloid beta (A4) Ion channel Containing Tran Bcl-2 Inhibitors MAPEG Leukotriene C4 BNIPs MFS Lysosome-associ CAAX protease MinK Family glycoprotein Cytochromes P450 MPPs Major Intrinsic E-NPPs Peptidase AD superfamily EPHA1 Peptidase Family M48 Microsomal pros EPHA2 Peptidase MA synthase EPHA3 Protein Jagged N-(deoxy)ribosy EPHA4 Receptor-type Kinases Membrane Protei Fatty Acid SNARE Complex Neutral/alkalin Desaturases Sulfatases Oligosaccharyl Gamma secretase TNF receptor Pentameric Liga Glucose transporter Transmembrane Proteins 14 Channels Glycophorins Transporter Rhodopsin-like GPCR TROBP pumps HER2/ErbB2 VEGF receptors Single-helix AT HER3/ErbB3 Squalene/ phyto HER4/ErbB4 Stearoyl -CoA d HSD-11β Stannin (SNN) M T-cell Surface Zeta Chain

Tetratricopepti Alpha-Helical R Transmembrane P binding Rossman Monotypic/Peripheral Protein Production Alpha/Beta-Hydrolase FYVE/PHD Zinc Finger Protein Phosphatidylino Annexins Galactose-Binding Domain-Like Kinase Bet V1-Like Protein Protein PLC-like Phosph C1 Domain-Containing Glycolipid Transfer Protein Phosphotyrosine Protein Immunoglobulin-Like Superfamily (E Phosphatases II C2 Domain-containing Set) Protein P-Loop Containi Protein Lipocalin Triphosphate Hy CoA-Dependent Lipoxygenase Protein kinase Acyltransferases PGBD superfamily PX Domain-Conta CRAL-TRIO Domain- PH Domain-Like Protein Saposin Containing Synuclein Protein Transcriptional DNase I-like protein Fibrinogen Membrane Protein Peptides Production Amyloid Beta-sheet Peptide Fragments of Transmembrane Peptide fragmen Peptides Protein proteins Membrane Anchor Helices of Peripheral Proteins Our scientists will assist you in all project stages evaluation, planning and execution. Each project is tailored to the customer’s specifications of scale, purity, analytical characterization and activity. We help our customers plan their projects in the most cost efficient manner. Please feel free to contact us for a detailed quote. References

1. Johnson J., Cornell B. (1999). Amphitropic proteins: regulation by reversible membrane interactions. Mol. Membr. Biol. 16: 217-235 2. Overington J., Al-Lazikani B., Hopkins A. (2006). How many drug targets are there? Nat. Rev. Drug. Discov. 5: 993-996 Related Sections Services: • Cell-Based Membrane Protein Expression Services • Cell-free Membrane Protein Expression • VLP Construction