Calcium Plus English Version

Contents Natural Calcium .……………………………………………………………………1 Bone Health ………………………………………………………………………..2 Regulates Blood Pressure ……………………………………………………..3 Prevents Colon Cancer ………………………………………………………..5 Combats Kidney Stones And Kidney Disease ……………………….6 Promotes Weight Loss ………………………………………………………7 Eases PMS Symptoms ………………………………………………………7 Promotes Dental Health …………………………………………………..9 Calcium Supplements: Organic Vs Inorganic …………………….12 Why Vitamin D3 & K2 Important? …………………………………12 The Role Of Vitamin D ………………………………………………..13 The Role Of Vitamin K2 ……………………………………………..13 Milk Calcium Benefits ………………………………………………..15 Natcal Is The Best Calcium Supplement! …………………….17 Phosporus Essential Mineral For Bone! …………………….17

NATURAL CALCIUM More than 99% of your total body calcium is stored in your bones and teeth, where it supports their structure and is ready to be called into action for many other critical functions. A few of these calcium functions are muscle contraction, the secretion of hormones and enzymes, and sending messages through the nervous system. The amount of calcium in your body fluid and tissues is closely regulated so that these vital body processes function efficiently. Therefore, it is particularly important to consume enough calcium (and its helper minerals and vitamins such as magnesium, vitamins D3, K2, C, boron and trace minerals). When your calcium intake is low or is poorly absorbed, bone breakdown occurs because the body must use the calcium stored in bones to maintain more urgent functions — such as generating a heartbeat! Page 1

THE TOP 7 CALCIUM HEALTH BENEFITS 1. BONE HEALTH Research shows that brittle bones, and increased osteoporosis risks, are found most often in postmenopausal women (because of decreased estrogen). It is especially prevalent in those who are thin, less active, drink excess alcohol and/or take certain medications such as anti-seizure drugs, some steroidal drugs (glucocorticoids), sleeping pills, and breast cancer drugs. However, traditional rock-based calcium supplements (their labels read: calcium carbonate and calcium citrate) have only ever been shown to slow down bone loss. One of the reasons they are ineffective is that they are a single nutrient solution to a multi-nutrient problem. Your bones need much more than just calcium, or calcium and vitamin D. In fact, there are 13 vitamins and minerals that your bones need to stay healthy and strong. The 13 you need are calcium, magnesium, boron, copper, manganese, potassium, phosphorous, nickel, vanadium, zinc, silicon, selenium, strontium – and their bone-promoting actions. Page 2

2. REGULATES BLOOD PRESSURE Calcium is important for healthy blood pressure because it helps blood vessels – arteries, veins, and capillaries – tighten and relax when they need to. That changes the flow of blood through these long strings of channels in your body. People who eat a lot of processed and canned foods or who take certain medications (that deplete these minerals) are at risk, says the director of the Division of Hypertension at the Massachusetts General Hospital Heart Center. According to Harvard University’s 2014 report, key minerals to help control blood pressure include calcium, magnesium, and potassium; and consuming these specific minerals on a regular basis plays a major role in blood pressure control. Linus Pauling Institute – a specialized health and nutrition research institute based at the Oregon State University– reports a meta-analysis of 23 scientific studies that show calcium intake is linked to lowered blood pressure (Allender, 1996). The analysis showed a 0.34 mmHg reduction in systolic blood pressure, and a 0.15 mmHg reduction in diastolic blood pressure per 100 mg of calcium consumed daily. What’s more, further research shows that when you consume over 1,000 mg of calcium a day, the effect on your blood pressure is greater. A review of 16 trials and over 3,000 participants showed that Page 3

consuming at least 1,000 mg of calcium a day reduced systolic blood pressure by 1.14 mmHg. But when calcium intake was increased to 1,500 mg a day, systolic blood pressure was reduced by 2.79 mmHg. However, in other research, like a 2008 study determining the effect of calcium and vitamin D supplements on the blood pressure of over 36,000 women, results did not show any effect. Why? It may be because the type of calcium used was the most common, cheapest, rock-based type (calcium carbonate) distributed to such a large group. The combined effect of nutrients including calcium, magnesium, potassium, vitamins K and D from food has been found to offer direct benefits to blood pressure. The most well-known research is called DASH (Dietary Approaches to Stop Hypertension) by the National Institutes of Health. It found that the combination of abundant fruits and vegetables and calcium supplementation decreased blood pressure. Page 4

3. PREVENTS COLON CANCER The evidence is clear that consuming a healthy balanced diet that includes nutrients like Vitamin B6, calcium and magnesium, and decreasing your consumption of red meats and alcohol create a substantial way to protect against developing colorectal cancer. Calcium seems to protect people from developing the polyps that can lead to colorectal cancer. The largest survey that showed calcium benefits was the 2002 Nurses’ Health Study and Physicians’ Health Study of 135,000 men and women. The authors found that those surveyed who consumed 700-800 mg calcium per day had a 40% to 50% lower risk of developing this cancer (Wu, 2002). Even a 2015 study conducted in Korea, where the population tends to eat a lot of vegetables, found that they needed to increase calcium intake to reduce the risk of colorectal cancer in men and women (Han, 2015). Page 5

4. COMBATS KIDNEY STONES AND KIDNEY DISEASE Kidney stones are crystallized deposits of calcium and other minerals in the urinary tract. Calcium oxalate stones are the most common kidney stones. High calcium intake was previously thought to contribute to developing these kidney stones. But studies now show that higher calcium in your diet (in addition to potassium and magnesium) actually decreases the risk of getting kidney stones (Hall, 2001). Chronic kidney disease, meaning that the kidneys are damaged and can’t filter blood like they should, is associated with imbalances of calcium. And although high calcium intake through traditional supplements is not advised, ensuring that there is adequate calcium in the diet is vital to those with the disease. (Kidney disease is often a result of having diabetes or high blood pressure.) Calcium may also benefit those with kidney disease complications such as parathyroid gland disorder (hyperparathyroidism). Parathyroid glands control the amount of calcium in your blood and bones. A 2002 study showed that calcium supplementation reduced parathyroid disease after only 4 weeks, and also increased bone density in those with hyperparathyroidism (Jorde, 2002). Page 6

5. PROMOTES WEIGHT LOSS According to science, within fat cells, it is the level of calcium that changes the balance between making fat and breaking it down. And when calcium levels within cells are high, this causes fewer fat cells to form. High-calcium intake may also reduce calcium concentrations in fat cells by lowering the production of two hormones (parathyroid hormone and an active form of vitamin D), which in turn increases fat breakdown in these cells (Shi, 2001). In addition, calcium from food or supplements may bind to small amounts of dietary fat in the digestive tract and prevent its absorption, carrying the fat out in faeces (Parikh, 2003). 6. EASES PMS SYMPTOMS Premenstrual syndrome is partly due to changes in estrogen and progesterone levels during the menstrual cycle. It is also caused by chemical fluctuations in the brain, including reduced amounts of your happiness and get-up-and-go neurotransmitters called serotonin and dopamine. Yet what causes these? Deficiencies of nutrients including calcium have been found to substantially influence these changes. Page 7

Among all the supplements used to treat PMS, calcium has some of the strongest evidence to back its benefits (Bocchieri, 2008). Therefore, be sure you’re getting enough calcium; it’s important to note that most of the studies done on calcium used supplements, not just calcium in food. A 2000 study called Micronutrients and PMS: the case for calcium states, “The similarity between the symptoms of PMS and calcium deficiency is remarkable. Clinical trials have found that calcium supplementation effectively alleviates the majority of mood and body symptoms of PMS (Thys-Jacobs, 2000). Ovarian hormones influence calcium, magnesium and vitamin D metabolism. Estrogen regulates calcium metabolism, calcium absorption and parathyroid gene secretion, and these trigger menstrual cycle fluctuations.” In a new 2017 study published in Obstetrics & Gynecology Science, researchers gave women with PMS a low dose (500 mg) of calcium every day for 2 months to see if their PMS severity changed. They found significant differences in both months’ menstrual cycles especially for lower levels of anxiety, depression, water retention and body changes in the calcium group (Shobeiri, 2017). Research from 2015 published in Health Promotion Perspective found an association between premenstrual syndrome and Page 8

several nutrient deficiencies. “There were significant differences in dietary intake of calcium, magnesium, and potassium in the group experiencing PMS, and vitamin D levels were also lower than the normal range (Saeedian, 2015).” Whether you experience abdominal pain, cramps, cravings, bloating, headaches, nausea, mood swings or irritability, you can reduce them naturally! Before reaching for prescription or NSAID medication, consider dietary changes, detox therapies, herbal remedies and nutritional supplements that can work wonders for these symptoms. 7. PROMOTES DENTAL HEALTH Calcium intake during childhood and adolescence is still thought to be most important for continued dental health as an adult. And a hereditary calcium deficiency may contribute to poor teeth as an adult. Yet nutrition may still play a role in oral health throughout life. By supplying your body with the best nutrients to reduce inflammation, prevent gum disease, and improve the health of your oral bone, you may be able to keep that sensational smile longer! A 2011 study published in the Journal of Periodontology found that patients with chronic periodontal disease who took both Page 9

vitamin D and calcium supplements for a year (400 IU/day of vitamin D and 1,000 mg/day of calcium) had better dental health than patients who didn’t take those supplements (Garcia, 2011). A 2001 study in the American Journal of Medicine states that oral bone and tooth loss are correlated with the bone loss in other areas of the body in people aged 65 and older. After examining the number of caries (cavities) and amount of periodontal disease in 145 people after five years of taking a calcium and vitamin D supplement, the researchers found that, indeed, higher levels of calcium and vitamin D did have a beneficial effect on keeping more teeth. “Now we know that supplementation may improve tooth retention, along with routine dental care and good oral hygiene,” said lead author Elizabeth Krall, MPH, PhD, a researcher at Tufts University Nutrition Research Center (Krall, 2001). A 2012 study found that men getting the most calcium from dairy foods had the healthiest teeth (Adegboye, 2012). The researchers followed 432 Danish adults (30–60 y old) over 12 years to see if their diet influenced their dental health. In men, eating substantially more dairy foods high in calcium was definitely associated with decreased tooth loss even after considering amounts that they smoked, drank alcohol, ate sugar, used supplements, had oral dryness (a cause of dental decay), Page 10

and levels of good bacteria in the mouth (which helps prevent decay). Page 11

CALCIUM SUPPLEMENTS: ORGANIC VS INORGANIC The human body can only recognize and utilize one type of calcium: Organic calcium. This bio-available type of calcium found in milk, fruits (many citrus), grains, vegetables and algae. The physical characteristic of organic calcium is the only available form that the body needs and uses. Calcium carbonate & Calcium Citrate are the traditional type of calcium supplement that has been available for years. It is rock- based, which means it is made from rock - particularly limestone or marble. Yes, they are made from actual rocks. That means they’re poorly absorbed and may cause harmful effects to your health (you’re a human, not a building!). You’ll see rock-based calcium supplements with the names ‘calcium carbonate’ or ‘calcium citrate’ on their labels. Unfortunately, 90% of calcium supplements that are available today are of this type. WHY VITAMIN D3 & K2 IMPORTANT? When it comes to calcium metabolism, vitamins D and K work together. Both play important roles. Page 12

THE ROLE OF VITAMIN D One of the main functions of vitamin D is to maintain adequate calcium levels in the blood. There are two ways in which vitamin D can achieve this: • Improving calcium absorption: Vitamin D enhances the absorption of calcium from the food you eat (Aloia, 2014). • Taking calcium from bone: When you don't consume enough calcium, vitamin D maintains its blood levels by drawing on the body's main calcium supply — your bones (Eisman, 2015). THE ROLE OF VITAMIN K2 As mentioned above, vitamin D ensures that your blood levels of calcium are high enough to meet your body's demands. However, vitamin D does not fully control where the calcium in your body ends up. That's where vitamin K2 steps in. Vitamin K regulates calcium in your body in at least two ways: • Promotes storage of calcium into the bone: Vitamin K2 activates osteocalcin, a protein that promotes the accumulation of calcium in your bones and teeth (Hauschka, 1986). Page 13

• Reduces calcification of soft tissues: Vitamin K2 activates matrix GLA protein, which prevents calcium from accumulating in soft tissues, such as the kidneys and blood vessels. Recent scientific evidence suggests that elevated consumption of calcium supplements may raise the risk for heart disease and can be connected with accelerated deposit of calcium in blood- vessel walls and soft tissues (Maresz, 2015). In contrast, vitamin K2 is associated with the inhibition of arterial calcification and arterial stiffening. An adequate intake of vitamin K2 has been shown to lower the risk of vascular damage because it activates matrix GLA protein (MGP), which inhibits the deposits of calcium on the walls. Vitamin K deficiency results in inadequate activation of MGP, which greatly impairs the process of calcium removal and increases the risk of calcification of the blood vessels. An increased intake of vitamin K2 could be a means of lowering calcium-associated health risks (Maresz, 2015). Page 14

MILK CALCIUM BENEFITS The beneficial effect of milk calcium, which makes it superior to other calcium sources, becomes apparent when comparing the effects on bone mass increase. The bioavailability of calcium from a food source is best evaluated by measuring its effect on changes in bone mass over time. Studies have shown that the gain in bone mass density obtained by supplementation with milk calcium is still present years after the supplementation has ended (Bonjour, 2001). This is opposed to supplementing with inorganic calcium, wherethe gain in bone mass density is reversed after withdrawal of the supplementation (Lee, 1996., Lee, 1997., Slemenda, 1997). Page 15

A study in which prepubertal girls consumed milk-derived Calcium fortified foods for 12 months showed significant increases in bone mass density compared to the non- supplemented controls (Bonjour, 1997). A follow-up study of the same girls showed, that the increment in bone mass density in the calcium supplemented girls obtained during the intervention was still present more than 3 years after the cessation of the calcium supplementation (Bonjour,2001). These findings are supported by a 2-year intervention study of dairy food supplementation in teenage girls. One year after the supplementation had ended, the bone mineral density of the girls was re-examined, and results showed that the significant difference between the supplemented girls and controls was still maintained (Smart, 1998). In conclusion, the studies of bioavailability of calcium from milk compared to that of inorganic calcium have shown that the absorption of milk calcium is as good as that of other calcium sources. It is in relation to the effects on increasing bone mass that milk calcium proves itself to be superior to inorganic calcium sources. In opposition to this, bone mass increments obtained by supplementing with inorganic calcium have been shown to reverse to baseline when supplementation with calcium was withdrawn. Page 16

NATCAL IS THE BEST CALCIUM SUPPLEMENT! 1. Trademark and Registered Natural Milk Calcium source from Denmark. 2. Milk Calcium is KOSHER & HALAL certified. 3. Very strong R&D team and backed by strong Scientific Research & Evidences. 4. Optimised Formulation for Optimum Benefits (Milk calcium powder contains Calcium, Potassium & Zinc). Fortified with Magnesium, Vitamin D3 & Vitamin K2, for best bioavailability and functionality. 5. NO fillers, preservatives, artificial flavoring / coloring! PHOSPORUS ESSENTIAL MINERAL FOR BONE! Bone minerals consist of calcium phosphate, and phosphorus is as important as calcium in supporting bone augmentation and maintenance. Although typical adult diets contain abundant phosphorus, some groups of the population may have phosphorus intakes lower than recommended (e.g. vegetarians, people on weight loss diets and the elderly) and for those people high calcium intakes from supplements without any phosphorus may have negative effects on bone health (Heaney, 2004). Page 17

Regarding growth, a recent animal study has documented the co-dependence of calcium and phosphorus for growth and development. Shapiro and Heaney (2003), conclude the following: \"If the diet is low in phosphorus, calcium supplementation alone will be inadequate and may even aggravate the deficiency. In these circumstances, optimal total nutrition, but at the very least a phosphorus calcium source, would be preferable compared to a supplement providing calcium alone. Today the most widely used calcium supplement is calcium carbonate, which does not contain any phosphorus. Milk calcium contains 460 mg phosphorus per 1000 mg calcium. This makes Milk Calcium an excellent source of both calcium and phosphorus. Page 18

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density during the development of peak skeletal mass.” J Bone Miner Res 12:676-82 (1997). Smart EJ, Gilchrist NL, Turner JG, Maguire P March R, Hooke and Frampton CM. “Teenage girls dietary intake attitude toward dairy products, and bone mineral density one year after the cessation of a dairy product food supplement study.” Nutritional aspects of osteoporosis 97. New York: Springer Verlag; p.42-49 (1998). Thys-Jacobs S. Micronutrients and the premenstrual syndrome: the case for calcium. J Am Coll Nutr. 2000;19(2):220-227. Wu K, Willett WC, Fuchs CS, Colditz GA, Giovannucci EL. Calcium intake and risk of colon cancer in women and men. J Natl Cancer Inst. 2002;94(6):437-446. doi:10.1093/jnci/94.6.437 Page 22