TYPES OF DNA AND RNA SEQUENCING

Write date here TYPES OF DNA AND RNA SEQUENCING https://tekmatic.com

AgendaSequencing is a crucial element of the process of discovering and studying genetics. It’s also changing rapidly, which is why we’ve created this list of useful information describing the various DNA & RNA sequencing and epigenomics. Suppose you like this list of helpful DNA and RNA sequencing types. In that case, you may be interested in downloading the free Next Generation Sequencing Guide that includes this information, the latest background of NGS sequencing, the steps to sequencing, and more.

Types of DNA Sequencing 1. Whole Genome Sequencing (WGS) Whole genome sequencing can be used to determine the sequence of the genome that an animal has. In addition, WGS can be used to identify variations (mutation) prevalent within populations of organisms and to link genetic variations with diseases through genome-wide association research (GWAS). A GWAS conducts WGS on two groups and then compares the differences in traits with genetic variations to link traits with known variants. WGS was first used for diagnostic purposes in 2009. However, time and cost have limited its application in this field. Since the cost of WGS has declined to increase, it’s becoming more popular as an instrument for diagnosing. After achieving a “$1000 genome “$1000 genome”, multiple companies are working toward the goal of achieving a “$100 genome” “$100 genome”.

2. Targeted sequencing Targeted NGS lets users analyze specific parts of the genome to conduct in-depth analyses more quickly and cost-effectively than complete genome sequencing. Targeted sequencing can identify the existence of novel and well-known variants in the area of interest. It typically produces less information than WGS, which makes it easier to manage the analysis. Many methods of targeted sequencing are suitable to the specific needs. The most well-known techniques are hybridization capture amplicon sequencing and molecular-inversion probes (MIPs). Check out the Targeted Sequencing Guide to learn more about the in-depth differences between hybridization capture and amplicon sequence.

3. Whole exome sequencing (WES) Whole exome se quencing can identify all the protein-coding genes that are part of the genome. Concentrating on exons that code for proteins (and exclusion of other parts in the genome) could reduce the expense and time involved in sequencing because exons make up only one percent part of the genome. The variations in exons that encode proteins can be responsible for various diseases; therefore, this type of sequencing is usually enough for diagnostic purposes. WES is a better method of mapping the variants that are not common in the general population to help identify the causes of complex diseases. It’s also an excellent alternative for discovering research. WES is especially useful in research on cancer and is currently used for cancer diagnosis. The information gathered from WES can give insight into the future and personalized treatment options. WES is typically performed using hybridization probes rather than amplifiers.

Thank You Address:- 7316 N Alpine Road Loves Park, IL 61111 Phone:- 815.282.1775 Website:- https://tekmatic.com