Brigham and Women's Hospital Department of Surgery Harvard Medical School External Review 2017-2021

Brigham and Women’s Hospital productive group of more junior her risk of breast cancer,” Dr. is leading the way in expanding faculty members in research, teaching King said. “The B-PREP program the boundaries of breast cancer and clinical care.” is unique because it resides in an knowledge and developing more ambulatory breast center at a general precise treatments. Tari A. King, All three women came to the hospital, so we are able to identify MD, Elizabeth Mittendorf, MD, Brigham after 10 to 15 years at other a broader population of women at PhD, and Andrea Pusic, MD, have pre-eminent cancer centers—Dr. risk—specifically those who are not established a breast cancer surgery, King and Dr. Pusic from Memorial already seeking services from the reconstruction and research program Sloan Kettering Cancer Center and cancer center.” that spans the entire continuum Dr. Mittendorf from the University of of the disease, with world-class Texas MD Anderson Cancer Center. “Patients come to the expertise in surgical oncology, plastic Comprehensive Breast Health Center and reconstructive surgery, cancer “The fact that these international with a range of breast complaints, pathology and diagnostic imaging— leaders in their fields are all women, including breast lumps, pain, all in collaboration with their medical and all professors of surgery at infections, imaging abnormalities, and radiation oncology colleagues at Harvard Medical School, and that nipple discharge or high-risk breast Dana-Farber Cancer Institute (DFCI) each has been honored with an lesions, such as lobular carcinoma in and researchers at Harvard Medical endowed chair, is important,” Dr. situ,” Dr. King explained. The typical School (HMS). Doherty explained. “Over half of our high-risk clinic model that focuses general surgery trainees are women, on patients with known breast cancer The Leadership Team as are many of our junior faculty risk factors misses opportunities to members. I hope that it is inspiring intervene with preventive strategies “Building great programs often and enabling for them to see women for many additional women at requires recruiting visionary leaders who have succeeded, and been increased risk for breast cancer. who can assemble a critical mass of recognized as succeeding, along paths talented people,” Gerard M. Doherty, that they might choose to follow.” B-PREP offers a customized MD, chair of the Department of risk assessment program that Surgery, said. “Dr. Tari King joined Personalized Breast includes traditional breast cancer the Department of Surgery in 2015, risk factors, such as family history and it has been her determination and Cancer Care and prior high-risk lesions, as well enthusiasm to recruit critical partners as emerging risk factors, such as with complimentary skill sets that Dr. King, a nationally recognized lifestyle and personal behaviors. have made this the best breast surgery expert in lobular carcinoma in situ, B-PREP highlights modifiable risk program in the country.” serves as chief of the Division of factors and opportunities for focused Breast Surgery at the Brigham and behavioral changes in this broader “In 2018, we were able to recruit chief of Breast Surgery at Dana- population of women at increased Dr. Elizabeth Mittendorf to lead the Farber/Brigham and Women's Cancer risk. Through B-PREP, women receive research efforts of the Division of Center. tailored screening recommendations, Breast Surgery and the broader Breast expedited referrals for genetic Oncology Program and Dr. Andrea Dr. King developed and leads testing, interventions geared toward Pusic to lead the Division of Plastic the Breast Cancer Personalized risk reduction (e.g., exercise, weight and Reconstructive Surgery, because Risk Assessment, Education and management, dietary suggestions), Tari made the opportunity to do Prevention (B-PREP) Program, housed education about risk reducing something special very clear,” Dr. in the Brigham Comprehensive Breast medications and opportunities to Doherty added. “Together, these three Health Center—an outpatient clinic participate in novel clinical trials. have nurtured an extraordinarily that cares for nearly 4,000 women and men every year with various breast- B-PREP’s experienced and related concerns. compassionate clinical care team also “Every woman should understand ...these international leaders in their fields are all women... GERARD DOHERTY, MD BWH DOS 29

includes medical oncologists, nurse research priorities and then bringing on four key priorities: Prevention practitioners, physician assistants those research findings back into the and early disease, patient-centered and a social worker to help women clinic to inform patient care.” outcomes, tailored local-regional understand their breast cancer therapeutic strategies and tumor risk and support them along their As a national leader in the immunology,” Dr. Mittendorf journey. development of immunotherapy said. The robust platform includes for breast cancer, Dr. Mittendorf laboratory studies, correlative Robust Research has been the principal investigator studies, clinical trials, patient- Platform on numerous trials investigating reported outcome studies and cancer vaccines, including the phase artificial intelligence predictive “We aim to perform high quality III PRESENT trial study of a HER2- modeling. research that asks the right questions targeted vaccine, a study evaluating and moves the field forward,” Dr. vaccination in combination with “In the Clinical Oncology Quality Mittendorf, director of the Breast trastuzumab; and most recently, Database (COQD), we capture data Immuno-Oncology Program and co- the phase III IMpassion031 trial on the diagnosis, treatment and long- director of the Breast Cancer Clinical that showed a benefit of adding term outcomes of all patients that we Research Program at Dana-Farber/ immune checkpoint blockade to operate on as Brigham surgeons,” chemotherapy in the presurgical Dr. Mittendorf said. Established in Brigham and Women's Cancer setting. January 2016, the COQD currently Center, said. “We believe in using includes data for nearly 8,000 patients clinical observations to drive our “Our research program is aimed at and is a tremendous resource for driving clinical innovation focused 30 BWH DOS

Patient-Centered Focus Putting the focus of surgical care on the patientʼs goals for treatment and Dr. Pusic, chief of Plastic and the patient’s experience after surgery Reconstructive Surgery, is an has long been at the core of Dr. Pusic’s internationally renowned innovator practice. A leader in the area of PROs and and leader in patient-reported outcomes surgical experience, Dr. Pusic launched (PROs) and patient satisfaction in surgery. the Patient-Reported Outcomes, Value With dual training in outcomes research & Experience (PROVE) Center at the and surgery, she leads a team of experts Brigham in 2018. She is also principal in psychometrics, quality of life and social investigator of a study funded by the science methods to develop, validate and Patient-Centered Outcomes Research use new quantitative measures to assess Institute (PCORI) that examines how patient outcomes. electronic patient reporting of symptoms may improve surgical care. “Patient-reported outcomes are those outcomes that only patients can know The patient-reported outcomes measure and tell us about,” Dr. Pusic said. “They (PROM) that Dr. Pusic developed for include things like quality of life, breast surgery, the BREAST-Q, has been body image, physical function and the widely adopted for research and clinical experience of care. These are things that care, translated into 40 languages and matter a great deal to our patients.” used as the basis for development of other Breast Surgery Research Program Collaborative investigation across the continuum of care to set new standards for evaluation and treatment of benign and malignant breast disease answering research questions. Prevention Patient- Tailored Tumor “Perhaps most importantly, it and Early Centered Local-Regional Immunology allows us to review our clinical Disease Outcomes experience in order to inform Therapeutic treatment recommendations, as Strategies well as identify areas for research that will positively impact our QUALITY & VALUE | TRAINING & EDUCATION | BIOSPECIMEN COLLECTION breast cancer patients,” Dr. Mittendorf explained. Robust Research Platform The research program LABORATORY STUDIES also maintains an extensive biospecimen collection effort that Tumor biology and immunologic response mechanisms is essential for performing cutting edge research that requires fresh CORRELATIVE STUDIES tumor tissue. All patients operated on at Brigham Heath are asked to Linking tumor types to clinical outcomes consent to specimen collection that allows their breast tissue/tumors CLINICAL TRIALS to be banked and used for research purposes. Assessing existing and emerging therapies PATIENT-REPORTED OUTCOMES STUDIES Validating new clinical care models and documenting survivorship issues ARTIFICIAL INTELLIGENCE PREDICTIVE MODELING Improving risk assessment and treatment guidelines BWH DOS 31

outcome measures in surgery. Next surgery and radiation oncology,” Dr. junior colleagues. We all came here up— the imPROVE Breast Cancer Pusic explained. “The coordination after developing our early careers Care app for patients to record and among all these elements of care here elsewhere, where we learned a follow quality-of-life measures in real is phenomenal.” tremendous amount about how to time on a smartphone. develop an academic career,” Dr. Shaping the Future Mittendorf said. “Working together “Patient-reported outcomes data of Breast Surgical mentoring junior faculty is one are essential whenever the goal of a Oncology important part of our synergy. Our health care intervention is to make shared interests and goals allow us to a patient feel or function better,” Dr. The Breast Surgical Oncology co-mentor and develop these young Pusic explained. “By understanding Fellowship Program at the Brigham clinician-researchers in our vision these outcomes, we can better tailor is among the most competitive and for the future of cancer care and care to individual patients and better sought-after programs of its kind research.” address their needs.” in the country, receiving nearly 100 applications for just two positions “Working with some of the best “Our patient-centered focus gives each year. and brightest young breast surgical us the opportunity to integrate oncologists and expanding the PROMs into every step of the breast “We enjoy creating a supportive patient-centeredness of breast cancer journey,” Dr. Pusic said. environment to mentor these surgery care is exciting,” Dr. Pusic This patient-centered care model trainees,” Dr. King said. “I enjoy said. “We are three female leaders is made possible with the support working with fellows to address shaping a breast cancer care program of physician assistants, nurses clinically relevant research questions around the values of compassion, and nurse practitioners, patient that can be asked and answered collaboration, nurturing and navigators, social workers, and within their one-year fellowship. mentoring.” exercise and nutrition specialists. It is particularly rewarding for our “You can’t get big transformative fellows to have success presenting “We believe that we should learn changes off the ground if you don’t their research at national meetings.” something from every patient that have a great team,” Dr. Pusic said. “We also enjoy mentoring our we care for,” Dr. King said. “We are always looking to move the field “On their breast cancer journey, forward to give back to the next patients want great oncology care, as generation of patients.”  well as great care in surgery, plastic 32 BWH DOS

BREAST SURGERY AND BREAST PLASTIC AND RECONSTRUCTIVE SURGERY by the numbers CLINICAL OPER ATIONS BREAST SURGERY 13 2 8 5 3 BREAST PLASTIC breast nurse nurses AND RECONSTRUCTIVE surgeons breast surgical physician practitioners SURGERY oncology fellows assistants 1 9 9 nurse practitioners breast plastic physician surgeons assistants RESEARCH PERSONNEL BREAST SURGERY 6 9 BREAST PLASTIC 5 3 AND RECONSTRUCTIVE clinical research SURGERY clinical research research staff laboratory staff research staff laboratory staff RESEARCH PORTFOLIO $4,15M Federal, foundation, nonprofit and industry including awards from: total costs in current funding •National Cancer Institute (NCI) •Susan G. Komen •American Society of Clinical Oncology (ASCO) •American College of Surgeons (ACS) •Stand Up To Cancer •Agency for Healthcare Research and Quality (AHRQ) •Patient-Centered Outcomes Research Institute (PCORI) P U B L I C AT I O N S 101original research articles published January to December 2019

Education CURRENT RESIDENTS Darshan Vora, MD George Washington University School The Department of Surgery General Surgery of Medicine combines top-notch clinical care with world-class research Program Director: PGY 2 and cutting-edge education to Stephanie Nitzschke, MD provide comprehensive surgical Associate Program Directors: Alexis Antunez, MD training programs. Teaching Jennifer Irani, MD; Matthew Nehs, University of Michigan Medical School tomorrow’s leaders today… MD, PhD; Naomi Shimizu, MD James Fitzgibbon, MD 152 PGY 1 Lewis Katz School of Medicine at Temple interns and residents University CATEGORICAL 37 Kerri McKie, MD fellows Isaac Alty, MD University of Massachusetts Medical School Harvard Medical School 5 Brittany Powell, MD Jake Awtry, MD Stanford Medical School ACGME-accredited Johns Hopkins University School of Medicine surgical residency programs Cullen Roberts, MD Ilaria Caturegli, MD Warren Alpert Medical School of Brown 5 University of Maryland School of Medicine University ACGME-accredited Eliza Hersh, MD Max Riley, MD surgical fellowships Icahn School of Medicine at Mount Sinai Washington University School of Medicine 12 Annabelle Jones, MD Sarabeth Spitzer, MD Renaissance School of Medicine at Stony Stanford Medical School non-ACGME-accredited Brook University surgical fellowships Megan Sulciner, MD Yun Jee Kang, MD University of Minnesota Medical School 34 BWH DOS Harvard Medical School Biqi Zhang, MD Sangki Oak, MD Harvard Medical School University of Pittsburgh School of Medicine PGY 3 Alexander Ordoobadi, MD Harvard Medical School Karan Chhabra, MD University of Michigan Medical School Soelling, Stefanie, MD Emory University School of Medicine Jessica Feliz, MD University of Virginia School of Medicine PRELIMINARY Adam Fields, MD Christian Cerecedo Lopez, MD Icahn School of Medicine at Mount Sinai Universidad Anáhuac Facultad de Ciencias de la Salud, Mexico Katherine He, MD University of Michigan Medical School Chin Fung [Kelvin] Kan, MD University of Queensland Faculty Patrick Heindel, MD of Medicine, Australia Keck School of Medicine of USC Martin Kauke-Navarro, MD Sameer Hirji, MD Universität zu Köln Medizinische Fakultät, Johns Hopkins University School of Medicine Germany Eva Rouanet, MD Joseph Phalen, MD University of Massachusetts Medical School Boston University School of Medicine Matthew Vivero, MD Ishan Sinha, MD Columbia University Vagelos College Warren Alpert Medical School of Brown of Physicians and Surgeons University Christine Wu, MD Sameer Singhal, MD University of Michigan Medical School George Washington University School of Medicine

PGY 4 James Etheridge, MD Elizabeth Lilley, MD Eastern Virginia Medical School Palliative Care Fellowship, Massachusetts Jamie Knell, MD General Hospital UC San Diego School of Medicine Frances Hu, MD Emory University School of Medicine Rebecca Scully, MD Pamela Lu, MD Vascular Surgery Fellowship, Brigham and University of Massachusetts Medical School Lenka Ilcisin, MD Women’s Hospital Harvard Medical School Arin Madenci, MD James Senturk, MD, PhD University of Michigan Medical School Joshua Jolissaint, MD Minimally Invasive Surgery Fellowship, University of Virginia School of Medicine Mount Sinai Hospital David Mahvi, MD University of Wisconsin School of Medicine Abby Larson, MD Kristin Sonderman, MD, MPH and Public Health Johns Hopkins University School of Medicine Surgical Critical Care Fellowship, R Adams Cowley Shock Trauma Center/University of Danny Mou, MD James Luo, MD Maryland Medical Center Emory University School of Medicine University of Chicago Pritzker School of Medicine Russell Witt, MD William Phillips, MD Hepatobiliary Surgery Fellowship, MD Rush University Medical College Pooja Neiman, MD Anderson Cancer Center David Geffen School of Medicine at UCLA Rowza Rumma, MD Cardiothoracic Surgery Stanford Medical School Paige Newell, MD Integrated (I-6) Program Lewis Katz School of Medicine at Temple Paul Salem, MD University Program Director: Mayo Clinic Alix School of Medicine Michael T. Jaklitsch, MD Laura Piechura, MD PGY 5 Stanford Medical School PGY 1 Bryan Dieffenbach, MD Jason Pradarelli, MD Thais Faggion Vinholo, MD UC San Diego School of Medicine University of Michigan Medical School Yale School of Medicine Anthony Haddad, MD Mehida Rojas-Alexandre, MD John Finnigan, Jr., MD American University of Beirut Faculty Yale School of Medicine Icahn School of Medicine at Mount Sinai of Medicine Lily Saadat, MD PGY 2 Jonathan Hills-Dunlap, MD Northwestern University Feinberg School Stanford Medical School of Medicine Patrick Gedeon, MD Duke University School of Medicine George Li, MD Vanessa Welten, MD Duke University School of Medicine Northwestern University Feinberg School Andreas Habertheuer, MD of Medicine Medical University of Vienna, Austria Heather Lyu, MD Johns Hopkins University School of Medicine Elizabeth Yates, MD PGY 3 University of Michigan Medical School Alessandra Moore, MD Sue Wang, MD University of Massachusetts Medical School Bixiao Zhao, MD UCSF School of Medicine Yale School of Medicine Linda Pak, MD Hoda Javadikasgari, MD University of Michigan Medical School 2020 GRADUATES Tehran University of Medical Sciences, Iran Nidhi Udyavar, MD Alexandra Columbus, MD PGY 4 George Washington University School Minimally Invasive Surgery Fellowship, Lahey of Medicine and Health Sciences Hospital & Medical Center Farhang Yazdchi, MD Shahid Beheshti University of Medical RESEARCH Gillian Fell, MD Sciences, Iran Pediatric Surgery Fellowship, Children’s Rachel Atkinson, MD Hospital LA Yifan Zheng, MD Geisel School of Medicine at Dartmouth Boston University School of Medicine David Harris, MD Sourav Bose, MD Minimally Invasive Surgery Fellowship, Perelman School of Medicine at the Brigham and Women’s Hospital University of Pennsylvania Samuel Enumah, MD Johns Hopkins University School of Medicine BWH DOS 35

RESEARCH PGY 3 2020 GRADUATES Ariana Jones, MD Ciersten Burks, MD Alessandra Colaianni, MD UCSF School of Medicine Indiana University School of Medicine Head and Neck Oncologic and Reconstructive Surgery Fellowship, Vanderbilt Morgan Harloff, MD Lauren Miller, MD University Kaohsiung Medical University, Taiwan Perelman School of Medicine at the University of Pennsylvania Allen Feng, MD Kathleen Weiss, MD Head & Neck Oncologic Surgery and University of Miami Miller School of Medicine Tara Mokhtari, MD Microvascular Reconstruction Fellowship, Stanford Medical School University of Michigan Otolaryngology Alan Workman, MD Natalie Justicz, MD Program Director, Perelman School of Medicine at the Facial Plastic and Reconstructive Surgery Harvard Otolaryngology Residency University of Pennsylvania Fellowship, University of Michigan Program: Stacey T. Gray, MD Assistant Program Director: Vinay Rathi, MD Anuraag Parikh, MD Kevin S. Emerick, MD Yale School of Medicine Head and Neck Microvascular Fellowship, Brigham Site Director: Ohio State University Alice Z. Maxfield, MD PGY 4 PGY 1 Alisa Yamasaki, MD Eric Barbarite, MD General Otolaryngology Private Practice, Riu Han Liu, MD University of Miami Miller School of Medicine Somerset, NJ Johns Hopkins University School of Medicine Adeeb Derakhshan, MD Oral Medicine Margaret Mitchell, MD Cleveland Clinic Lerner College of Medicine Vanderbilt University School of Medicine of Case Western Reserve University Program Director, Oral Medicine Residency Program: Nathaniel Danielle Reny, MD Suresh Mohan, MD Treister, DMD, DDMSc Perelman School of Medicine at the Warren Alpert Medical School of Brown University of Pennsylvania University PGY 1 Isaac Wasserman, MD Krupa Patel, MD Brittany Klein, DDS Icahn School of Medicine at Mount Sinai Weill Cornell Graduate School of Medical University of North Carolina Adams School Sciences of Dentistry Lucy Xu, MD University of Chicago Pritzker School Tiffany Wang, MD PGY 2 of Medicine Keck School of Medicine of USC Prazwala Chirravur, BDS PGY 2 PGY 5 India (certificate program) Ryan Bartholomew, MD Nicholas Abt, MD Malak Al-Hadlaq, BDS Harvard Medical School Johns Hopkins University School of Medicine Saudi Arabia (certificate and DMSc program) Elliana DeVore (Kirsh), MD Jenny Chen, MD PGY 3 Harvard Medical School Harvard Medical School Amal Bajonaid, BDS Krish Suresh, MD Shekhar Gadkaree, MD Saudi Arabia (certificate and MMSc Northwestern University Feinberg School Johns Hopkins University School of Medicine program) of Medicine Vivek Kanumuri, MD Yuanming Xu, DDS Michael Wu, MD Rutgers Robert Wood Johnson Medical China (certificate and MMSc program) Harvard Medical School School Rossella Intini, DDS Roy Xiao, MD Ashley Miller, MD Italy (certificate program) Case Western Reserve University School University of Michigan Medical School of Medicine Shaiba Sandhu, DDS RESEARCH UCSF School of Dentistry (certificate program) Christopher McHugh, MD, PhD Wayne State University School of Medicine Phoebe Kuo Yu, MD Yale School of Medicine 36 BWH DOS

2020 GRADUATE Frankie Wong, MD Ashleigh Francis, MD David Geffen School of Medicine at UCLA Microsurgery Fellowship, MD Anderson Nancy Wilson, DMD Cancer Center Faculty, James B. Edwards College of Dental PGY 5 Medicine at the Medical University of South Mark Greyson, MD Carolina Timothy Irwin, MD Hand Fellowship, UCLA Pennsylvania State University College of Medicine David Mattos, MD Private Practice, Long Island Plastic Surgical Plastic Surgery Dylan Perry, MD Group University of Massachusetts Medical School Program Director, Harvard Plastic Erin Taylor, MD Surgery Residency Program: Arman Serebrakian, MD, MS Microsurgery Fellowship, Memorial Sloan Kyle Eberlin, MD Lewis Katz School of Medicine at Temple Kettering Cancer Center Associate Program Director: University Lydia Helliwell, MD Urology CHIEF RESIDENTS INTEGRATED PROGRAM Program Director: Lisa Gfrerer, MD, PhD George Haleblian, MD PGY 1 Medical University of Vienna, Austria PGY 1 Charles Hwang, MD Brent Pickrell, MD University of Michigan Medical School Baylor College of Medicine Yefri Baez, MD Harvard Medical School Ian McCulloch, MD Jacob Rinkinen, MD West Virginia University School of Medicine University of Michigan Medical School Vincent D’Andrea, MD Zucker School of Medicine at Ricardo Ortiz, MD INDEPENDENT PROGRAM Hofstra/Northwell Harvard Medical School JUNIOR RESIDENTS Kendrick Yim, MD PGY 2 UC San Diego School of Medicine Ashley Ehret, MD Brittany Caruso, MD Rutgers Robert Wood Johnson Medical PGY 2 Lewis Katz School of Medicine at Temple School University Brittany Berk, MD Vishwanath Chegireddy, MD University of Massachusetts Medical School Seth Fruge, MD Morehouse School of Medicine Louisiana State University School of Medicine Catherine Gu, MD SENIOR RESIDENTS Perelman School of Medicine at University Kimberly Khouri, MD of Pennsylvania New York University Grossman School Jason Gardenier, MD, PGY 6 of Medicine University of Virginia School of Medicine Marie Valovska, MD Geisel School of Medicine at Dartmouth PGY 3 Silviu Diaconu, MD, PGY 6 Northwestern University Feinberg School PGY 3 Olivia Abbate, MD of Medicine Georgetown University School of Medicine Tracy Han, MD CHIEF RESIDENTS Duke University School of Medicine Sarah Karinja, MD Columbia University Vagelos College Mario Aycart, MD, PGY 7 Kevin Melnick, MD of Physicians and Surgeons Tufts University School of Medicine Emory University School of Medicine Eric Wenzinger, MD Ravi Sood, MD, PGY 7 Venkat Ramakrishnan, MD Medical University of South Carolina University of Chicago Pritzker School University of Louisville School of Medicine of Medicine PGY 4 PGY 4 2020 GRADUATES Jason Clain, MD Erica Ditkoff, MD Tufts University School of Medicine KC Collins, MD Columbia University Vagelos College Academic Practice, Baystate Medical Center of Physicians and Surgeons Brittany Vieira, MD Northwestern University Feinberg School Joani Christensen, MD of Medicine Microsurgery Fellowship, MD Anderson Cancer Center BWH DOS 37

Gricelda Gomez, MD Adult Cardiac Cardiothoracic Harvard Medical School Surgery Fellowship Surgery Fellowship Stephen Reese, MD Program Director: Program Director: Boston University School of Medicine Tsuyoshi Kaneko, MD Michael T. Jaklitsch, MD PGY 5 Chikashi Nakai, MD PGY 6 Wakayama Medical University, Japan Alexandra J Berger, MD Kryston Boyer, DO Warren Alpert Medical School of Brown 2020 GRADUATE Oklahoma State University Center for Health University Sciences Yuji Kawano, MD Manuel Ozambela, MD Robotics Fellowship, Emory University Darren Bryan, MD Harvard Medical School University of Rochester School of Medicine Advanced Laparoscopic and Dentistry Julie Szymaniak, MD Fellowship Rutgers Robert Wood Johnson Medical Paul Feingold, MD School Program Director: Emory University School of Medicine Ali Tavakkoli, MD 2020 GRADUATES John Kuckelman, DO David Harris, MD Des Moines University College of Medicine Hyo Sang Chiang, MD University of Virginia School of Medicine Urologist, Kaiser Permanente, Colorado Michael Lee, MD 2020 GRADUATE University of Pittsburgh School of Medicine Alexander Cole, MD Urologic Oncology Fellowship, Brigham Colston Edgerton, MD PGY 7 and Women’s Hospital & University College Faculty, Medical University of South Carolina London University Medical Center Marko Boskovski, MD Yale School of Medicine Jeffrey Howard, MD Breast Surgery Fellowship Urologic Oncology Fellowship, UT Anthony Cipriano, MD Southwestern Medical Center Program Director: Lewis Katz School of Medicine at Temple Tari King, MD University Valary Raup, MD Andrology & Prosthetic Urology Fellowship, Halley Vora, MD Mia DeBarros, MD Columbia University Lewis Katz School of Medicine at Temple Boston University School of Medicine University CURRENT FELLOWS Julius Ejiofor, MD Meghan Garstkam, MD UT Southwestern Medical Center Acute Care Tulane University School of Medicine Surgery Fellowship Desiree Steimer, MD 2020 GRADUATES University of Kentucky College of Medicine Program Director: Reza Askari, MD Olga Kantor, MD, MS 2020 GRADUATES Faculty, Brigham and Women’s Hospital Allison Brown, MD Kareem Bedeir, MD University of Wisconsin School of Medicine Alison Laws, MD Cardiac Surgeon, Cardio-Thoracic & and Public Health Faculty, Brigham and Women’s Hospital Vascular Surgical Associates, Mobile, AL 2020 GRADUATE Hassan Khalil, MD Faculty, Brigham and Women’s Hospital Mehreen Kisat, MD Faculty, University of Wisconsin Hospital and Andrew Papoy, MD Clinics Cardiac Surgeon, University of Alabama at Birmingham Sunu Philip, MD Thoracic Surgeon, Pierce Street Surgery Center, Sioux City, IA 38 BWH DOS

Cardiothoracic 2020 GRADUATE Oral Oncology and Oral Surgery Transplant Medicine Fellowship Fellowship Humbo Shim, MD Cardiothoracic Surgery Transplant Program Director: Program Director: Fellowship, Brigham and Women’s Hospital Piamkamon Vacharotayangul, DDS, PhD Antonio Coppolino, MD 2020 GRADUATE Hunbo Shim, MD General Thoracic Hanyang University College of Medicine, Surgery Fellowship Moaiad Salous, DMD Korea OMFS Intern, Lincoln Center, New York, NY Program Director: 2020 GRADUATE Michael T. Jaklitsch, MD Surgical Critical Care Fellowship Mohamed Keshk, MD Jessica Della Valle, MD Staff Surgeon, Brigham and Women’s University of Florida College of Medicine Program Director: Hospital Reza Askari, MD Colorectal Surgery Melanie Lighter, MD Mohammad “Reza” Afrasiabi, MD Fellowship St. George’s University School of Medicine Creighton University School of Medicine Program Director: Jorge Castro, MD Laura Hyde, MD Nelya Melnitchouk, MD, MSc University of Cartagena School of Medicine UCSF School of Medicine Robert Malizia, MD 2020 GRADUATES Renaldo Williams, MD University of Buffalo Jacobs School of University of Mississippi School of Medicine Medicine and Biomedical Sciences Mayrim Rios Perez, MD 2020 GRADUATES 2020 GRADUATE Matthew Pommerening, MD Faculty, Brigham and Women’s Hospital Allison Brown, MD Peter Najjar, MD Acute Care Surgery Fellowship, Brigham Assistant Professor of Surgery, Johns Hopkins Jillian Sinopoli, MD and Women’s Hospital University Thoracic Attending, Case Western Reserve University School of Medicine Choyin “Yvonne” Chung, MD Vascular Surgery Fellowship, Saint Louis Endocrine Surgery Minimally Invasive Thoracic University Fellowship Surgery Fellowship Alfredo Cordova, MD Program Director: Program Director: Assistant Professor of Surgery, Ohio State Matthew A. Nehs, MD Jon O. Wee, MD University Rajshri Gartland, MD Negar Ahmadi, MD Laura Hansen, MD Vanderbilt University School of Medicine University of Toronto Faculty of Medicine Minimally Invasive Surgery Fellowship, Hofstra/Northwell 2020 GRADUATE Kostastinos Poulikidis, MD New York Medical College Sean Wrenn, MD Assistant Professor of Surgery, Rush Medical Center 2020 GRADUATES Endovascular Cardiac John S. Young, MD Surgery Fellowship Faculty, Brigham and Women’s Hospital Program Director: Ealaf Shemmeri, MD Thoracic Surgery Residency, University Tsuyoshi Kaneko, MD of Buffalo Morgan Harloff, MD Kaohsiung Medical University, Taiwan BWH DOS 39

Surgical Oncology Fellowship Urological Oncology Vascular Surgery Fellowship Fellowship Program Director: Program Director: Chandrajit P. Raut, MD, MSc Program Director: Matthew Menard, MD Steven L. Chang, MD, MS Thinzar Lwin, MD Andrew Servais, MD New York Medical College Eugene Cone, MD Tufts University School of Medicine Warren Alpert Medical School of Brown Winta Mehtsun, MD University Rebecca Scully, MD University of Virginia School of Medicine Geisel School of Medicine at Dartmouth Alexander Cole, MD 2020 GRADUATE Johns Hopkins University School of Medicine Andrew Soo Hoo, MD Wayne State University School of Medicine George Molina, MD 2020 GRADUATES Faculty, Brigham and Women’s Hospital 2020 GRADUATES Melissa Huynh, MD Attending Physician, Schulich School of Gaurav Sharma, MD Medicine & Dentistry at Western University, Attending Surgeon, Kaiser Permanente, Ontario California Alice Yu, MD Jillian Walsh, MD Attending Physician, Moffitt Cancer Center Attending Surgeon, Capital Health, New Jersey Visiting Professors Stephanie Nitzschke, MD, Named Program Director of the Brigham David J. Sugarbaker General Surgery Residency Program Lectureship in Thoracic Surgery Dr. Nitzschke is an acute care surgeon, Gail Darling, MD, FRCSC, FACS trauma surgeon and surgical intensivist University of Toronto at Brigham and Women’s Hospital and an instructor in surgery at Harvard Medical Joseph E. Murray Visiting School. She is a graduate of Loyola University Professor in Transplant Stritch School of Medicine and completed Surgery a general surgery residency at INOVA Donna L. Farber, PhD Fairfax Hospital. She also completed a burn Columbia University Medical Center surgery fellowship at the U.S. Army Institute of Surgical Research and a trauma and Lawrence and Judith Schlager critical care fellowship at the University of Family Lecturer in Surgical Pennsylvania. She joined the trauma and Oncology critical faculty in 2014 and has been the Jennifer Tseng, MD, MPH medical director of the Brigham Burn Center Boston Medical Center since 2017. Nina S. Braunwald Visiting Dr. Nitzschke is an active participant in Lecturer in Surgery resident and medical student education. Her Jennifer Romano, MD research interests include clinical outcomes University of Michigan Medical for burn and trauma patients. She has School authored over 20 peer-reviewed manuscripts and chapters and presented 20 surgical 40 BWH DOS care abstracts and lectures regionally and nationally. 

Research Brigham Health is an international powerhouse in biomedical research dedicated to pioneering discoveries that will translate into new prediction methods, treatments, and cures for the world’s most devastating and complex diseases. 454 188 389 research funds active grants & contracts active protocols 63 56 research fellows active clinical trials $40,501,132 research spending SELECTED GRANTS Adaptive immune regulation of traumatic injury PI • James Lederer, PhD Defining mechanisms of immunotherapy resistance in Sponsor • National Institutes of Health (NIH) head and neck squamous cell carcinomas Grant Amount • $ 2,073,180 PI • Ravindra Uppaluri, MD, PhD Sponsor • National Institutes of Health (NIH) SELECTED CLINICAL TRIALS Grant Amount • $ 4,259,203 CTA • Genetic testing for all breast cancer patients (GET Understanding and improving surgical decision-making FACTS) for persons living with dementia, their family caregivers PI • Anna Weiss, MD and their providers: A mixed methods study Sponsor • Myriad Genetics, Inc. PI • Joel Weissman, PhD Sponsor • National Institute on Aging (NIH-NIA) MDIC Work Order • AltaValve early feasibility study Grant Amount • $ 4,172,072 protocol PI • Tsuyoshi Kaneko, MD Senescent cells drive mt-DNA accumulation and Sponsor • 4C Medical Technologies, Inc. inflamm-aging PI • Stefan G. Tullius, MD, PhD CTA • Post-market retrospective study of the Renú soft Sponsor • National Institute on Aging (NIH-NIA) tissue (volumizing) implant (Renú Voice) in the treatment Grant Amount • $ 2,554,955 of vocal fold medialization and vocal fold insufficiency PI • Thomas Carroll, MD Prevalence effects in visual research: Theoretical and Sponsor • Cytophil, Inc. practical implications PI • Jeremy M. Wolfe, PhD BWH DOS 41 Sponsor • National Eye Institute (NIH-NEI) Grant Amount • $ 1,790,000

Stefan G. Tullius, MD, PhD Awarded $2.5M National Institutes of Health Grant Dr. Tullius was awarded a National immunogenicity. With aging, senescent cells accumulate, producing Institutes of Health (NIH) grant increasing amounts of inflammatory products. for his study, “Senescent cells drive mt-DNA accumulation and This grant will delineate specific immune responses when inflamm-aging.” transplanting older organs. Dr. Tullius and his group will test if the depletion of senescent cells through senolytics will improve The sharp discrepancy transplant outcomes and modify immune responses. The between demand and supply proposal will also test if senescent cells will be transferred in organ of organs causes high mortality transplants and if those senescent cells will impact aging. As donor and morbidity rates in waitlisted and recipient ages may vary substantially, it is also possible that patients. Organ transplantation aging processes in transplant recipients may be either accelerated is hampered by a limited supply or that the transplantation of a younger organ will slow aging. The of organs, with many patients supported research may help to increase the availability of organs waiting for numerous years for transplants, delineate organ-age specific immune responses and numerous patients dying before getting a transplant. The and determine the fate of senescent cells transferred with organ aging population is also on the rise, and although organs from transplantation. Optimizing the utilization and outcomes of older older donors are available, they are frequently not considered or transplanted organs is also expected to reduce mortality and discarded with concerns of compromised function and augmented morbidity rates of waitlisted patients with end-stage organ failure.  Joel S. Weissman, PhD Awarded $4.4M National Institutes of Health Grant Dr. Weissman was awarded a persons living with dementia, challenges of surgical decision- understand the landscape National Institutes of Health their family caregivers and making in clinical settings. of surgical decision-making (NIH) grant for his study, their providers: A mixed The study focuses on surgery among PLWD and providers “Understanding and improving methods study.” because it is common among prior to assessing surgical surgical decision-making for elderly PLWD, represents outcomes among these Surgical decision-making is a critical inflection point in patients. Results will provide challenging for persons living quality of life and therefore, critical data to inform training with dementia (PLWD) due to is a fraught process for all on how best to care for PLWD limited longitudinal data on involved. facing surgery and support outcomes, a patientʼs limited policy decisions designed to ability to fully participate in Results of this study will improve patient-centered care. the discussion and an absence support key advancements in Surgeons and other providers, of evidence-based guidelines. Alzheimerʼs Disease Related along with patients and their The aim of this study is to Dementias (ADRD) research caregivers, will be able to use understand the epidemiology by focusing on under-studied these data to improve surgical of surgery for PLWD, as areas of surgical decision- decision-making to align care well as patient, caregiver, making by key stakeholders. with patient values.  and provider practices and Currently, there is a need to 42 BWH DOS

Jeremy Wolfe, PhD Awarded $1.8M National Institutes of Health Grant Dr. Wolfe was awarded a grant have undesirable effects. Most “Dual-Threshold” model that internal, mental representation from the National Institutes of notably, miss (false negative) better captures the important of the search target (or targets). Health (NIH) and the National errors are markedly elevated at aspects of the prevalence Project 2 is concerned with the Eye Institute (NEI) for the study, low prevalence. This is a clear effect data by proposing two impact of prevalence on these “Prevalence effects in visual problem if the purpose of the effects of low prevalence: (1) “target templates.” Advances research: Theoretical and search is to detect something the conservative shift in the in artificial intelligence (notably practical implications.” rare but important like cancer criterion for deciding if an deep learning) are producing or a terrorist threat. Previous attended item is a target and tools to assist expert searchers. Low prevalence searches work has documented this (2) a lowering of the “quitting However, once deployed, these form an important and pattern of increased miss threshold.” The quitting AI tools have been less effective problematic class of visual errors in several expert threshold determines when than theory predicts. Project 3 search tasks. These are tasks domains, including cytology observers end a search. tests the hypothesis that part where the search target is rare. (cervical cancer screening), Quitting too soon also of the problem is another side Many socially important tasks airport baggage screening increases the chance that the effect of low prevalence, and like airport security or cancer and breast cancer screening. observer will miss a target. the project tests a potential screening are low prevalence False alarm (false positive) intervention. Finally, clinicians tasks. Previous work, much error rates typically decline Prevalence effects have searching for one type of target of it from Dr. Wolfeʼs lab, has at low prevalence, moving in been studied in experimental (e.g., pneumonia) are supposed shown that low prevalence can the opposite direction from isolation from other aspects to report signs of other miss errors. This indicates a of search. However, in tasks possible problems (e.g., lung shift in the observer’s decision like breast cancer screening, cancer). Project 4 probes the criterion. At low prevalence, other factors interact with role of prevalence in the failure observers become more prevalence. The four projects to report such “incidental reluctant to call something a in the present proposal findings.” Again, several target. Several studies have each investigate one of interventions are tested. shown that this “conservative” these interactions. Project 1 This is “use-inspired, basic criterion shift is not adequate examines the relationship of research” whose results will to explain the entire prevalence prevalence to the “vigilance provide guidance for experts effect. Dr. Wolfe and Dr. decrements” that are seen as performing socially important VanWert (2010) developed a time elapses in a task. In search, low prevalence tasks.  observers must maintain an Ravindra Uppaluri, MD, PhD Awarded $4.3M Cancer Moonshot Grant Dr. Uppaluri, chief of the to accelerate cancer research and aims to make more therapies Division of Otolaryngology- available to more patients, while also improving our ability to Head and Neck Surgery in the prevent cancer and detect it at an early stage. Department of Surgery and chief of Head and Neck Surgical Dr. Uppaluri will serve as principal investigator on this project Oncology at Dana-Farber and alongside David Barbie, MD, and Robert Haddad, MD, both from Brigham and Women’s Cancer Dana-Farber Cancer Institute. Co-Investigators include James Center, received a U01 Cancer Lederer, PhD, and Ann Marie Egloff, PhD, MPH, both from the Moonshot grant from the Brigham Department of Surgery; and Robert Manguso, PhD, National Cancer Institute (NCI) from the Broad Institute. The team seeks to understand why and the National Institute of many patients with head and neck cancers display resistance Dental and Craniofacial Research to immunotherapy drugs, with the goal of improving treatment (NIDCR) for his project, “Defining mechanisms of immunotherapy response rates for this patient population. resistance in head and neck squamous cell carcinomas.” An initiative of the NCI, the Cancer Moonshot program seeks The NCI is the federal government’s principal agency for cancer research and training. The mission of the NIDCR is to improve dental, oral and craniofacial health.  BWH DOS 43

CENTER FOR SURGERY AND PUBLIC HEALTH (CSPH) Making surgery safer, more patient-centered, and more accessible in the U.S. and around the world. cancer military and comparative outcomes research effectiveness program on CSPH Research ATIVE METHODS •• patient- Cores FOCUS ON oriented policy global •••••••• • • • • • • • • •••• ••QUALIT & practice surgery (ppopp) • • • QUANTIT PATIENT-CENTERED surgical culture HEALTH CARE THAT IS SAFE, EFFECTIVE, AND EQUITABLE ATIVE METHODS ••••• trauma, surgical health emergency scientists aligning general surgery, & long-term research with outcomes patient priorities (SHARPP) Founded in 2005 as a joint initiative surgical safety checklists, created more accessible in the U.S. and of Brigham and Women’s Hospital, a national agenda for surgical around the world. Harvard Medical School and disparities research and launched the Harvard T.H. Chan School the pioneering work of rising stars In the past months, the COVID-19 of Public Health, the Center for in surgical health services research. pandemic and the health systemʼs Surgery and Public Health (CSPH) They are advancing the science of response has led to new challenges has been at the forefront of public surgical care delivery by studying and exposed old problems within health research of surgical care effectiveness, quality, equity and the U.S. health system. The CSPH delivery within and without value at the population level and has responded with a surgical our nation’s health care system. training the most gifted of a new health services research agenda Utilizing innovative research generation of physician-scientists. for the COVID-19 pandemic, and methodologies grounded in clinical Their efforts are making surgery the centerʼs director, Zara Cooper, reality, the center has developed safer, more patient-centered and MD, MSc, recently joined Annals of Surgery as an associate editor, 44 BWH DOS

NEW FUNDING HIGHLIGHTS Zara Cooper, MD, MSc, Thomas C. Tsai, MD, National Collaborative The overarching goal was awarded $156,000 MPH, was awarded on Gun Violence of the proposal is from the National $337,219 from the Research: The study, to identify ways to Palliative Care Research Massachusetts “Evaluating and improve hospital billing Center (NPCRC) for her Consortium on Pathogen improving the accuracy data efficiently and study, “The trauma dyad: Readiness (MassCPR) of ICD-coded hospital substantially such that Tended to caregivers and the Massachusetts data systems in they can be used for of injured frail elders,” Life Sciences Center estimating the incidence surveillance of nonfatal which involved recruiting (MLSC) for his study, of nonfatal firearm firearm injuries by informal caregivers “Update to the HGHI injuries by intent type,” a intent. Matthew Miller, of older adults who COVID-19 U.S. hospital collaboration of Brigham MD, ScD, MPH, co- have gone through a capacity model: ICU and Womenʼs CSPH director of the Harvard traumatic injury. surge, post-acute care and the Department of Injury Control Research beds and survey of Emergency Medicine; Center, is overall PI and Joel Weissman, mechanical ventilator Northeastern University; Eric Goralnick, MD, MS, PhD, was awarded a supply.” the Harvard Injury is site PI. $4.4 million National Control Research Institutes of Health Molly Jarman, PhD, Program at the Harvard (NIH) R01 grant for the MPH, was awarded T.H. Chan School of study, “Understanding a $606,250 National Public Health; and the and improving surgical Institute on Aging (NIA) Medical Text Extraction, decision-making for K01 Mentored Research Reasoning, and Mapping persons living with Scientist Development System (MTERMS) lab, dementia, their family Award for the project, led by Li Zhou, MD, PhD, caregivers and their “Health impacts of was awarded a two-year providers: A mixed prehospital pain grant by the National methods study.” management for injured Collaborative on Gun older adults.” Violence Research. 6 207 13 publications published active fellows fellows graduated leading a focus on the promotion of accessible and more affordable Military Health System to provide equity and social justice in surgical health systems for all patients. the best, most effective care for care and workforce. The CSPH continues to focus on military service members and their research that matters—from the families, while also providing The CSPH is continuing to expand role health care practitioners can significant insight into how to create its role as an intellectual home for play in preventing and mitigating an equitable health system. The surgical health services research firearm injury, to untangling how CSPH is helping develop consensus at Brigham and Women’s Hospital. dementia impacts a patient’s ability on what “serious illness” looks The center’s growing cohort of up- to communicate palliative and like in the preoperative context, by and-coming researchers includes surgical care goals. The center’s examining access to surgical care in surgeons and PhD researchers, continuing partnership with the Chiapas, Mexico, and what “quality” who are looking to challenge our Uniformed Services University of and “access” mean in pursuit of assumptions in the pursuit of the Health Sciences is assisting the eliminating disparities.  creating safer, more effective, more BWH DOS 45

To leverage leading-edge techniques to transform the collection, analysis and feedback of patient-reported outcomes and experiences at Mass General Brigham and around the world. YEAR AT A GLANCE through iterative cycles of feedback from and challenge to patients, health care patients and key stakeholders. Over the professionals and health care systems alike. EXPANDED their support to eight past 18 months, the team has worked Wound impact on patients varies greatly members of Brigham Surgery faculty: closely with their IT vendor (ADK Group) and in terms of recovery and return to usual Two research faculty, six residents, a key stakeholders to refine the content and activities and health-related quality of life postdoctoral research fellow, seven build the platform. They have held seven (HRQOL). The WOUND-Q is a new patient- students and nine visiting scholars. multidisciplinary stakeholder meetings reported outcome measure developed with 24 experts in the field of breast by the Breast Surgery team to assess PUBLISHED 53 papers in journals, cancer care (three patient advocates, six wound characteristics, health-related including Annals of Surgery, The Lancet breast and plastic surgeons, four medical quality of life, and experience of care and Oncology, Plastic and Reconstructive Surgery oncologists, three radiation oncologists, treatment in patients with all types of and Quality of Life Research. one anesthesiologist, two nurses and chronic wounds in any anatomic location. five resident researchers); three Harvard Scale content was developed and refined LAUNCHED the imPROVE Breast Cancer Business School affiliates, with expertise in through 60 qualitative and 20 cognitive Care app, developed in collaboration with value-based health care; and four product interviews with patients and feedback the Division of Breast Surgery, Dana-Farber developers/designers. Individual patient from 21 experts. Field-test data provided Oncology and patient advocates. interviews with 24 patients and two focus by over 1,000 participants from four groups with 12 members of the DFCI Patient countries (the U.S., Canada, Denmark and COMPLETED the development and Family Advisory Council (PFAC) have also the Netherlands) was used to finalize the international validation of two new patient- been completed. Findings from these WOUND-Q. Data was analyzed using the reported outcome measures (PROMs): The meetings, interviews and focus groups were Rasch measurement theory (RMT) analysis WOUND-Q for chronic wounds and the used to generate design ideas, including to identify the best subset of items to retain LYMPH-Q for lymphedema patients. the features, functionalities and content in each scale based on a standardized set for the platform. Feedback was obtained of psychometric criteria. The WOUND-Q KEY INITIATIVES in an iterative manner and brought back has since been finalized and will now to the IT developers for refinement of the be made available for distribution. The imPROVE Breast Cancer Care platform. Starting September 2020, they manuscript describing the development of Andrea Pusic, MD, Tari King, MD, and began user testing and implementation of the WOUND-Q is currently in preparation. teams are leading an initiative to develop the patient-facing web application within The team plans to publish additional clinical and implement a new electronic platform the breast surgery service at DFCI. They will papers from this dataset. The WOUND-Q called imPROVE Breast Cancer Care. The also continue to build and implement the will be an important tool to improve clinical imPROVE project is being conducted in clinician- and administrative-facing portals care and evaluate new treatments for collaboration with breast cancer care over the coming year. patients with chronic wounds. providers, patients and patient advocates at Brigham and Women’s Hospital and Measuring Outcomes and Experiences Development of a condition-specific Dana-Farber Cancer Institute (DFCI), as well of Chronic Wound Patients: The patient-reported outcome measure as members of Harvard Business School WOUND-Q for patients with upper extremity (HBS) and the International Consortium Each year, millions of individuals require lymphedema: The LYMPH-Q Upper for Health Outcomes Measurement treatment for chronic wounds. Wounds Extremity Module (ICHOM). imPROVE consists of a patient- represent an important health problem Breast cancer treatment is the most facing web application and clinician- and administrative-facing portals developed 46 BWH DOS

common cause of upper extremity from around the world who are aged 18 and specific codes related to eating from lymphedema in Western countries. Risk years or older. Over 2,000 participants the original set of 63 patient interview factors for developing arm lymphedema provided data and analysis. Manuscript transcripts. Scale refinement included include axillary lymph node dissection preparation is currently underway. The cognitive interviews with 17 patients and (ALND), sentinel lymph node biopsy team will also continue to prospectively feedback from 19 experts. To finalize and radiation therapy of the axilla or a survey this patient population over time. the scales, an international field test was combination of these treatments. Arm conducted with patients from Canada, lymphedema is a debilitating diagnosis Measuring Patient-Reported Outcomes Denmark, the Netherlands and the U.S. that may significantly diminish a in Bariatric Surgery: The BODY-Q Data was also obtained through Prolific. patient’s HRQOL due to symptoms (e.g., In collaboration with the Brigham Over 4,000 (2,057 Prolific and 1,947 clinical) swelling, pain, infection) and reduced Health Center for Weight Management participants were enrolled in the field-test arm function. To better understand and Metabolic Surgery, Dr. Pusic, Ali study and the Rasch measurement theory and measure outcomes that matter to Tavakkoli, MD, and team have established (RMT) analysis was used to refine and patients with arm lymphedema, a valid an international collaboration with the finalize the scales. Multiple papers have and reliable patient-reported outcome Netherlands and Denmark to develop been published and are being prepared measure (PROM) was needed. The team and validate new scales that form the from this data. conducted in-depth and semi-structured BODY-Q Eating Module. The BODY-Q is qualitative interviews with women with a patient-reported outcome measure Development and validation of new arm lymphedema following breast cancer published in 2009 that was developed scales to measure outcomes related to treatment to develop items that will form to measure outcomes of bariatric and breast cancer and its treatment the lymphedema scales. Scales were body contouring surgery. The BODY-Q The BREAST-Q is a patient-reported later refined through cognitive interviews Eating Module fills an important gap in the outcome measure (PROM) for breast with patients and clinical experts. existing BODY-Q scales, measuring the surgery patients developed by the Finally, a field test was performed on an following constructs: Expectations from Breast Surgery team that is widely used international sample of 3,222 women in weight loss, eating behavior, eating-related nationally and internationally. Recently, the U.S. (through the Love Research Army) distress, work life and eating-related the BREAST-Q was qualified by the FDA for and Denmark. The Rasch measurement symptoms. Content for these scales was use in regulatory decisions. This year, they theory (RMT) analysis was used to developed from reexamining the general developed additional BREAST-Q scales examine reliability and validity. Manuscript preparation for the study is currently underway for submission to a peer- reviewed journal. Understanding health-related quality of life (HRQOL) and psychological well- being during the COVID-19 pandemic The COVID-19 pandemic has resulted in unprecedented, sudden interruptions or alterations to the general population’s lifestyle, fundamentally altering how Americans live their lives. These sudden changes may impose significant consequences on a person’s overall health-related quality of life (HRQOL) and psychological well-being. This study aims to understand the impact of COVID-19 on self-reported HRQOL and psychological well-being (depression and anxiety) and to identify factors associated with the experiences of stigma. HRQOL and psychological well-being were assessed using the PROMIS Global Health 10 Survey, the Patient Health Questionnaire-9 (PHQ- 9) and the Generalized Anxiety Disorder 7-item (GAD-7) scale. In May 2020, the baseline survey was distributed through Prolific, an online community of members BWH DOS 47

to further expand its use and support success rates, the lack of a validated Alliance U.S. member innovation in reconstructive surgery. patient-reported outcome measure (PROM) sites include 46 Academic that captures important concepts for these Medical Centers and 1.BREAST-Q Sensation Module patients makes it impossible to accurately 72 Community Health In recent years, surgical innovation measure the extent to which these Systems. and the availability of cadaveric nerve operations improve patient quality of life. grafts have offered potential return The objective of this project is to develop Alliance Foundation Trials of breast sensation. To support and validate a PROM specific for face are also underway in seven outcomes research in this area, the team vascularized composite tissue candidates other countries: Australia, developed new scales that form the and recipients. To date, the team has Austria, Canada, France, BREAST-Q Sensation Module. Content conducted a systematic literature review Germany, Italy and Spain. was developed and refined from 36 to identify PROMs that are currently being qualitative and seven cognitive interviews used to measure outcomes in this patient A total of 52 Alliance-led with patients and feedback from 18 population and develop a preliminary therapeutic clinical trials are experts. In collaboration with the Love conceptual framework (manuscript in currently enrolling patients Research Army (formally known as the preparation). They have also performed in- with a range of cancers: GI Army of Women), a field-test study was depth qualitative and cognitive interviews tract, breast, lung, GU tract, performed, and 1,204 members provided with three postoperative patients. brain, leukemia, lymphoma, data to finalize the scales. The new Qualitative interviews were conducted myeloma, endocrine and skin. scales measure breast sensation, quality using a semi-structured interview guide of life impact and breast symptoms. and cognitive interviews involved the Alliance research Development of the BREAST-Q Sensation review of existing scales from the FACE-Q operations team spearheaded Module was funded by The Plastic Head and Neck Cancer and Craniofacial the activation of the Surgery Foundation (The PSF). Modules teams using the think-aloud “Evaluation of SARS-CoV-2 approach. Qualitative and cognitive antibody-containing plasma 2.BREAST-Q Animation Deformity interviews will continue with pre and thErapy” (ESCAPE) trial: “A Scale postoperative patients until saturation of prospective, randomized, Implants have traditionally been concepts is achieved. double-masked, placebo- placed underneath the pectoralis controlled trial of high-titer muscle (subpectoral). This approach Scaling and spreading electronic COVID-19 convalescent to implant placement results in capture of patient-reported outcomes plasma (HT-CCP) for the animation deformity, where the shape using a National Surgical Quality treatment of hospitalized of the reconstructed breast changes Improvement Program (NSQIP) patients with COVID-19 of or distorts when the pectoralis muscle Incorporating the patient’s perspective moderate severity.” contracts and the implant moves. to evaluate surgical quality has yet to be Treatment options to mitigate animation achieved in the U.S. and represents a Alliance research also deformity have advanced to include tremendous unrealized opportunity for continues to be active in areas prepectoral implant placement. To better continuous quality improvement. This is a of biomarker development, understand the impact of animation $1.5M AHRQ R18 grant for which Dr. Pusic cancer prevention, cancer deformity and its treatments, the team will serve as co-PI with Clifford Y. Ko, MD, care delivery research, recently finalized the development of from the American College of Surgeons outcomes research, health the animation deformity scale for the (ACS) and Larissa Temple, MD, from the disparities and symptom BREAST-Q Reconstruction Module. Field- University of Rochester Medical Center. intervention. test data from 651 members of the Love The study aims to scale and spread the Research Army were used to finalize routine, health IT-enabled collection of New Alliance initiatives the scale. patient-reported outcomes (PROs) from in the past year include a ambulatory surgical patients using a working group focusing on Development of a condition-specific well-established national surgical quality rural sites and a Value of patient-reported outcome measure improvement registry program. To date, Cancer Care Working Group. for patients undergoing vascularized over 2,400 patients in nine centers have composite tissue allotransplantation contributed data. Results of this research In 2020 Alliance launched the of the face will accelerate the uptake of using PROs ICAREdata initiative, a project Facial transplant surgery seeks to restore for quality improvement across the U.S., to facilitate clinical research function, as well as improve psychological identify best practices for implementation using the electronic health health and social participation for patients of such a program and explore whether record. who have experienced catastrophic PROs can reliably identify quality injuries. Despite high clinician-reported improvement opportunities.  48 BWH DOS

top docs Boston Magazine’s 2020 “Top Doctors” issue recognized 44 Department of Surgery faculty members this year. Congratulations to the following providers for being recognized as the best in their respective fields: Colon and Rectal Surgery Katherina Calvillo, MD Steven Mentzer, MD Ronald Bleday, MD Thomas Clancy, MD Scott Swanson, MD Christian Corwin, MD Gerard Doherty, MD Jon Wee, MD Joel Goldberg, MD, MPH Margaret Duggan, MD Daniel Wiener, MD Atul Gawande, MD, MPH Otolaryngology Pardon Kenney, MD, MMSc Urology Donald Annino, MD, DMD Tari King, MD Steven Chang, MD, MS Sayeed Malek, MD Adam Kibel, MD Plastic Surgery Faina Nakhlis, MD Michael Malone, MD Matthew Carty, MD Chandrajit Raut, MD, MSc Michael O’Leary, MD, MPH Yoon Chun, MD Esther Rhei, MD Graeme Steele, MD Dennis Orgill, MD, PhD Scott Shikora, MD Bohdan Pomahac, MD Douglas Smink, MD, MPH Vascular Surgery Andrea Pusic, MD Ali Tavakkoli, MD Michael Belkin, MD Christian Sampson, MD Ashley Vernon, MD Edwin Gravereaux, MD Simon Talbot, MD Matthew Menard, MD Thoracic and Cardiac Surgery Charles Ozaki, MD Surgery Raphael Bueno, MD Stanley Ashley, MD Christopher Ducko, MD Monica Bertagnolli, MD Hari Mallidi, MD The following board-certified Brigham Oral Medicine specialists were included in Boston Magazine’s “Top Dentists 2020” list: Nathaniel Treister, DMD, DMSc • Sook-Bin Woo, DMD, MMSc BWH DOS 49

News Donald Annino, MD, was selected for President’s Task Force on Race; and & Notes the William W. Montgomery Award for was named associate editor of Annals Excellence in Teaching by the graduating of Surgery. New Endowed Chairs chief residents from the Harvard M. Blair Marshall, MD Medical School (HMS) Otolaryngology— Laura Dominici, MD, was appointed Michael A. Bell Family Head & Neck Surgery Residency chair of the Dana-Farber/Brigham Distinguished Chair in Program. and Women’s Cancer Center Cancer Healthcare Innovation Committee of the American College of Chandrajit P. Raut, MD, MSc Stanley Ashley, MD, was appointed Surgeons (ACS) Commission on BWH Distinguished Chair in to the American College of Surgeons Cancer (CoC). Surgical Oncology (ACS) Board of Governors; the ACS Robert Riviello, MD, MPH Massachusetts District #2 Committee Atul Gawande, MD, MPH, was Steven C. and Carmella on Applicants; the Massachusetts appointed chairman of the board of R. Kletjian Foundation Physician Health Services (PHS) Clinical Haven, the health care venture founded Distinguished Chair in Global Advisory Committee; and was selected by Amazon, Berkshire Hathaway and Surgery as a member of the ACS Academy of JPMorgan Chase, after two years as Master Surgical Educators. founding CEO. Faculty Promotions Reza Askari, MD, was selected as a Joaquim Havens, MD, was awarded Professor member of the Brigham Quality & Risk the Brigham Murray Simonian Mentor Tari A. King, MD Management (QA/RM) Committee; Award. Associate Professor and received the Outstanding Faculty Robert Riviello, MD, MPH Mentor Award from Harvard Medical Lydia Helliwell, MD, was appointed Assistant Professor School (HMS). associate program director for the Thanh Barbie, MD Harvard Plastic Surgery Combined Jessica Erdmann-Sager, MD Regan Bergmark, MD, was awarded Residency Program. Martin Kathrins, MD the 2020 Brigham and Women’s Suniti Nimbkar, MD Hospital Faculty Career Development Kamal MF Itani, MD, was awarded Hisashi Tsukada, MD, PhD Award. the 2019 Association of VA Surgeons Daniel Wiener, MD Distinguished Service Award. Monica Bertagnolli, MD, was elected 50 BWH DOS to the American Cancer Society Board Molly Jarman, PhD, MPH, was of Directors. selected for participation in the National Institute on Aging Butler-Williams Christopher Burns, MD, was named Scholars Program; was awarded the assistant trauma medical director at James G. Zimmer New Investigator South Shore Hospital; was selected Research Award from the American as a member of the Minimally Invasive Public Health Association (APHA) Aging Surgery and Emerging Technologies and Public Health Section; and was Ad Hoc Task Force of the Eastern awarded the Loan Repayment Program Association for the Surgery of Trauma for Health Disparities Research Award (EAST); was a recipient of the Brigham from the National Institute on Minority 2020 Donald D. Matson Teaching Health and Health Disparities (NIMHD). Award; and was selected as a member of the Military Health System Strategic Tsuyoshi Kaneko, MD, was selected as Partnership American College of a member of the American Association Surgeons (MHSSPACS). for Thoracic Surgery (AATS) Foundation JATS Fellowship Committee; and was Nancy Cho, MD, was nominated chair selected as a member of the American of the Communications Committee for College of Cardiology (ACC) Cardiac the Society of Asian Academic Surgeons Surgery Team Member Section and (SA A S). Leadership Council. Thomas Clancy, MD, was awarded Pardon Kenney, MD, was honored the Nobility in Science Award from the for his 30 years of service as chief National Pancreas Foundation (NPF). of Surgery at Brigham and Women’s Faulkner Hospital with the naming of the Zara Cooper, MD, MSc, was elected surgical service as the “Kenney Service”; chair of the Brigham Equity Advisory and was a visiting professor at Mount Council; was selected as a member of Auburn Hospital. the American College of Surgeons (ACS)

Adam Kibel, MD, was elected secretary Faina Nakhlis, MD, was named Jennifer Shin, MD, SM, was the of the Society of Urologic Oncology associate director of the Dana-Farber invited lecturer for the Robert J. Toohill (SUO); and was the Caulk Visiting Cancer Institute Inflammatory Breast Lectureship at the Medical College Professor at Washington University Cancer Program. of Wisconsin and the Robert Ruben in St. Louis. Lectureship at Albert Einstein College of Stephanie Nitzschke, MD, presented Medicine; and was awarded the Inaugural Sayeed K. Malek, MD, was appointed grand rounds at the University of Outstanding Citizenship Award from the to serve on the New England Organ Massachusetts and Boston MedFlight. Brigham Department of Surgery. Bank Clinical Policy Board of the New England Donor Services (NEDS); was Dennis P. Orgill, MD, PhD, was a Indranil Sinha, MD, joined the editorial appointed to the Cellular Transplantation Plastic Surgery Foundation (PSF) visiting board of Current Regenerative Medicine; Committee of the American Society of professor; was selected program chair of was a visiting assistant professor to Transplant Surgeons (ASTS); was named the American Society of Plastic Surgeons the University of Michigan; was named interim chief of Transplant Surgery (ASPS) Annual Meeting; was appointed to a National Institute on Aging Pepper at Boston Medical Center; and was a the Wound Healing Society (WHS) Board Centers Visiting Scholar to the University visiting professor at hospitals in Xi’an and of Directors; and was appointed to the of Connecticut and the Barshop Institute; Changsha, China. Hidradenitis Suppurativa Foundation and filed a patent for an invention that Board of Directors. prints muscle scaffolds directly onto Hari R. Mallidi, MD, was appointed the injury sites. 2020 cardiac track chair and the section Erika Rangel, MD, MS, was awarded editor for Special Topics for the American the BWH Department of Surgery Junior Doug Smink, MD, MPH, was named Society for Artificial Internal Organs Fellowship in honor of Robert T. Osteen president-elect of the Association of (ASAIO). Award from the Harvard Medical Program Directors in Surgery (APDS); and School Eleanor and Miles Shore Faculty was awarded the Mass General Brigham M. Blair Marshall, MD, was named Development Awards Program (Shore Champion of Education Award. the associate chief of Quality and Safety Program). for the Division of Thoracic Surgery; Ali Tavakkoli, MD, was nominated was named the Michael A. Bell Family Chandrajit P. Raut, MD, MSc, was president-elect of the Massachusetts Distinguished Chair in Healthcare appointed chair of the Society of Surgical Chapter of the American College of Innovation at the Brigham; and was Oncology (SSO) Local Arrangements Surgeons (MCACS). named editor-in-chief of Operative Committee. Techniques in Thoracic and Cardiovascular Stefan G. Tullius, MD, PhD, Surgery. Robert Riviello, MD, MPH, was received the Excellence in Kidney awarded the Inaugural Outstanding Transplantation Award from the Christina Minami, MD, MFA, MS, Citizenship Award from the Brigham National Kidney Foundation (NKF); was awarded the American Society of Department of Surgery; and presented received the Outstanding Achievement Clinical Oncology (ASCO) Endowed Young the keynote address on Innovations Transplantation Science (Basic) Award Investigator Award in Geriatric Oncology; in Global Surgery at the 2019 Harvard from The Transplantation Society (TTS); and received an American College Medical School John Warren Surgical and was the senior author on the of Surgeons (ACS) Faculty Research Society Banquet. abstract that won the People’s Choice Fellowship Award. Award at the 2020 American Transplant Ali Salim, MD, was elected to the Mass Congress (ATC). Elizabeth Mittendorf, MD, PhD, was General Brigham Board of Directors; was named co-leader of the Breast Cancer selected as a board member of Boston Ravindra Uppaluri, MD, PhD, was Program for the Dana-Farber/Harvard MedFlight; was appointed as the critical selected to serve as the American Cancer Center; and was appointed care lead for the Brigham inpatient Society of Clinical Oncology (ASCO) Head chair of the American Society of Clinical Recover & Reimagination; and presented and Neck Cancer Scientific Program track Oncology (ASCO) and the Society for grand rounds at Cedars-Sinai Medical leader. Immunotherapy of Cancer (SITC) Annual Center and Georgetown University as Meeting. part of the Functional Outcomes and Jon O. Wee, MD, was elected to the Recovery after Trauma Emergencies editorial board of Current Challenges in Matthew Mossanen, MD, MPH, was (FORTE) project. Thoracic Surgery. awarded the New Discoveries Research Young Investigator Award for Patient Marcus Semel, MD, MPH, was selected Anna Weiss, MD, served as the chair Centered Clinical Research from the to participate in the Society for Vascular of the Society of Surgical Oncology Bladder Cancer Advocacy Network Surgery (SVS) Leadership Development (SSO) Fellows and Young Attendings (BCAN). Program. Subcommittee. Melissa M. Murphy, MD, MPH, was Eric Sheu, MD, PhD, received the named chief of Surgery at Kent Hospital. 2020 Foundation Fellowship from the American Surgical Association (ASA). BWH DOS 51

Development A gift with immediate, life-saving impact This past spring, David Canepari, a patient, benefactor and volunteer leader at Brigham and Women’s Hospital, was inspired to give after hearing about the power of a specialized life support machine and what it can do for patients. A member of the Lung Center Advisory Board, Canepari learned about the hospital’s need for additional machines called ECMO (extracorporeal membrane oxygenation) from Lung Center co- directors, Raphael Bueno, MD, and Bruce Levy, MD. Eager to help the Brigham expand its impact on patients and families, Canepari and his wife, Diane, pledged $300,000.“ECMO takes over the work of a patient’s lungs and heart temporarily,” Dr. Bueno said. “This crucial technology enables patients with severe lung or heart damage to survive until they can recover. It’s a bridge therapy for people who are waiting for lung transplants, as well as for patients with pneumonia, severe respiratory infections and heart failure.” Canepari was impressed to learn the machine can sustain a patient’s life for days or weeks. “Both Dr. Bueno and Dr. Levy emphasized that the Brigham needs to expand the number of ECMO machines because they save lives,” he said. The Caneparis began giving to the Brigham in 2017 in gratitude for the care David received from Dr. Bueno. Their philanthropy has supported a comprehensive lung screening program, the thoracic surgery fellowship program and research within the Lung Center. “While research is important, it can take years to realize the benefits,” Canepari said. “With ECMO, the impact on saving lives is immediate. This means so much to me.” “We are incredibly grateful to David and Diane for their generous gift. The ultimate beneficiaries of this philanthropy are the patients who will get another chance to survive, recover and resume their lives,” Dr. Bueno said.  52 BWH DOS

Logues’ philanthropy champions thoracic surgery When Jim Logue’s mother, Sue, of their philanthropic priorities for the developed lung cancer in 1999, her past two decades. Recently, they gave local pulmonologist in Pennsylvania $150,000 to support thoracic surgery recommended she seek a second opinion fellow training under Dr. Swanson’s from a hospital with more experience direction. They also joined the hospital’s handling very complex cases. A colleague Lung Center Advisory Board. encouraged Logue to contact Scott Swanson, MD, director of Minimally “Jim and Marie generously give of Invasive Thoracic Surgery at Brigham and themselves to enhance the training Women’s Hospital. and care we provide,” Dr. Swanson said. “I’m tremendously grateful for their “Dr. Swanson told us the Brigham’s thoughtfulness and friendship.” advanced surgical techniques gave him reason to be optimistic, and he operated “We live outside Philadelphia, near a few weeks later,” Logue remembered. some of the best health care institutions “My mom lived 10 more years—the in the world—yet we will always go to best decade of her life. She traveled, the Brigham for care. Our friends and played golf and spent time with her family have approached the Brigham grandchildren. He made that possible.” for complex medical needs, and the answer has always been, ‘yes.’ How do In gratitude and with deep respect you put a price on that? The return is for Dr. Swanson’s life-changing care, immeasurable,” Marie Logue said.  the Logues have made the Brigham one Matchetts’ gift advances breast cancer therapies Boston area native Rebecca Matchett recalls loved ones regularly turning to Brigham and Women’s Hospital throughout the years— especially her mother, who received treatment for breast cancer and leukemia. “When my sister and I learned of our inherited breast cancer gene mutation, we both went to the Brigham for preventive mastectomies,” Matchett said. “I was living in New York City by then, but there’s nowhere else I would want to go.” It was Mehra Golshan, MD, MBA, the former Dr. Abdul Mohsen and Sultana Al-Tuwaijri Distinguished Chair in Surgical Oncology at the Brigham, who performed the sisters’ mastectomies—and who later oversaw Matchett’s surgical care when she developed breast cancer. In gratitude for her care, Matchett and her husband, Chris, recently committed $150,000 to the Brigham to propel breast cancer research. Their gift will advance investigations of therapeutic approaches, including elective mastectomies to reduce breast cancer risk and how these approaches affect patients’ lives in the following years. “I have many world-class hospitals a stone’s throw from home, so it’s a real testament for someone from New York City to keep going back to the Brigham,” Matchett, who also serves on the hospital’s Cancer Research and Care Advisory Board, said. “Chris and I are so happy to support the hospital’s amazing work.”  BWH DOS 53

Satters spark robotic approach Support the Work to cancer surgery of the Department of Surgery Two years ago, after doctors in Florida diagnosed Susan Satter’s Each year, thousands of people entrust father with pancreatic cancer, they the Department of Surgery at Brigham determined the best chance of Health to provide them with excellent prolonging his life was to perform a medical care. Many turn to us because complex operation called a Whipple of our long history of medical firsts procedure. During this risky surgery, and reputation for attracting the doctors remove the gall bladder finest surgical trainees and surgeons and bile duct, along with cancerous in the country. One of the reasons portions of the pancreas, small we have been able to build such a intestine and sometimes a portion of strong program—and to establish new the stomach. standards of surgical care—is because of philanthropic contributions from people Satter and her husband, Stewart, like you. patients and benefactors at Brigham and Women’s Hospital, recently Gifts from our alumni, patients and learned about the hospital’s plans to friends help us to train our staff in the develop a robotic, minimally invasive latest surgical techniques, to make Whipple procedure that could offer advances in surgery through research faster recovery with better results. and to achieve the best possible Knowing what a difference this could outcomes for patients. When you make make for patients like Satter’s father, a gift to the Department of Surgery, they contributed $1.25 million to establish the Susan and Stewart Satter you enable our medical team to provide Robotic Whipple Surgery Program. Their gift will help the Brigham develop a the most advanced care and make a minimally invasive simulation model, train surgeons and robotic assistants, difference for every patient and family and conduct a series of surgeries to assess and improve the approach. member we see. The surgery program—the first of its kind in Boston—is led by Thomas Clancy, MD, a surgical oncologist the Satters have come to know and trust. For more information if you are Ten years ago, after Satter came to the Brigham for a back X-ray, radiologists interested in making a gift to the detected a cyst in her pancreas. Dr. Clancy ordered follow-up scans every 6 to Department of Surgery at Brigham 12 months to monitor her condition, which has remained stable. and Women’s Hospital, or to a specific “The Brigham has been terrific to our entire family,” Satter said. Brigham physician or scientist within the physicians also helped her mother and sister contend with cancer. department, please contact Susan Dr. Clancy reciprocates this gratitude. “Thanks to Susan and Stewart’s Andrews, assistant vice president, generosity, we are able to develop a comprehensive program of robotic Development Office, at 617.424.4349 or pancreatic surgery. At the Brigham, we’re always looking for innovative ways to [email protected]. ª deliver the safest, most effective surgical care possible, and this gift helps us achieve that goal.” Brigham Surgery Developing this surgical approach means so much to the Satters. “It took Alumni my dad about six months to recover from Whipple surgery and rehab, a challenging experience for our whole family,” Satter said. “We want to help find The BWH Surgery Alumni Group new ways to perform this surgery for others like my dad.” consists of graduates of Brigham and “There’s no better place to be philanthropic than at the Brigham. We’re Women’s Hospital surgery residency excited to see the successes of Tom and his team. They give us all hope,” and fellowship programs and former Stewart Satter said.  Department of Surgery faculty members. If you would like to join the BWH Surgery Alumni Group and receive news and updates from the Department of Surgery, please visit: bwhsurgerynews.partners.org/alumni or email us at: [email protected]. ª 54 BWH DOS

Leadership Division Administrators Gerard M. Doherty, MD Shawn S. Bonk Moseley Professor of Surgery, Harvard Medical School Breast Surgery Surgeon-in-Chief, Brigham Health & Dana-Farber Cancer Institute Crowley Family Distinguished Chair, Department of Surgery, Keila L. Jackson, MHA Brigham and Women’s Hospital Cardiac Surgery C. Keith Ozaki, MD Jennifer Fanning Vice Chair, Department of Surgery, Brigham and Women’s Hospital General and Gastrointestinal Surgery John A. Mannick Professor of Surgery, Brigham and Women’s Hospital Professor of Surgery, Harvard Medical School Nathan J. Burke, MBA Oral Medicine Douglas S. Smink, MD, MPH Chief of Surgery, Brigham and Women’s Faulkner Hospital Glen L. Palmer, MBA, FACHE Associate Chair of Education Otolaryngology – Head and Neck Surgery Ronald Bleday, MD Shannon Weiss, RN, MBA Associate Chair of Quality and Patient Safety Plastic and Reconstructive Surgery Tari A. King, MD Courtney Andrade, MSM Associate Chair of Multidisciplinary Oncology Surgical Oncology Elizabeth Mittendorf, MD, PhD Philip Girard, MS Associate Chair of Research Thoracic Surgery Louis L. Nguyen, MD, MPH, MBA Lorraine T. Levitsky (interim) Associate Chair of Digital Health Systems Transplant Surgery Malcolm K. Robinson, MD Suzanna Clark, MHA Associate Chair of Clinical Operations Trauma, Burn and Surgical Critical Care Ali Salim, MD Sandra Doolan, MBA Associate Chair of Surgical Critical Care Urology Jennifer Shin, MD, SM Lorraine T. Levitsky Associate Chair of Faculty Development Vascular and Endovascular Surgery Philip D. Roberts, MBA CONTACT US Executive Administrator Department of Surgery Sarah Broughton Herd 75 Francis Street Director, Surgery Education Office Tower 1 – Room 110 Boston, MA 02115 Jamie Fu, MBA [email protected] Senior Administrative Director of Research 617.732.8181 Kevin T. Hart, MBA FOLLOW US Senior Director of Operations twitter.com/bwhsurgery Matthew S. Sandler, MBA Senior Director of Finance David A. Steger, MS in CREDITS Director of Communications DESIGN • one2tree PHOTOGRAPHY • Cover: Craig F. Walker/The Boston Globe Victoria (Tori) Wilmarth, MBA Pg. 4, 6, 18 & 47: James P. Rathmell, MD Pg. 21: Max Esposito Director of Network Strategy touch! stay

Brigham Surgery is committed to delivering world-class, collaborative patient care with a profoundly human touch, while advancing scientific research and training the surgical innovators of tomorrow. brighamandwomens.org/surgery

Department of Surgery 2019 ANNUAL REPORT

DEPARTMENT OF SURGERY by the numbers 37 161 5 Fellows Faculty ACGME-Accredited Surgical Fellowships 5 31,720 Operations Performed ACGME-Accredited Surgical Residency Programs 214 12 150 Active Grants Interns And Residents Clinical Divisions 40 171,027 Office Visits Active Clinical Trials $39,447,056 Research Spending

A Letter from the Chair For over a century, Brigham and Women’s Hospital and its predecessors have made incredible contributions to advance the field of surgery, in large part due to the people who have been drawn to come to our campus to work. Everyday our surgeons and teams deliver world-class collaborative patient care while advancing scientific research and training the surgical innovators of tomorrow. Over the past year, the Department of Surgery has continued to build on our proud history of clinical and academic achievement. We saw our faculty continue to grow as we welcomed the following new members to our group: Gustavo J. Bauzá, MD, Trauma, Burn, Surgical and Critical Care; Regan W. Bergmark, MD, Otolaryngology – Head and Neck Surgery; Antonio Coppolino, III, MD, MSc, Thoracic Surgery; Mark Fairweather, MD, Surgical Oncology; Matthew D. Ingham, MD, Urology; Matthew Mossanen, MD, MPH, Urology; Anju K. Patel, MD, Otolaryngology – Head and Neck Surgery; Steven Piantadosi, MD, PhD, Surgical Oncology; and Matthew M. Rochefort, MD, Thoracic Surgery. We also named new department leaders this academic year. Zara Cooper, MD, MSc, was appointed Kessler Director of the Center for Surgery and Public Health (CSPH); Elizabeth A. Mittendorf, MD, PhD, was named associate chair for Research; Louis L. Nguyen, MD, MPH, MBA, was named associate chair for Digital Health Systems; and Ali Salim, MD, was named associate chair of Surgical Critical Care. Our department continues to be on the cutting edge of surgical research with new grant funding to study combination therapy in triple-negative breast cancer (TNBC) patients; to examine non-small cell lung cancer tumors to help cancer immunotherapy efforts; and to measure Multiple Object Awareness (MOA) capacity (a form of spatial long-term memory) to track information in a dynamic world as it relates to our visual intelligence. This year we opened our new state-of-the-art Lung Center. As a Center of Excellence at the Brigham, the Lung Center provides clinical care for all lung-based diagnoses by bringing together more than 30 clinical and research programs and is an excellent model of multidisciplinary clinical care. Our annual report highlights just some of the many examples of our ongoing commitment to excellence in clinical care, research and surgical education. Thank you for taking the time to read our report, we look forward to connecting with you again soon. GERARD M. DOHERTY, MD Moseley Professor of Surgery, Harvard Medical School Surgeon-in-Chief, Brigham Health & Dana-Farber Cancer Institute Crowley Family Distinguished Chair, Department of Surgery, Brigham and Women’s Hospital BWH DOS 3

Faculty DEPARTMENT OF SURGERY Brigham and Women’s Hospital attracts internationally renowned surgeons who create pioneering breakthroughs that make a difference for patients today as well as for generations to come. We are committed to delivering world-class, collaborative patient care with a profoundly human touch, while advancing scientific research and training the surgical innovators of tomorrow. BREAST SURGERY CARDIAC SURGERY TARI A. KING, MD PREM S. SHEKAR, MD Chief • Division of Breast Surgery Chief • Division of Anne E. Dyson Associate Professor of Surgery in Cardiac Surgery the Field of Women’s Cancers Associate Professor of Surgery Thanh U. Barbie, MD Elizabeth Mittendorf, MD, PhD Instructor in Surgery Robert and Karen Hale Distinguished Chair Sary F. Aranki, MD in Surgical Oncology Associate Professor of Surgery Katherina Zabicki Calvillo, MD Associate Professor of Surgery Instructor in Surgery Tsuyoshi Kaneko, MD Faina Nakhlis, MD Assistant Professor of Surgery Laura S. Dominici, MD Assistant Professor of Surgery Assistant Professor of Surgery Dan Loberman, MD Suniti Nimbkar, MD Instructor in Surgery Margaret M. Duggan, MD Instructor in Surgery Chief Medical Officer, Paul Pirundini, MD Brigham and Women’s Faulkner Hospital Esther Rhei, MD Instructor in Surgery Assistant Professor of Surgery Assistant Professor of Surgery James D. Rawn, MD Mehra Golshan, MD, MBA Anna Weiss, MD Instructor in Surgery Dr. Abdul Mohsen and Assistant Professor of Surgery Sultana Al-Tuwaijri Distinguished Chair in Surgical Oncology Associate Professor of Surgery 4 BWH DOS

GENERAL AND GASTROINTESTINAL SURGERY ALI TAVAKKOLI, MD Interim Chief • Division of General and Gastrointestinal Surgery Associate Professor of Surgery Colon and Metabolic and Minimally Invasive Rectal Surgery Bariatric Surgery Surgery (MIS) RONALD BLEDAY, MD SCOTT A. SHIKORA, MD Stanley W. Ashley, MD Section Chief • Colon Section Chief • Metabolic Frank Sawyer Professor of Surgery and Rectal Surgery and Bariatric Surgery Associate Professor of Surgery Professor of Surgery David C. Brooks, MD Associate Professor of Surgery Christian H. Corwin, MD Neil D. Ghushe, MD Instructor in Surgery Instructor in Surgery Douglas S. Smink, MD, MPH Associate Professor of Surgery Joel E. Goldberg, MD Malcolm K. Robinson, MD Assistant Professor of Surgery Associate Professor of Surgery Edward E. Whang, MD Associate Professor of Surgery Jennifer L. Irani, MD Eric G. Sheu, MD, PhD Assistant Professor of Surgery Assistant Professor of Surgery General Surgeons Nelya Melnitchouk, MD, MSc David Spector, MD John J. Froio, MD Assistant Professor of Surgery Instructor in Surgery Instructor in Surgery Melissa M. Murphy, MD, MPH Ashley H. Vernon, MD Pardon R. Kenney, MD, MMSc Instructor in Surgery Instructor in Surgery Senior Lecturer on Surgery Paul B. Davidson, PhD Erika L. Rangel, MD, MS Instructor in Psychiatry Assistant Professor of Surgery Mark Gorman, PhD Brent T. Shoji, MD Instructor in Psychiatry Assistant Professor of Surgery BWH DOS 5

ORAL MEDICINE OTOLARYNGOLOGY– PLASTIC AND HEAD AND NECK SURGERY RECONSTRUCTIVE SURGERY NATHANIEL S. TREISTER, DMD, DMSc RAVINDRA UPPALURI, MD, PhD ANDREA L. PUSIC, MD, MHS Chief • Division of Oral Medicine Chief • Division of Chief • Division of Plastic Associate Professor of Oral Otolaryngology–Head and Neck and Reconstructive Surgery Medicine, Infection, and Immunity Surgery Joseph E. Murray Professor BWH Distinguished Chair in of Surgery Vidya Sankar, DMD, MHS Otolaryngology Assistant Professor of Oral Associate Professor of Otolaryngology Matthew J. Carty, MD Medicine, Infection, and Immunity Associate Professor of Surgery Donald J. Annino, DMD, MD Stephen T. Sonis, DMD, DMSc Assistant Professor of Otolaryngology Benjamin P. Christian, MD Professor of Oral Medicine, Instructor in Surgery Infection, and Immunity Regan Bergmark, MD Instructor in Otolaryngology Yoon S. Chun, MD Herve Y. Sroussi, DMD, PhD Associate Professor of Surgery Associate Professor of Oral Thomas L. Carroll, MD Medicine, Infection, and Immunity Assistant Professor of Otolaryngology Jessica Erdmann-Sager, MD Instructor in Surgery Alessandro Villa, DMD, MPH, PhD Carleton Eduardo Corrales, MD Assistant Professor of Oral Instructor in Otolaryngology Lydia A. Helliwell, MD Medicine, Infection, and Immunity Instructor in Surgery Laura A. Goguen, MD Sook-Bin Woo, DMD, MMSc Associate Professor of Otolaryngology Charles A. Hergrueter, MD Associate Professor of Oral Medicine, Assistant Professor of Surgery Infection, and Immunity Alice Z. Maxfield, MD Instructor in Otolaryngology Dennis P. Orgill, MD, PhD Professor of Surgery Anju K. Patel, MD Instructor in Otolaryngology Bohdan Pomahac, MD Roberta and Stephen R. Weiner Anthony A. Prince, MD Distinguished Chair in Surgery Instructor in Otolaryngology Professor of Surgery Rachel E. Roditi, MD Christian E. Sampson, MD Instructor in Otolaryngology Assistant Professor of Surgery Jennifer J. Shin, MD Indranil Sinha, MD Associate Professor of Otolaryngology Assistant Professor of Surgery Simon G. Talbot, MD Associate Professor of Surgery

SURGICAL ONCOLOGY THORACIC SURGERY CHANDRAJIT P. RAUT, MD, MSc RAPHAEL BUENO, MD Interim Chief • Division of Chief • Division of Thoracic Surgical Oncology Surgery Professor of Surgery Fredric G. Levin Distinguished Chair in Thoracic Surgery and Lung Cancer Monica M. Bertagnolli, MD Research Richard E. Wilson Professor of Surgery Professor of Surgery in the Field of Surgical Oncology Antonio Coppolino, III, MD, MSc Thomas E. Clancy, MD Instructor in Surgery Assistant Professor of Surgery Christopher T. Ducko, MD Mark Fairweather, MD Assistant Professor of Surgery Assistant Professor of Surgery Michael T. Jaklitsch, MD Jiping Wang, MD, PhD Professor of Surgery Associate Professor of Surgery Abraham Lebenthal, MD, MHA Charles H. Yoon, MD, PhD Instructor in Surgery Assistant Professor of Surgery Hari R. Mallidi, MD Endocrine Surgery Associate Professor of Surgery FRANCIS D. MOORE, JR., MD Ciaran McNamee, MD, MSc Section Chief • Endocrine Assistant Professor of Surgery Surgery Francis D. Moore Professor of Steven J. Mentzer, MD Surgery Professor of Surgery Nancy L. Cho, MD Namrata Patil, MD, MPH Assistant Professor of Surgery Instructor in Surgery Gerard M. Doherty, MD Matthew M. Rochefort, MD Moseley Professor of Surgery Instructor in Surgery Atul A. Gawande, MD, MPH Scott J. Swanson, MD Cynthia and John F. Fish Professor of Surgery Distinguished Chair in Surgery Samuel O. Thier Professor of Hisashi Tsukada, MD, PhD Surgery Instructor in Surgery Matthew A. Nehs, MD Jon O. Wee, MD Assistant Professor of Surgery Assistant Professor of Surgery Brian Whang, MD Instructor in Surgery Abby A. White, DO Assistant Professor of Surgery Daniel C. Wiener, MD Instructor in Surgery BWH DOS 7

TRANSPLANT SURGERY TRAUMA, BURN, SURGICAL UROLOGY AND CRITICAL CARE STEFAN G. TULLIUS, MD, PhD ALI SALIM, MD ADAM S. KIBEL, MD Chief • Division of Transplant Chief • Division of Trauma, Burn, Chief • Division of Urology Surgery Surgical and Critical Care Elliott Carr Cutler Professor Professor of Surgery Professor of Surgery of Surgery Sanjay Kumar, MD Reza Askari, MD Steven L. Chang, MD, MS Associate Professor of Surgery Assistant Professor of Surgery Assistant Professor of Surgery Sayeed K. Malek, MD Gustavo J. Bauzá, MD Elodi J. Dielubanza, MD Assistant Professor of Surgery Instructor in Surgery Christopher J. Burns, MD Instructor in Surgery George Haleblian, MD Assistant Professor of Surgery Cristina Carpio, MD Instructor in Surgery Matthew D. Ingham, MD Member of the Faculty of Surgery Zara R. Cooper, MD, MSc Associate Professor of Surgery Martin Kathrins, MD Instructor in Surgery David W. Fink, MD Instructor in Surgery Michael J. Malone, MD Instructor in Surgery Joaquim M. Havens, MD Assistant Professor of Surgery Michael W. McDonald, MD Assistant Professor of Surgery Stephanie L. Nitzschke, MD, MS Instructor in Surgery Matthew Mossanen, MD, MPH Assistant Professor of Surgery Robert Riviello, MD, MPH Assistant Professor of Surgery Michael P. O’Leary, MD, MPH Professor of Surgery Naomi Shimizu, MD Instructor in Surgery Mark A. Preston, MD, MPH Assistant Professor of Surgery Graeme S. Steele, MD Assistant Professor of Surgery Quoc-Dien Trinh, MD Associate Professor of Surgery

VASCULAR AND Research Steven Piantadosi, MD, PhD ENDOVASCULAR SURGERY Senior Investigator Assunta De Rienzo, PhD Member of the Faculty of Surgery MICHAEL BELKIN, MD Lead Investigator Chief • Division of Vascular and Assistant Professor of Surgery William G. Richards, PhD Endovascular Surgery Lead Investigator Professor of Surgery Ann Marie Egloff, PhD, MPH Assistant Professor of Surgery Lead Investigator Garima Dosi, MD Member of the Faculty of Surgery Joel S. Weissman, PhD Edwin C. Gravereaux, MD Senior Investigator Instructor in Surgery Li Jia, PhD Professor of Surgery Lead Investigator Lindsey Korepta, MD Assistant Professor of Surgery Jeremy M. Wolfe, PhD Edward M. Kwasnik, MD Senior Investigator Assistant Professor of Surgery Raouf A. Khalil, MD, PhD Professor of Ophthalmology Lead Investigator Edward J. Marcaccio, Jr., MD Associate Professor of Surgery Feng Yao, PhD Assistant Professor of Surgery Lead Investigator James A. Lederer, PhD Associate Professor of Surgery Matthew T. Menard, MD Lead Investigator Associate Professor of Surgery Associate Professor of Surgery Louis L. Nguyen, MD, MPH, MBA EMERITUS Cardiac Surgery Associate Professor of Surgery Anthony D. Whittemore, MD Miguel Haime, MD C. Keith Ozaki, MD Professor of Surgery, Emeritus Jacquelyn A. Quin, MD Professor of Surgery Marco Zenati, MD Michael J. Zinner, MD Marcus E. Semel, MD, MPH Moseley Professor of Surgery, Emeritus Plastic Surgery Instructor in Surgery AFFILIATED FACULTY Shahe Fereshetian, MD South Shore Hospital Urology Frederick Millham, MD B. Price Kerfoot, MD Chair of Surgery, South Shore Hospital Vascular Surgery Veteran’s Affairs (VA) Boston Healthcare System Michelle C. Martin, MD Joseph Raffetto, MD General Surgery Research Kamal Itani, MD Chief of Surgery, VA Boston Health Vivian Cristofaro, PhD Care System Aldebaran Hofer, MD, PhD Jason S. Gold, MD Maryrose P. Sullivan, PhD Gentian Kristo, MD Ann Smith MD, MPH BWH DOS 9

NEW DIVISION CHIEF Dr. King currently serves on the LOUIS L. NGUYEN, MD, MPH, MBA Steering Committee for the Translational Associate Chair for Digital Health TARI A. KING, MD Breast Cancer Research Consortium Systems Chief • Division of Breast Surgery (TBCRC), the National Institute of Cancer Anne E. Dyson Associate Professor of (NCI) Breast Oncology Local Disease Dr. Nguyen has been Surgery in the Field of Women’s Cancers (BOLD) Task Force and the 2019 American appointed associate chair Association for Cancer Research (AACR) for Digital Health Systems Dr. King has been Cancer Progress Report. She is also a in the Department of named the inaugural member of the Executive Council and the Surgery (DoS). In this chief of the newly chair of the Quality Committee for the newly created role, Dr. formed Division of Society of Surgical Oncology (SSO). ª Nguyen will be accountable for the design Breast Surgery at and implementation of the electronic Brigham and Women’s NEW ASSOCIATE CHAIRS health record and other information Hospital. Dr. King is the Anne E. Dyson systems across the DoS. Associate Professor of Surgery in the Field ELIZABETH A. MITTENDORF, MD, PhD Dr. Nguyen will both lead and enable of Women’s Cancers at Harvard Medical Associate Chair for Research digital practice innovation with the goals School. She serves as the associate of increasing practice efficiency and chair of Multidisciplinary Oncology Dr. Mittendorf has been safety, enabling practice growth through in the Department of Surgery as well appointed associate novel patient management interactions as the director of the Breast Cancer chair for Research in the and optimizing the DoS provider-facing Personalized Risk Assessment, Education Department of Surgery presence in eCare. In addition, he will and Prevention (B-PREP) Program at the (DoS). In this role, Dr. advise the various Brigham Health (BH) Brigham. Mittendorf will chair the IT committees and work with DoS faculty Dr. King received her medical degree DoS Research Committee. members and leadership to continually from University of Colorado Health The Research Committee has oversight evolve our information systems in a Sciences Center and completed a general and advisory responsibility for the Surgical progressive manner. ª surgery residency at Ochsner Clinic Research Office and research activities Foundation Hospital (now Ochsner of the DoS, including the review and ALI SALIM, MD Medical Center). Dr. King completed both recommendation of funding support Associate Chair of Surgical a surgical research fellowship and a breast for DoS research activities, specifically Critical Care surgery clinical fellowship at Memorial including bridge funding and utilization of Sloan Kettering Cancer Center. Her clinical start-up funding. The Research Committee Dr. Salim has been and research efforts focus on improving also oversees the general surgery resident appointed associate clinical management strategies for research placement and funding process. chair of Surgical Critical women at high risk of developing breast Dr. Mittendorf is an established Care in the Department cancer with a special emphasis on lobular researcher and well-positioned to mentor of Surgery at Brigham carcinoma in situ and atypical hyperplasia. DoS researchers, particularly regarding and Women’s Hospital. She also has an interest in the role of research funding strategies, as well as In this new role, Dr. Salim is accountable surgery in stage IV breast cancer and guiding enterprise-wide innovations in for the 24-hour operational management, through the Translational Breast Cancer surgery research. ª implementation and evaluation of staff Research Consortium (TBCRC) she and patients on the Surgical Intensive Care successfully initiated and completed Units (SICU), including general surgery, accrual to a multi-center trial addressing trauma/burn, thoracic and cardiac surgery. this issue. Additionally, he will collaborate with She has received several awards to the medical directors and chiefs of the support her work on high-risk breast Divisions of Trauma, Burn, Surgical and lesions, including the Society of Surgical Critical Care, General and Gastrointestinal Oncology (SSO) Clinical Investigator Surgery, Thoracic Surgery, Cardiac Award in Breast Cancer Research (2008), Surgery and the chair for the Department a Career Catalyst Research Award (2009), of Surgery in the development of SICU an Investigator-Initiated Research Award service programs and processes to serve (2012) and a leadership grant from the the inpatient, outpatient and community Susan G. Komen for the Cure Foundation needs, with implementation of effective (2016). Most recently, she was awarded cost containment measures. ª a development grant from the Brigham Precision Medicine Program (2018-19). 10 BWH DOS

NEW FACULTY and skull base, chronic rhinosinusitis, MARK FAIRWEATHER, MD tumors of the sinuses, aspirin exacerbated Surgical Oncology GUSTAVO J. BAUZÁ, MD respiratory disease, as well as general Trauma, Burn, Surgical and otolaryngology. In addition to research Dr. Fairweather is a Critical Care on chronic sinusitis and other sinonasal graduate of Hanover disorders, she studies disparities in health College and received his Dr. Bauzá is a graduate care outcomes and utilization of patient- medical degree from the of Villanova University reported outcomes measures across University of Louisville and received his diverse patient populations. ª School of Medicine. He medical degree from completed a residency in general surgery the Universidad Central ANTONIO COPPOLINO, III, MD, MSc at Brigham and Women’s Hospital followed del Caribe School of Thoracic Surgery by a fellowship in complex general surgical Medicine in Bayamón, Puerto Rico. He oncology at Massachusetts General completed a residency in general surgery Dr. Coppolino Hospital and Brigham and Women’s at Boston University School of Medicine is a graduate of Hospital. followed by a fellowship in surgical critical the University of He is board certified by the American care at Rutgers Robert Wood Johnson Pennsylvania and Board of Surgery (ABS) in general surgery. Medical School. received his medical Dr. Fairweather’s clinical interests He is board certified by the American degree from George include: Cancers of the gastrointestinal Board of Surgery (ABS) in general surgery Washington University School of Medicine tract and soft-tissue sarcomas. In addition and surgical critical care. His research and and Health Sciences. He also holds an MSc to research on treatment outcomes clinical interests include: Management and in clinical and translational science from for sarcoma, including retroperitoneal outcomes in both trauma and sepsis. ª Weill Cornell Graduate School of Medical sarcomas and gastrointestinal stromal Sciences. tumors, he also serves as an executive REGAN W. BERGMARK, MD He completed a residency in general officer for the Alliance Foundation Trials, Otolaryngology – Head and surgery at New York-Presbyterian Hospital/ LLC (AFT), where his work focuses on Neck Surgery Weill Cornell Medical Center followed by a developing and validating methods of residency in thoracic surgery at Brigham capturing high-quality real-world data Dr. Bergmark is a and Women’s Hospital. Most recently, alongside ongoing clinical trials. ª graduate of Stanford Dr. Coppolino completed his fellowship University and was a in heart and lung transplantation and MATTHEW D. INGHAM, MD John Gardner Public mechanical circulatory support at the Urology Service fellow prior to Brigham. receiving her medical He is board certified by the American Dr. Ingham is a graduate degree from Harvard Medical School. Board of Surgery (ABS) and the American of the University of She completed her residency training in Board of Thoracic Surgery (ABTS). Toronto and received the Harvard Otolaryngology Residency His research and clinical interests his medical degree from Program followed by a fellowship in include: Thoracic surgical oncology, end- Eastern Virginia Medical rhinology and anterior skull base surgery stage heart and lung disease, mechanical School, where he also at Massachusetts Eye and Ear/Harvard circulatory support, lung and heart trans- completed his residency in reconstructive Medical School. At Massachusetts Eye and plantation and ex vivo lung perfusion surgery and pelvic health. He completed Ear, Dr. Bergmark was then the Gliklich (EVLP). ª the combined Harvard urologic oncology Healthcare Innovation Scholar where she fellowship at Massachusetts General collaborated with Massachusetts Eye and Hospital and Brigham and Women’s Ear, Harvard Medical School, Harvard Hospital. Business School and the International His research and clinical interests Consortium for Health Outcomes include: Benign prostatic hyperplasia, Measurement (ICHOM) on standardized bladder cancer, hydronephrosis, kidney health outcomes measures. cancer, kidney masses/cysts, laparoscopic Dr. Bergmark is board certified by the surgery, penile cancer, prostate cancer, American Board of Otolaryngology – Head robotic surgery and testicular cancer. ª and Neck Surgery (ABOHNS). Her clinical interests include: Diseases of the sinuses BWH DOS 11

IN MEMORIAM MATTHEW MOSSANEN, MD, MPH STEVEN PIANTADOSI, MD, PhD Urology Surgical Oncology John A. Mannick, MD 1928 - 2019 Dr. Mossanen is Dr. Piantadosi joined a graduate of the Brigham and Women’s Dr. Mannick served as Moseley University of California, Hospital as the new Professor of Surgery at Harvard Los Angeles, where he associate senior Medical School between 1976 received his medical biostatistician, Division and 1994. He was a national and degree from the David of Surgical Oncology. international leader in vascular Geffen School of Medicine. He also holds a He received his medical degree from the surgery and surgical research Master of Public Health from the Harvard University of North Carolina at Chapel and a dedicated educator who T.H. Chan School of Public Health. Dr. Hill School of Medicine followed by a PhD provided seminal contributions in Mossanen completed a residency in in biomathematics at the University of transplantation immunology and urology from the University of Washington Alabama at Birmingham. After six years in understanding the role of the School of Medicine followed by the as staff fellow at the National Cancer intrinsic immune system in burns combined Harvard urologic oncology Institute (NCI), he joined the Department and other forms of acute injury. fellowship at Massachusetts General of Oncology at the Johns Hopkins Medical Hospital and Brigham and Women’s Institutions as director of Biostatistics. Dr. Mannick contributed many Hospital. He rose through the ranks as professor successful techniques to the His research and clinical interests of oncology for the Departments of practice of vascular surgery, include: Benign prostatic hyperplasia, Biostatistics and Epidemiology at Johns including the use of vein grafts to bladder cancer, kidney cancer, kidney Hopkins Bloomberg School of Public reconstruct the tibial and peroneal masses/cysts, laparoscopic surgery, penile Health. In 2007, he moved to Cedars- arteries and the reduction of cancer, prostate cancer, robotic surgery Sinai Medical Center, where he served as mortality from abdominal aortic and testicular cancer. ª the first director of the Samuel Oschin aneurysm repair from more than Comprehensive Cancer Institute for 10 five percent to less than two percent years. ª through the use of volume loading and minimal dissection of the ANJU K. PATEL, MD MATTHEW M. ROCHEFORT, MD aorta and iliac arteries. In addition, Otolaryngology – Head and Thoracic Surgery he also contributed to the use of Neck Surgery axillo-femoral and femoro-femoral Dr. Rochefort is grafts to correct aortoiliac occlusive Dr. Patel is a graduate a graduate of the disease in certain high-risk patients, of George Washington University of Miami, as well as the demonstration that University School of where he also received autogenous tissue reconstruction Medicine and Health his medical degree techniques can be applied with very Sciences. She completed from the Leonard M. high rates of long-term success in residency training in Miller School of Medicine. He completed over 90% of patients with limb- otolaryngology – head and neck surgery a residency in general surgery at the threatening femoropopliteal and at Tufts Medical Center followed by a University of California, Los Angeles infrapopliteal occlusive disease. fellowship in laryngology and care of the followed by a residency in thoracic surgery professional voice at Emory University. at Brigham and Women’s Hospital. Also a skilled administrator, Dr. Most recently, Dr. Patel was in private Dr. Rochefort is board certified in Mannick made a major contribution practice at ENT and Allergy Associates. general surgery by the American Board of to the growth of the Department Dr. Patel is board certified by the Surgery (ABS). of Surgery at the Brigham and the American Board of Otolaryngology – Head His research and clinical interests services it could offer during the and Neck Surgery (ABOHNS). Her clinical include: Benign esophageal pathology, planning and formation of the new interests include: Management of voice and including gastroesophageal reflux Brigham and Women’s Hospital, swallowing disorders, minimally invasive disease (GERD) and achalasia, esophageal which opened in 1980. ª surgical techniques and in-office laryngeal cancer, lung cancer, minimally invasive procedures. Additionally, her research surgery, thymoma and thymic carcinoma, interests include vocal fold paralysis, the robotic surgery, and medical and surgical aging larynx and chronic dysphagia. ª education. ª

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The Brigham lung center opens its doors As a Center of Excellence at Brigham multidisciplinary care for our and Women’s Hospital, the Lung patients.” Center provides clinical care for all lung-based diagnoses—from asthma, The Making of the to cystic fibrosis, to rare lung cancers Lung Center like mesothelioma—all in one place. “Initially, it was virtual to a “We are trying to break down silos great extent,” Dr. Bueno says. “The in the care of lung diseases with an pulmonary medicine and thoracic innovative approach to creating a surgery clinics were across the hall diagnosis-based outpatient clinic as from one another, and we did have opposed to a specialty-based clinic,” some joint programs, such as the lung Raphael Bueno, MD, chief of the transplant program.” Division of Thoracic Surgery and co- director of the Brigham Lung Center, The transformation process began says. “Just as a cancer center deals with a retreat and the creation of a with anything to do with cancer, the steering committee that met every Lung Center deals with anything to week for five and a half years to make do with lung diseases.” the Lung Center a reality. When space became available nearby the “This type of effort is trans- pulmonary and thoracic surgery formative,” Bruce Levy, MD, chief clinics, Drs. Bueno and Levy lobbied of the Division of Pulmonary and for that space to build the center. The Critical Care Medicine and co- Brigham facilities team renovated the director of the Brigham Lung Center, space into a beautiful, comforting and says. “By bringing together our efficient ambulatory clinical space lung providers here at the Brigham, we can provide individualized, 14 BWH DOS

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Thoracic surgeon Matthew Rochefort and thoracic surgery fellow Hassan Khalil collaborate in the Lung Center. for patients. When the Lung Center A Clinical Center lung condition, from common to opened its doors, it became fully complex to critical. Reaching across integrated with the main ambulatory of Excellence a dozen disciplines—including clinics for Pulmonary Critical Care pathology, radiology, anesthesiology, Medicine and Thoracic Surgery Individually, the Division of radiation and medical oncology, (now Lung Centers A and B), chest Thoracic Surgery and the Division otolaryngology, precision medicine imaging and thoracic radiology, and of Pulmonary and Critical Care and nursing—the center provides soon, pulmonary function testing. Medicine are ranked among the top an integrated, seamless experience such programs in the nation. The new for patients with lung conditions. It is difficult to imagine a more Lung Center provides comprehensive, For example, the Airway and fitting place for this first-of-its- customized care for all lung Breathing Disorders Programs kind center in the nation. The patients by bringing together a unites the clinical and research Brigham, along with its predecessor multidisciplinary team of medical and expertise of pulmonologists, thoracic institutions, has a long tradition of surgical experts from the pulmonary surgeons, allergists/immunologists, important medical milestones in and thoracic divisions and the Lowe otolaryngologists, oncologists and lung care—the introduction of the Center for Thoracic Oncology within occupational medicine specialists. Drinker respirator (or iron lung) that Dana-Farber/Brigham and Women’s saved a young polio patient’s life Cancer Center. Similarly, the Infectious Lung at the Peter Bent Brigham Hospital Conditions and Immunologic in 1929; and the participation of The Lung Center is an international Disorders Programs integrate Brigham surgeons in the first wave referral center, caring for the most the skills and experience of of successful lung transplants in complex patients from the United a multidisciplinary team of 1990. States and abroad. It houses 36 infectious disease physicians, specialized programs for every 16 BWH DOS

pulmonologists (with particular diagnosis, not based on specialty,” Dr. lung care, we hope that the new interest in challenging infections), Bueno explains. “If you have a cough, rheumatologists, radiologists, there are many potential causes. The Lung Center space will be a beacon pathologists, thoracic surgeons and Lung Center helps patients get to the the diagnostic microbiology and right doctors based on their issues, not of innovation in translational lung rheumatology laboratories. With based on searching for the right type integration of care from renowned of doctor.” research and education,” Dr. Levy physicians, surgeons, scientists, nurses and support staff, the Lung Empowering says. Center is poised to make great advances in the care of patients with Collaborative Care “Our goal is to provide lung diseases. Patients are not the only ones extraordinary care for any lung The Patient Experience who benefit from all their doctors being in one place. Bringing together condition by bringing together Patients who come to the Lung specialists in a collaborative clinical Center will find all their providers space improves cross-departmental more than 30 clinical and research and services located in one place— communication, teamwork, Lung Center A (Pulmonary Medicine) innovation, training, knowledge programs,” Dr. Bueno says. and Lung Center B (Thoracic Surgery), sharing and research collaboration. co-located down the hall; and Lung In partnership with the Channing “Combined with our academic Center C (International Mesothelioma Division of Network Medicine, the Program), the brand-new clinic Divisions of Pulmonary and Critical setting, it iistsoknienodf.”thªe most ambitious facility dedicated to multidisciplinary Care Medicine and Thoracic Surgery centers of lung care. Next door and across the have joined forces to create a Lung hall are the Division of Thoracic Research Center at the Brigham 36 Imaging, ambulatory radiology, Research Institute. the X-ray and CT Scan clinic, and specialized programs pulmonary function testing. Solving the mysteries of complex for every lung condition, and rare lung disorders requires from common to complex “The center is all about patient the expertise of dozens of niche to critical experience and patient care,” Dr. specialists, a full array of diagnostic Bueno says. “We believe our patients tools and a well-refined system for 30 ought to have same-day care. They sharing information. In the Lung should not have to wait another Center, the sharing of a single clinical and research month between visits.” Eliminating patient intake form across clinical, programs multiple visits and appointments is surgical and research structures is not only more convenient for patients, revolutionizing how patients with Gerard Doherty, surgeon-in-chief and Crowley but it also helps speed their recovery. lung conditions receive care. With the Family Distinguished Chair, speaks at the Lung common patient intake form, Lung Center opening. “We make every effort to help Center physicians and surgeons can patients see multiple specialists on review and share information about the same day,” Dr. Bueno says. That risk factors, heredity and clinical includes employing patient navigators impact with a precision that would to help patients take advantage of be very challenging without a unified every support service and help orient medical record. This collaborative them and their families through the workflow also sets the stage for hospital by accompanying them to physician-scientists to make life- appointments and testing. altering discoveries in lung medicine. “In the Lung Center, we’re blessed “The common patient intake form to practice with professional, simplifies information gathering from dedicated and compassionate our patients and communication flow staff who treat each patient with between our clinical lung practices,” the kindness and detailed care Dr. Levy says. “And it also helps to coordination that you would want for enable annotation for our translational your friends and family members,” biomedical research.” Dr. Levy says. “In addition to transformative “We are a one-stop shop based on BWH DOS 17

Education CURRENT RESIDENTS PGY 2 The Department of Surgery General Surgery James Etheridge, MD combines top-notch clinical Eastern Virginia Medical School care with world-class research Program Director: and cutting-edge education Douglas S. Smink, MD, MPH Jessica Feliz, MD to provide comprehensive University of Virginia School of Medicine surgical training programs. Associate Program Directors: Teaching tomorrow’s leaders Jennifer Irani, MD; Matthew Nehs, Katherine He, MD today… MD; Stephanie Nitzschke, MD, MS; University of Michigan Medical School Naomi Shimizu, MD 150 Patrick Heindel, MD Interns and Residents PGY 1 Keck School of Medicine of USC 37 CATEGORICAL Paige Newell, MD Fellows Lewis Katz School of Medicine at Temple Alexis Antunez, MD University 5 University of Michigan Medical School Mehida Rojas-Alexandre, MD ACGME-Accredited James Fitzgibbon, MD Yale School of Medicine Surgical Residency Programs Lewis Katz School of Medicine at Temple University Eva Rouanet Hendrix, MD 5 University of Massachusetts Medical School Kerri McKie, MD ACGME-Accredited University of Massachusetts Medical School Matthew Vivero, MD Surgical Fellowships Columbia University Vagelos College of Brittany Powell, MD Physicians and Surgeons 12 Stanford University School of Medicine Vanessa Welten, MD Non-ACGME-Accredited Cullen Roberts, MD Northwestern University Feinberg School of Surgical Fellowships Warren Alpert Medical School of Brown Medicine University 18 BWH DOS Christine Wu, MD Matthew Schoen, MD University of Michigan Medical School Stanford University School of Medicine PGY 3 Sarabeth Spitzer, MD Stanford University School of Medicine Sophie Hofferberth, MD University of Melbourne Medical School, Megan Sulciner, MD Australia University of Minnesota Medical School Frances Hu, MD Biqi Zhang, MD Emory University School of Medicine Harvard Medical School Lenka Ilcisin, MD PRELIMINARY Harvard Medical School Leah Ahn, MD David Mahvi, MD Tufts University School of Medicine University of Wisconsin School of Medicine and Public Health Sophie Chung, MD Yale School of Medicine Pooja Neiman, MD David Geffen School of Medicine at UCLA Ronak Jani, MD University of Pittsburgh School of Medicine Rowza Rumma, MD Stanford University School of Medicine Jared Nowell, MD Columbia University Vagelos College of Paul Salem, MD Physicians and Surgeons Mayo Clinic Alix School of Medicine Olumide Olulade, MD Elizabeth Yates, MD Howard University College of Medicine University of Michigan Medical School Sara Park, MD PGY 4 Warren Alpert Medical School of Brown University Bryan Dieffenbach, MD UC San Diego School of Medicine Ke Zhang, MD Yale School of Medicine Anthony Haddad, MD American University of Beirut Medical Center, Lebanon

Jonathan Hills-Dunlap, MD From L-R, Marko Boskovski, Peter Najjar, Melissa Mallory, Lindsey Wolf, Gerard Doherty, Stanford University School of Medicine Anupamaa Seshadri, Bethany Strong, Joseph Mets and Julius Ejiofor. George Li, MD Jamie Knell, MD Anupamaa Seshadri, MD Duke University School of Medicine UC San Diego School of Medicine Surgical Critical Care Fellowship, University of Pittsburgh School of Medicine Heather Lyu, MD Abby Larson, MD Johns Hopkins University School of Medicine Johns Hopkins University School of Medicine Bethany Strong, MD Acute Care Surgery Fellowship, University of Alessandra Moore, MD Pamela Lu, MD Maryland/R Adams Cowley Shock Trauma University of Massachusetts Medical School University of Massachusetts Medical School Center Linda Pak, MD James Luo, MD Lindsey Wolf, MD, MPH University of Michigan Medical School University of Chicago Pritzker School of Pediatric General Surgery Fellowship, Medicine Children’s Hospital of Philadelphia Nidhi Udyavar, MD George Washington University School of Arin Madenci, MD Cardiothoracic Surgery Medicine University of Michigan Medical School Integrated (I-6) Program PGY 5 Danny Mou, MD Program Director: Emory University School of Medicine Michael T. Jaklitsch, MD Alexandra Columbus, MD Sidney Kimmel Medical College at Thomas Laura Piechura, MD INTEGRATED (I-6) PROGRAM Jefferson University Stanford University School of Medicine Patrick Gedeon, MD, PGY 1 Gillian Fell, MD, PhD Jason Pradarelli, MD Duke University School of Medicine Harvard Medical School University of Michigan Medical School Rohan Shah, MD, PGY 1 David Harris, MD Lily Saadat, MD Baylor College of Medicine University of Virginia School of Medicine Northwestern University Feinberg School of Medicine Sue Wang, MD, PGY 2 Elizabeth Lilley, MD UCSF School of Medicine Rutgers Robert Wood Johnson Medical Bixiao Zhao, MD School Yale School of Medicine Hoda Javadikasgari, MD, PGY 2 Tehran University of Medical Sciences, Iran Rebecca Scully, MD 2019 GRADUATES Geisel School of Medicine at Dartmouth Kathleen Weiss, MD, PGY 3 Marko Boskovski, MD, MPH University of Miami Miller School of Medicine James Senturk, MD, PhD Cardiothoracic Surgery Fellowship, Brigham Icahn School of Medicine at Mount Sinai and Women’s Hospital RESEARCH Kristin Sonderman, MD, MPH Julius Ejiofor, MD Ariana Jones, MD University of Wisconsin School of Medicine Cardiothoracic Surgery Fellowship, Brigham UCSF School of Medicine and Public Health and Women’s Hospital Morgan Harloff, MD Russell Witt, MD Melissa Mallory, MD Kaohsiung Medical University, Taiwan UC Davis School of Medicine Breast Surgery Fellowship, Memorial Sloan Kettering Cancer Center, NY Farhang Yazdchi, MD RESEARCH Shahid Beheshti University of Medical Joseph Mets, MD Sciences, Iran Rachel Atkinson, MD Private Practice, Intercoastal Medical Group, Geisel School of Medicine at Dartmouth Sarasota, FL Yifan Zheng, MD Boston University School of Medicine Sourav Bose, MD Peter Najjar, MD, MBA Perelman School of Medicine at the Colorectal Surgery Fellowship, Brigham University of Pennsylvania and Women’s Hospital Karan Chhabra, MD University of Michigan Medical School Samuel Enumah, MD Johns Hopkins University School of Medicine Adam Fields, MD Icahn School of Medicine at Mount Sinai Sameer Hirji, MD Johns Hopkins University School of Medicine Joshua Jolissaint, MD University of Virginia School of Medicine BWH DOS 19

Otolaryngology PGY 4 Oral Medicine Program Director, Harvard Nicholas Abt, MD Program Director: Otolaryngology Residency Program: Johns Hopkins University School of Medicine Alessandro Villa, DDS, PhD, MPH Stacey T. Gray, MD Jenny Chen, MD PGY 1 Assistant Program Director: Harvard Medical School Kevin S. Emerick, MD Prazwala Chirravur, BDS Shekhar Gadkaree, MD India (certificate program) BWH Site Director: Johns Hopkins University School of Medicine Malak Al-Hadlaq, BDS Alice Z. Maxfield, MD Saudi Arabia (certificate and DMSc program) Vivek Kanumuri, MD PGY 1 Rutgers Robert Wood Johnson Medical PGY 2 School Ryan Bartholomew, MD Amal Bajonaid, BDS Harvard Medical School Ashley Miller, MD Saudi Arabia (certificate and MMSc University of Michigan Medical School program) Elliana DeVore (Kirsh), MD Yuanming Xu, DDS Harvard Medical School CHIEF RESIDENTS China (certificate and MMSc program) Rossella Intini, DDS Krish Suresh, MD Alessandra Colaianni, MD Italy (certificate program) Northwestern University Feinberg School of Johns Hopkins University School of Medicine Shaiba Sandhu, DDS Medicine UCSF School of Dentistry (certificate program) Allen Feng, MD Michael Wu, MD Johns Hopkins University School of Medicine PGY 3 Harvard Medical School Natalie Justicz, MD Nancy Wilson, DMD Roy Xiao, MD Emory University School of Medicine Augusta University School of Dentistry Case Western Reserve University School of (certificate program) Medicine Anuraag Parikh, MD Columbia University Vagelos College of 2019 GRADUATES PGY 2 Physicians and Surgeons Roxanne Bavarian, DMD Ciersten Burks, MD Alisa Yamasaki, MD University of Illinois at Chicago College of Indiana University School of Medicine Harvard Medical School Dentistry (certificate and DMSc program) Lauren Miller, MD RESEARCH Muhammad Ali Shazib, DMD Perelman School of Medicine at the Boston University Henry M. Goldman School University of Pennsylvania Phoebe Kuo Yu, MD of Dental Medicine (certificate program) Yale School of Medicine Christopher McHugh, MD, PhD Plastic Surgery Wayne State University School of Medicine Vinay Rathi, MD Yale School of Medicine Program Director, Harvard Plastic Tara Mokhtari, MD Surgery Residency Program: Stanford University School of Medicine 2019 GRADUATES Michael Yaremchuk, MD Associate Program Director: Alan Workman, MD Ashton Lehmann, MD Kyle Eberlin, MD Perelman School of Medicine at the Rhinology Fellowship, Massachusetts Eye University of Pennsylvania and Ear Infirmary INTEGRATED PROGRAM PGY 1 PGY 3 Brian Lin, MD Neurotology Fellowship, Johns Hopkins Brittany Caruso, MD Eric Barbarite, MD University School of Medicine Lewis Katz School of Medicine at Temple University of Miami Miller School of Medicine University Katie Phillips, MD Seth Fruge, MD Adeeb Derakhshan, MD Rhinology/Neurotology and Skull Base Louisiana State University School of Medicine Cleveland Clinic Lerner College of Medicine of Fellowship, Stanford University School of Case Western Reserve University Medicine Suresh Mohan, MD Yin Ren MD, PhD Warren Alpert Medical School of Brown Neurotology and Skull Base Surgery University Fellowship, UC San Diego School of Medicine Krupa Patel, MD Rosh Sethi, MD, MPH Weill Cornell Graduate School of Medical Head and Neck Oncologic Surgery Sciences Fellowship, University of Michigan Medical School Tiffany Wang, MD Keck School of Medicine of USC 20 BWH DOS

Kimberly Khouri, MD Silviu Diaconu, MD, PGY 6 Marie Valovska, MD New York University School of Medicine Northwestern University Feinberg School of Geisel School of Medicine at Dartmouth Medicine PGY 2 PGY 2 SENIOR RESIDENTS Olivia Abbate, MD Tracy Han, MD Georgetown University School of Medicine Mario Aycart, MD, PGY 7 Duke University School of Medicine Tufts University School of Medicine Sarah Karinja, MD Kevin Melnick, MD Columbia University Vagelos College of Ravi Sood, MD, PGY 7 Emory University School of Medicine Physicians and Surgeons University of Chicago Pritzker School of Medicine Venkat Ramakrishnan, MD Eric Wenzinger, MD University of Louisville School of Medicine Medical University of South Carolina CHIEF RESIDENTS PGY 3 PGY 3 KC Collins, MD, MBA, PGY 8 Tufts University School of Medicine Erica Ditkoff, MD Jason Clain, MD Columbia University Vagelos College of Tufts University School of Medicine Ashleigh Francis, MD, PGY 8 Physicians and Surgeons McGovern Medical School at University of Brittany Vieira, MD Texas Health Science Center-Houston Gricelda Gomez, MD Northwestern University Feinberg School of Harvard Medical School Medicine Mark Greyson, MD, PGY 8 University of Virginia School of Medicine Stephen Reese, MD Frankie Wong, MD Boston University School of Medicine David Geffen School of Medicine at UCLA 2019 GRADUATES PGY 4 PGY 4 Avery Capone, MD Private Practice, Pittsburgh, PA Alexandra J. Berger, MD Timothy Irwin, MD Warren Alpert Medical School at Brown Penn State College of Medicine Ryan Cauley, MD University Reconstructive Microsurgery Fellowship, Beth Dylan Perry, MD Israel Deaconess Medical Center Manuel Ozambela, MD University of Massachusetts Medical School Harvard Medical School Shawn Diamond, MD Arman Serebrakian, MD, MS Microsurgery Fellowship, UCI School of Julie Szymaniak, MD Lewis Katz School of Medicine at Temple Medicine Rutgers Robert Wood Johnson Medical University School Brian Freniere, MD SENIOR RESIDENTS Hand Surgery Fellowship, Massachusetts PGY 5 General Hospital Lisa Gfrerer, MD, PhD, PGY 5 Hyo Sang Chiang, MD Medical University of Vienna, Austria Johanna Riesel, MD Harvard Medical School Pediatric Surgery Fellowship, Toronto Brent Pickrell, MD, PGY 5 Hospital for Sick Children, University of Jeffrey Howard, MD Baylor College of Medicine Toronto Baylor College of Medicine Jacob Rinkinen, MD, PGY 5 Danny Roh, MD, PhD Valary Raup, MD University of Michigan Medical School Plastic Surgery Faculty, Boston Medical Washington University School of Medicine in Center St. Louis CHIEF RESIDENTS Urology 2019 GRADUATES Joani Christensen, MD, PGY 6 Johns Hopkins University School of Medicine Program Director: Tyler McClintock, MD George Haleblian, MD MBA Program, Harvard Business School David Mattos, MD, MBA, PGY 6 Harvard Medical School PGY 1 Jacqueline Speed, MD Reconstructive Surgery Fellowship, Stanford Erin Taylor, MD, PGY 6 Brittany Berk, MD University School of Medicine Columbia University Vagelos College of University of Massachusetts Medical School Physicians and Surgeons Catherine Gu, MD INDEPENDENT PROGRAM Perelman School of Medicine at the University of Pennsylvania JUNIOR RESIDENTS Jason Gardenier, MD, PGY 6 University of Virginia School of Medicine BWH DOS 21

CURRENT FELLOWS Stephanie Wong, MD Cardiothoracic McGill University Medical School, Canada Surgery Transplant Acute Care Fellowship Surgery Fellowship Cardiothoracic Surgery Fellowship Program Director: Program Director: Antonio Coppolino, III, MD, MSc Reza Askari, MD Program Director: Mohamed Keshk, MD Mehreen Kisat, MD Michael T. Jaklitsch, MD Cairo University, Kasr El-Aini School Aga Khan University Medical College, of Medicine, Egypt Pakistan PGY 6 2019 GRADUATE 2019 GRADUATE Marko Boskovski, MD Yale School of Medicine Anthony Coppolino, MD Sean Hickey, MD Attending Surgeon, Brigham and Women’s Surgery Faculty, North Shore Medical Center, Anthony Cipriano, MD Hospital, Boston, MA Massachusetts General Hospital Lewis Katz School of Medicine at Temple University Colorectal Surgery Adult Cardiac Fellowship Surgery Fellowship Mia DeBarros, MD Boston University School of Medicine Program Director: Program Director: Nelya Melnitchouk, MD, MSc Tsuyoshi Kaneko, MD Julius Ejiofor, MD Peter Najjar, MD Yuji Kawano, MD UT Southwestern Medical School University of Chicago Pritzker School of Osaka University Graduate School of Medicine Medicine, Japan Desiree Steimer, MD University of Kentucky College of Medicine 2019 GRADUATE Advanced Laparoscopic Fellowship PGY 7/8 Anne Fabrizio, MD Assistant Professor of Surgery, Beth Israel Program Director: Kareem Bedeir, MD Deaconess Medical Center Ali Tavakkoli, MD Alexandria University School of Medicine, Colston Edgerton, MD Egypt Endocrine Surgery Wake Forest University School of Medicine Fellowship Hassan Khalil, MD 2019 GRADUATE McGovern Medical School at University of Program Director: Texas Health Science Center-Houston Matthew A. Nehs, MD Peter Szasz, MD Sean Wrenn, MD University of Toronto Medical School, Andrew Papoy, MD Rush Medical College Canada University of Kentucky College of Medicine 2019 GRADUATE Breast Surgery Fellowship Sunu Philip, MD University of Cape Town Medical School, T.K. Pandian, MD Program Director: South Africa Assistant Professor of Surgery, Washington Mehra Golshan, MD University School of Medicine in St. Louis Olga Cantor, MD 2019 GRADUATES University of Illinois College of Medicine Allison Laws, MD Isidore Dinga Madou, MD McMaster University School of Medicine, Cardiac Surgery Fellowship, Duke University Ontario, Canada School of Medicine 2019 GRADUATES Alexi Matousek, MD Caroline Jones McGuin, MD Attending Surgeon, Sacred Heart Medical University of Texas Southwestern Medical Center, Spokane, WA School Taufiek Konrad Rajab, MBBS 22 BWH DOS Pediatric Cardiac Surgery Fellowship, University of Colorado School of Medicine, Children's Hospital Colorado Paul Toste, MD Cardiothoracic Surgery, David Geffen School of Medicine at UCLA