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ADC Linker - Development and Challenges
The ADC linker molecule has a major influence on the fate of ADCs. The linker connects the antibody and the cytotoxic payload. The linker imparts ADCs with (1) high stability in the circulation, and (2) specific release of payload in the target tissue. These seemingly contradictory requirements of stability and release lead to the major challenge in the development of linkers.

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ADC Linker - Development and Challenges

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